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Prof. Sam Kariuki, BVM, MSc, PhD, DSc (Hons, LSTM)

@eadirectordndi

DNDi Eastern Africa Director. Passionate about research in tropical medicine, especially infectious diseases, neglected diseases and antimicrobial resistance.

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Latest posts by Prof. Sam Kariuki, BVM, MSc, PhD, DSc (Hons, LSTM) @eadirectordndi

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Research Roundup: Sleeping sickness drug endorsement, Potential superbug treatment, New drug-resistant bacteria approach In this regular feature on Breakthroughs, we highlight some of the most interesting reads in global health research from the past week.

What's new in #GlobalHealth R&D?
πŸ’ŠSleeping sickness drug endorsement
🦠New drug-resistant bacteria approach
πŸ”¬Potential superbug treatment

www.ghtcoalition.org/blog/researc...

09.03.2026 14:05 πŸ‘ 1 πŸ” 1 πŸ’¬ 0 πŸ“Œ 0
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The 1st single‑dose treatment for sleeping sickness has received a positive opinion from @ema.europa.eu . We are proud to have contributed to its development with @dndi.org &
@sanofi - a pill that could transform care & bring us closer to disease elimination. Read more ➑️https://bit.ly/dndi-acozi

27.02.2026 11:43 πŸ‘ 1 πŸ” 1 πŸ’¬ 0 πŸ“Œ 0
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The future of African public health must be collaborative, data-driven & above all, people-centred.

The recent partnership between @dndi.org & @aphrc.bsky.social will be a gamechanger in strengthening the health ecosystem at large. #HealthEquity
Read moreπŸ”— bit.ly/4tynePW

10.02.2026 17:43 πŸ‘ 1 πŸ” 1 πŸ’¬ 0 πŸ“Œ 0

Climate change is moving the goalposts for health.
As sandflies & mosquitoes migrate to new regions, our partnerships must move faster.

From the lab to the "last mile," we are uniting data + R&D to beat #NTDs in a warming world.

Today we #UniteActEliminate to #beatNTDs

30.01.2026 08:16 πŸ‘ 2 πŸ” 0 πŸ’¬ 0 πŸ“Œ 0
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Are you at #CPHIA2025? Join us!

Innovation is the driving force behind eliminating neglected tropical diseases #NTDs, from faster diagnostics to safer treatments & smarter surveillance tools. @dndi.org

πŸ—“οΈ24 Oct, 2025
⏲️16:00 -17:30 SAST
πŸ“Meeting Room 12CD, Durban ICC

24.10.2025 10:06 πŸ‘ 1 πŸ” 0 πŸ’¬ 0 πŸ“Œ 0
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The annual programme review meeting for visceral ##leishmaniasis in Eastern Africa has started in Kampala, Uganda with @dndi.org and The END Fund.

Looking forward to fruitful deliberations on addressing challenges and closing the gaps through partnerships to achieve elimination. #ZeroLeish

30.09.2025 10:16 πŸ‘ 5 πŸ” 3 πŸ’¬ 0 πŸ“Œ 0
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We’re excited for @dndi.org to be receiving the Hideyo Noguchi Africa Prize in Japan at #TICAD9 in the medical services category for our work in transforming lives and driving innovation where it’s needed most. #GlobalHealth #EndTheNeglect

22.08.2025 12:03 πŸ‘ 2 πŸ” 1 πŸ’¬ 0 πŸ“Œ 0
3 Dangerous Mosquitoes
3 Dangerous Mosquitoes YouTube video by Drugs for Neglected Diseases initiative (DNDi)

🦟3 mosquito species transmit some of the most devastating diseases: aedes, anopheles, culex.

Together with partners like @mmv.org, we're working to develop safe, affordable & effective treatments against mosquito-borne diseases.

#WorldMosquitoDay

www.youtube.com/shorts/NOLiF...

20.08.2025 10:09 πŸ‘ 12 πŸ” 2 πŸ’¬ 0 πŸ“Œ 0
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πŸŽ‰Congratulations to Kenya for eliminating rhodesiense #SleepingSickness as a public health problem.
πŸ‘A huge win for public health & innovation. We are happy that our work has supported safer, simpler treatments for this disease in Africa. bit.ly/4oiAMw6 #SleepingSicknessFreeKenya

08.08.2025 09:31 πŸ‘ 3 πŸ” 1 πŸ’¬ 0 πŸ“Œ 0
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We are proud of Kenya's achievement in eliminating #sleepingsickness as a public health problem, becoming the 10th Nation to eliminate the disease globally.

