1/7 🧠 My journey into development begins with this work and question: how does the brain's spatial navigation system develop? We found that the neural networks for spatial navigation (tori and rings) are preconfigured and only later anchor gradually to the world with experience! 🧵
Happy belated publication of some of my PhD work!
Building on our findings that grid field firing rate changes can cause hippocampal remapping and memory impairment, here we show that this effect has a fixed input-output relationship, and we can even predict how place cells will remap!
One ring to rule them all….
We had a lot of fun doing these experiments! Theta sweeps in MEC and internal direction signals in parasubiculum track moving objects during pursuit and reverse during backward movement. Simultaneously recorded HD cells in other areas remain locked to head direction across behaviors:
The research group “Sensory Dynamics and Behaviour” of Prof. Dr. Tobias Ackels at the Institute of Experimental Epilepsy and Cognition Research at the University Hospital Bonn invites applications for a position as: Postdoctoral Researcher (m/f/d) The position is initially limited to three years (TV-L E13/100%), starting from April 2026 or as soon as possible.
Postdoc position in systems neuroscience!
Excited to recruit a postdoc for my lab at the University of Bonn.
🔬 In vivo physiology (Neuropixels, 2P/miniscope)
🐭 Head-fixed & freely moving behaviour
💡 Optogenetics/chemogenetics
⏳ Start: ASAP | Application deadline: 28.02.2026
More info below ⬇️
this is 🔥🔥! congrats to you and the team!!
⚠️ New paper alert and what a way to end 2025! 🎉
Happy to share our story “Sleep-dependent infraslow rhythms are evolutionarily conserved across reptiles and mammals.” published today in Nature Neuroscience.
Sleeping dragons 🦎 and functional ultrasound!
Read the full paper here: rdcu.be/eWJHb 1/8
Looking for a postdoc to understand dynamic vision in action in freely moving mice? Get in touch!
This is a @erc.europa.eu postdoc in a project between us and @sinzlab.bsky.social: miniature 2-photon, rich behavior tracking, and deep learning models linking natural behavior to cortical activity|RT
The Sosa Lab is going to #SfN25 and actively recruiting ✨postdocs✨ with systems neuroscience experience! We study both fundamental memory processes and how memory changes during pregnancy and postpartum.
If you are interested in meeting at SfN, please email me! www.sosaneurolab.com/join/postdoc...
Come do a postdoc at the Wu Tsai Institute!
WTI fellows have freedom to work with anyone at the institute, and preference is given to applicants who want to work on interdisciplinary projects with multiple faculty mentors.
If you’re interested to work with me, please reach out!
congrats Adrian!! 🤩
Really excited to share this Opinion piece we've been working on with fellow head-direction cell geeks @apeyrache.bsky.social @desdemonafricker.bsky.social and (bsky-less?) Andrea Burgalossi! While head-direction cells pop up in many cortical regions, we think that one of them is quite unique (1/8)
The Sosa Lab website is now live!
www.sosaneurolab.com
We will be seeking a postdoctoral researcher to join the growing team! If you are a rodent neuroscientist and interested in doing systems neuro work in the mountains 🏔️, please check out the "Join" page.
congrats to the team🎉🥂
Stoked to see this paper finally out!
It answers two big questions: where visual objects are encoded in the brain, and how head-direction cells get oriented using visual landmarks.
Super fun collaboration with @mace-lab.bsky.social and Stuart Trenholm.
www.science.org/doi/10.1126/...
📣 We are expanding! Repost 🙏🏽
- Postdoc (funded by @simonsfoundation.org grant on synchronisation between cognitive representations and stepping)
- Project Associates
- Create your role! (Reach out if you are keen on these topics and these roles do not define you 👀🤗)
www.neuroact.in
congrats!!🎉
Thrilled to announce I'll be starting my own neuro-theory lab, as an Assistant Professor at @yaleneuro.bsky.social @wutsaiyale.bsky.social this Fall!
My group will study offline learning in the sleeping brain: how neural activity self-organizes during sleep and the computations it performs. 🧵
Our new paper out now in Science explores how neural activity in the lateral entorhinal cortex (LEC) *drifts* over time - and *jumps* at key boundaries - to help organize events in memory.
🔗 www.science.org/doi/10.1126/...
Here's a quick summary of what we found 🧵👇
Brightly labelled pyramidal cells in the mouse retrosplenial cortex. Blood vessels are visible of various thicknesses in darker colours.
#neuroskyence folks: as my postdoc grant is running out soon, I am looking for new opportunities in systems neuroscience!
Keywords: patch clamp ephys, opto, mouse behavior, (in vivo) voltage imaging. Would love to return to the Basal Ganglia.
Sharing appreciated, and happy #FluorescenceFriday !
That's truly exciting news! Congrats Mari!!
Congrats @markcembrowski.bsky.social 🤩! certainly well deserved!!!!
I joined this podcast to talk about sleep, dreams, and James Joyce. Yes, all in one conversation. It was a lot of fun!
🔊 Heads up: the audio is a bit rough at the start, but it clears up quickly.
Listen here: podcasts.apple.com/ca/podcast/b...
thanks Horst!
thanks, Quinn!
Lastly, a big shoutout to @mcgill.ca @theneuro.bsky.social IPNMcGiLL , and a heartfelt thanks to the grant gods 💸:Vision Health Research Network (VHRN), @hbhlmcgill.bsky.social @CIHR_IRSC @NSERC_CRSNG @sloanfoundation.bsky.social for funding this work!
Cheers!
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Huge thanks to the authors behind all the foundational studies that inspired this work, to my amazing advisors (@apeyrache.bsky.social and Stuart Trenholm), and to the brilliant members of the Peyrache and Trenholm labs for their support.
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In summary, we provide a direct link between stereo olfaction and the HD system in blind mice, and highlight the contribution of HD cells to allocentric spatial navigation.
7/
We also tested blind mice with bilateral ablation of olfactory sensory neurons on the task.
And as expected, their performance tanked!
6/
Interestingly, during rewarded trials, mice with one nostril blocked adopted a "hunting" strategy: scanning until they randomly hit the target, then used self-motion cues to secure extra rewards. However, once they strayed too far, they were unable to relocate the target.
