Even if the destruction somehow stopped today, it will take years to rebuild.
09.03.2026 12:14
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Even if the destruction somehow stopped today, it will take years to rebuild.
Watching the systematic dismantling of the world's largest funder of biomedical research is heartbreaking and infuriating
Obligatory pic of said pet #2
Obligatory pic of said pet #1
Pet #2
Pet #1
Excited to share our work to resolve TSC2 variants of uncertain significance. Will write a proper tweetorial soon! Huge thanks to our many collaborators. This study benefited from the hard work of many folks and I appreciate them lending their time and expertise.
Excited to share our work to resolve TSC2 variants of uncertain significance. Will write a proper tweetorial soon! Huge thanks to our many collaborators. This study benefited from the hard work of many folks and I appreciate them lending their time and expertise.
Jarring homemade preserves just to seal something
I have something special to share. We premiered this incredible video last night at the dinner auction. This is a Game Tech. This is a job Child's Play created and YOUR donations make possible! Please take a few minutes to watch this and share it if you can.
vimeo.com/1140232457/1...
Omg are these going out to all dropbox hosts?? 👀
Yay always enjoy your annual jamvent posts! I am curious, about how many batches of scones does it take to get through one jamvent calendar?
congrats!!
this is Zig, my special guy. he was really talkative and loved going for walks around the neighborhood.
@coachnelly.bsky.social caught Oki Oki FC vod today. Awesome to see your progress, keep it up!
You are in for a treat! Pretty sure both were part of episodes of Make Some Noise, possibly Game Changer
Jacob and Vic are gems. That whole crew is talented but imo nothing tops Mr Mayonnaise or Evelyn Tucci
📣New today!
📄Landscapes of missense variant impact for human superoxide dismutase 1
🧑🤝🧑 @axakova.bsky.social @fritzroth.bsky.social & co
Just a reminder to check for your name in this list of books that OpenAI trained from. If your name is there, they probably owe you several thousand dollars.
OpenAI cried that if everyone eligible author files, the company will go bankrupt, so I'm alerting every author I have ever spoken to.
World Map of PAX West A) Summit - Entrance at 9th & Pine B) Arch - Entrance at 7th & Pike C) Arch (FKA Annex) - Entrance at 8th & Pike
How To: Queue for entry into the Arch Expo Hall. Doors open at 10:00 am each day.
How to: Queue for entry into the Summit Building. Doors open at 10:00 am each day.
#PAXWest 2025 is a gaming paradise spread across three buildings! Here’s a quick look at how to get around and enter each building.
For more maps & entry details visit PAXwest25.com/Maps
A well earned rest!!
I don't work with fruit flies but even I know how important FlyBase is. Such sad news. 😞
This looks super interesting, thanks for sharing!
EpiPred: A gene-specific machine learning model for classifying missense variants in the epilepsy-related gene STXBP1 https://www.biorxiv.org/content/10.1101/2025.08.09.669488v1
These are so rad!! Love your work 🤩
Happy birthday Gonzo!
This looks super interesting, can't wait to read it!
🚨 Most variant screens measure growth or abundance. What do they miss? That variants impact a spectrum of protein and cellular phenotypes. Variant in situ sequencing (VIS-seq) finds what’s missing: image cells 🔬 first, decode later, revealing multi-scale phenotypes for thousands of variants.👇
1/9
Looks like a very useful resource, thanks for putting it together. Shared it in our lab slack!
I couldn't sleep last night and skimmed through the names on the #BethesdaDeclaration support letter page.
First, the good news.
(1) There were 18,000+ names and it took me 3 hours.
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