Elimination is not eradication. We look forward to full integration of HAT interventions in healthcare systems. #beatNTDs bit.ly/45NE6XV

08.08.2025 10:02 πŸ‘ 0 πŸ” 0 πŸ’¬ 0 πŸ“Œ 0
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Patients like Jennifer silently suffer from #mycetoma, a disease whose global burden is unknown.

@dndi.org and partners are working to reduce disease knowledge gaps & bolster international partnerships to establish transnational clinical studies bit.ly/45jOfet #beatNTDs

01.08.2025 13:04 πŸ‘ 1 πŸ” 0 πŸ’¬ 0 πŸ“Œ 0
Celebrating six African women at the forefront of global health R&D To celebrate the achievements of African women, we’re spotlighting six African women researchers who have made significant contributions to global health research and supported the next generation of ...

Celebrating my colleague Dr Monique Wasunna, one of six inspiring African women spotlighted by @ghtcoalition.org.

Her leadership in driving transformative trials in #leishmaniasis & #sleepingsickness have contributed to accelerated access to affordable, life-saving treatments. bit.ly/4lIi2Ez

30.07.2025 13:29 πŸ‘ 3 πŸ” 0 πŸ’¬ 0 πŸ“Œ 0
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Antimicrobial Resistance: a global crisis we can't ignore Microbes may be smallβ€”but when they become resistant to antibiotics, they cause BIG problems. For over 100 years, antibiotics have protected us: curing infections, enabling life-saving surgeries, and shielding the most vulnerable. But that protection is under threat. Drug-resistant infections are now one of the world’s biggest killersβ€”linked to nearly 5 million deaths each year. Without urgent action, the crisis will escalate, putting lives everywhere at risk. Our campaign video highlights the urgent need to actβ€”before it’s too late. Learn more: https://gardp.org/this-is-big/ πŸ›‘ Drug resistance is not a future threat. It’s happening now. #StopSuperbugs #AMR #AntibioticResistance #GARDP #Superbugs #DrugResistance #PublicHealth

Antimicrobial resistance is on track to cause 70% more deaths by 2050.The solution? Not just new antibiotics, but fair access to them.

GARDP is reimagining antibiotic R&D by centering people’s health, not just profits. #ThisIsBig #GlobalHealth bit.ly/4lVCguH

25.07.2025 13:19 πŸ‘ 1 πŸ” 1 πŸ’¬ 0 πŸ“Œ 0
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Five patients have been successfully treated for #sleepingsickness using a new all-oral drug, Fexinidazole Winthrop after successful clinical trials by @dndi.org

This marks a milestone in the fight against human African trypanosomiasis #NTD spread by tsetse flies. More ➑️ bit.ly/4f7xZln #beatNTDs

25.07.2025 10:30 πŸ‘ 4 πŸ” 2 πŸ’¬ 0 πŸ“Œ 0
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About 50% of people with #leishmaniasis are children. Our goal at @dndi.org is to continue implementing safer, shorter treatments with existing drugs while advancing the development of all-new treatments for affected communities.

Read more in the annual reportπŸ‘‰https://bit.ly/4eT4l3c #EndTheNeglect

22.07.2025 12:55 πŸ‘ 5 πŸ” 3 πŸ’¬ 0 πŸ“Œ 0
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Despite the ongoing conflict in Sudan, @dndi.org is actively working on the registration of fosravuconazole treatment, following favourable response on sharing the clinical results with the Sudan Regulatory Authority. @whoemro.bsky.social
#EndTheNeglect #beatNTDs #HealthForAll

16.07.2025 13:02 πŸ‘ 1 πŸ” 1 πŸ’¬ 0 πŸ“Œ 0
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"We are working to bridge the knowledge gap on #mycetoma through epidemiological studies in Kenya, Senegal, Ethiopia and India. Lack of investment, research, access to diagnosis and treatment is contributing to the neglect," said
@bornanyaoke.bsky.social

16.07.2025 13:02 πŸ‘ 1 πŸ” 1 πŸ’¬ 1 πŸ“Œ 0
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"There is urgent need for shorter more effective treatments, proper diagnostics tests & point of care tests," said Prof. Ahmed Fahal.

For the last 33 years, the Mycetoma Research Centre
together with partners has been providing #mycetoma management, research & community engagement for patients.

16.07.2025 12:57 πŸ‘ 0 πŸ” 0 πŸ’¬ 0 πŸ“Œ 0
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"In many #mycetoma endemic countries, information on the disease burden is scanty, making it hard to achieve #UHC," said DrDaniel Ngamije.

