Marian Walhout's Avatar

Marian Walhout

@marianwalhout

Biologist, systems biology, C. elegans, metabolism, gene regulation, networks, horses, cats, (still) happy in academia, UMass Chan Medical School https://www.umassmed.edu/walhoutlab/ Opinions my own

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01.12.2024
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Latest posts by Marian Walhout @marianwalhout

Feeling inspired by the @scifri.bsky.social story about cat genetics and behavior? Well, you can do science too! Investigate how your favorite pet communicates with you in this fun, family-friendly STEM activity. #EduSky www.sciencefriday.com/educational-...

21.04.2025 17:45 πŸ‘ 49 πŸ” 8 πŸ’¬ 0 πŸ“Œ 0
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If we fit, we sit.. πŸ˜‚

19.04.2025 06:02 πŸ‘ 1341 πŸ” 157 πŸ’¬ 12 πŸ“Œ 17

Senior and junior faculty in the current NIH-quake

16.04.2025 14:57 πŸ‘ 2 πŸ” 0 πŸ’¬ 0 πŸ“Œ 0

I will be like these cows when my foot surgery is done and healed!

16.04.2025 14:53 πŸ‘ 0 πŸ” 0 πŸ’¬ 0 πŸ“Œ 0
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In Sweden, crowds line up just to watch cows go outside for the first time since winter.. 😊

15.04.2025 19:26 πŸ‘ 1413 πŸ” 159 πŸ’¬ 37 πŸ“Œ 32
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Comforting each other.. 😊

05.04.2025 11:24 πŸ‘ 1541 πŸ” 160 πŸ’¬ 16 πŸ“Œ 14
Hoopoe feeding

Hoopoe feeding

Hoopoe with a worm.

Hoopoe with a worm.

Hoopoe with a worm.

Hoopoe with a worm.

Hoopoe swallowing a worm.

Hoopoe swallowing a worm.

Hoopoe, East Cork - part of a recent influx of these exotic beauties to southern Ireland. #birds #BirdsSeenIn2025

02.04.2025 06:56 πŸ‘ 115 πŸ” 12 πŸ’¬ 5 πŸ“Œ 0
Eight Sandhill Cranes take flight at first light after roosting overnight on the Platte River in Nebraska. A nearly full moon backs the birds, as the sky just begins to take on a pink hue.

Eight Sandhill Cranes take flight at first light after roosting overnight on the Platte River in Nebraska. A nearly full moon backs the birds, as the sky just begins to take on a pink hue.

I am buzzing with excitement just back from another trip to see this spectacle! There is something profound about the great Sandhill Crane migration at the Platte River. Each morning is like tuning in live to nature’s crescendoβ€”soft purrs in low light transform into a booming, prehistoric orchestra.

31.03.2025 20:45 πŸ‘ 180 πŸ” 22 πŸ’¬ 9 πŸ“Œ 1
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31.03.2025 17:15 πŸ‘ 266 πŸ” 30 πŸ’¬ 7 πŸ“Œ 3
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A rare seven-planet β€˜parade’ will light up the sky. Here’s how to see it. The planetary alignment will be visible Friday night, but not all of them can be seen by the naked eye.

If you bring a telescope and get away from city lights Friday evening, there’s a chance you’ll see seven planets parading through the sky.

27.02.2025 17:18 πŸ‘ 274 πŸ” 62 πŸ’¬ 19 πŸ“Œ 11

Thanks Juan - it's so nice seeing all the work we've done over the years come to this. Fei and Hang are amazing scientists. See you in a week or two!

26.02.2025 17:35 πŸ‘ 0 πŸ” 0 πŸ’¬ 0 πŸ“Œ 0
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Systems-level design principles of metabolic rewiring in an animal - Nature Systems-level Worm Perturb-Seq of metabolic genes reveals design principles of transcriptional metabolic rewiring, many of which can be explained by a compensation–repression model.

Here's the second one! PD applications welcome
www.nature.com/articles/s41...