@who.int remains committed to supporting countries & partners in integrating skin NTD interventions within primary health care systems. #beatNTDs #HealthForAll

16.07.2025 12:48 πŸ‘ 1 πŸ” 1 πŸ’¬ 0 πŸ“Œ 0
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DNDi 2024 Annual Report Browse our interactive Annual Report to learn how solidarity in science is benefiting the most neglected.

The @dndi.org 2024 Annual Report is out!

Despite global challenges, we advanced 46 R&D projects across 7 diseases, with 4,214 patients enrolled in clinical trials.
Solidarity in science is working.

Read the report here➑️ bit.ly/4eT4l3c

16.07.2025 09:33 πŸ‘ 3 πŸ” 0 πŸ’¬ 0 πŸ“Œ 0
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Join Dr Borna Nyaoke and Prof. Ahmed Fahal tomorrow 16 July, 2025 during the webinar on #mycetoma as they discuss how to advance research especially after the destruction of the Mycetoma Research Center in Sudan. #beatNTDs #EndTheNeglect

Register ➑️ bit.ly/3GDcL1Q
⏲️2:00 - 4:00PM Cairo Time (GMT+3)

15.07.2025 15:01 πŸ‘ 0 πŸ” 0 πŸ’¬ 0 πŸ“Œ 0

The new project #IMPAACT4HIV in the DRC aims to improve care for people with advanced HIV disease (AHD).

The initiative decentralizes care to local clinics, enabling earlier diagnosis, faster treatment & stronger community support.

15.07.2025 12:41 πŸ‘ 1 πŸ” 1 πŸ’¬ 0 πŸ“Œ 0

Register for this upcoming webinar on #mycetoma with @who.int
πŸ“† Wednesday 16 July, 2025
πŸ•‘ 14:00 - 16:00PM (GMT+3)
πŸ”— Register here ➑️ bit.ly/3GDcL1Q

11.07.2025 13:21 πŸ‘ 2 πŸ” 0 πŸ’¬ 0 πŸ“Œ 0

🧠 Health = empowerment.
🌍 Equity = eliminating NTDs.
πŸ‘£ The future = youth-led, disease-free.

Let’s act now to #EndTheNeglect by investing in youth health, supporting NTD elimination and amplifying the voices of those affected. @dndi.org

11.07.2025 13:02 πŸ‘ 0 πŸ” 0 πŸ’¬ 0 πŸ“Œ 0
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On #WorldPopulationDay, we’re spotlighting a silent crisis: Neglected Tropical Diseases (NTDs).

This year’s theme, 'Empowering young people to create the families they want in a fair and hopeful world' means nothing if youth are held back by diseases that rob them of health, opportunity & choice.

11.07.2025 13:02 πŸ‘ 1 πŸ” 1 πŸ’¬ 1 πŸ“Œ 0
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πŸ“’ Press release: The antimalarial toolbox just expanded, bringing hope to the smallest patients. The first #malaria treatment for newborns and young infants has been approved by @swissmedic.bsky.social, with fast-track approvals expected across Africa.

08.07.2025 08:33 πŸ‘ 9 πŸ” 6 πŸ’¬ 1 πŸ“Œ 2

From clinical studies in Brazil & Ethiopia to our commitment to gender equity in clinical trials, we're pushing for innovation that leaves no one behind.

Let’s #EndTheNeglect and bring dignity, visibility, and solutions to those living with cutaneous leishmaniasis. #BeatNTDs

08.07.2025 14:36 πŸ‘ 0 πŸ” 0 πŸ’¬ 0 πŸ“Œ 0
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Today is #WorldSkinHealthDay, we spotlight cutaneous #leishmaniasis (CL), a skin disease caused by parasites transmitted by sandflies.

At @dndi.org we’re working with partners to develop new, safer & more effective treatments.

08.07.2025 14:36 πŸ‘ 3 πŸ” 1 πŸ’¬ 1 πŸ“Œ 0

Read the @gardp.bsky.social annual report to know more about their progress in supporting equitable and appropriate access to antibiotics. #ThisIsBig πŸ”— bit.ly/3TqYyYG

04.07.2025 09:22 πŸ‘ 1 πŸ” 0 πŸ’¬ 0 πŸ“Œ 0
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Clinical lactation studies. Acting on key recommendations over the last decade Including lactating women in clinical trials is imperative to generate relevant drug exposure and safety data needed to advise on clinical use of drugs in this understudied population. Recent changes ...

If we want equitable, safe, and effective treatments for all, we must stop treating breastfeeding women as an afterthought in drug development.
Inclusion isn’t optional, it’s essential. Read more from this study bit.ly/4nw2XaC

02.07.2025 13:26 πŸ‘ 1 πŸ” 0 πŸ’¬ 0 πŸ“Œ 0