26.02.2025 17:03 πŸ‘ 7 πŸ” 3 πŸ’¬ 2 πŸ“Œ 0
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A systems-level, semi-quantitative landscape of metabolic flux in C. elegans - Nature A strategy is introduced that infers whole-animal metabolic flux wiring from transcriptional phenotypes in the nematode Caenorhabditis elegans and several features in its adult metabolism are discover...

Two papers out in Nature today! Super exciting work by an amazingly talented team - Hefei Zhang and Xuhang Li. Proud and thrilled to see these out.
www.nature.com/articles/s41...

26.02.2025 17:02 πŸ‘ 14 πŸ” 3 πŸ’¬ 2 πŸ“Œ 1
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Two papers by Walhout lab in Nature highlight novel metabolic principles Two papers published today in the journal Nature describe a significant advance in understanding the complex functions of the metabolic network.

Two papers published today in Nature describe a significant advance in understanding the complex functions of the metabolic network. Read about new research from the lab ofβ€―Marian Walhout, PhD: direc.to/mNpf

#metabolic #metabolism @marianwalhout.bsky.social
@nature.com @natureportfolio.nature.com

26.02.2025 16:57 πŸ‘ 8 πŸ” 6 πŸ’¬ 1 πŸ“Œ 1
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Should biology put complexity first? The dictum β€œEverything should be made as simple as possible, but no simpler” poses a problem for biology. How simply can it be told without doing damage to its complex nature? The answer might be foun...

A must read for any (systems) biologist!
www.cell.com/cell-systems...

20.02.2025 13:42 πŸ‘ 6 πŸ” 5 πŸ’¬ 0 πŸ“Œ 0
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❀️

18.02.2025 18:24 πŸ‘ 1274 πŸ” 107 πŸ’¬ 13 πŸ“Œ 7
Enhanced flux potential analysis links changes in enzyme expression to metabolic flux

www.embopress.org/doi/epdf/10.....
Please check out Xuhang's exciting article in MSB!

18.02.2025 11:40 πŸ‘ 8 πŸ” 6 πŸ’¬ 0 πŸ“Œ 0

Trying to keep calm by watching the most beautiful thing ever - on repeat...
www.youtube.com/watch?v=0vEP...

10.02.2025 00:20 πŸ‘ 3 πŸ” 0 πŸ’¬ 0 πŸ“Œ 0
Quantifying metabolites using structure-switching aptamers coupled to DNA sequencing Nature Biotechnology - Metabolites can be quantified using a combination of aptamers and DNA barcodes.

Super cool paper from Andy Fraser @andyfraser.bsky.social
rdcu.be/d8AVv

04.02.2025 17:58 πŸ‘ 6 πŸ” 3 πŸ’¬ 1 πŸ“Œ 0
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Worm Perturb-Seq: massively parallel whole-animal RNAi and RNA-seq The transcriptome provides a highly informative molecular phenotype to connect genotype to phenotype and is most frequently measured by RNA-sequencing (RNA-seq). Therefore, an ultimate goal is to pert...

Check out our new paper in BioRxiv: www.biorxiv.org/content/10.1...
Amazing work by Fei and Hang! More to come.

04.02.2025 14:51 πŸ‘ 9 πŸ” 1 πŸ’¬ 0 πŸ“Œ 0
#Π²ΠΎΡ€ΠΎΠ½Π³ΠΎΡˆΠ° #raven #ravengosha #animal #ravenbird #birds #nature
#Π²ΠΎΡ€ΠΎΠ½Π³ΠΎΡˆΠ° #raven #ravengosha #animal #ravenbird #birds #nature YouTube video by Π’ΠΎΡ€ΠΎΠ½ TV

Mandatory curriculum for any graduate student or post-doc πŸ˜†
www.youtube.com/shorts/vavfB...

09.01.2025 23:30 πŸ‘ 0 πŸ” 0 πŸ’¬ 0 πŸ“Œ 0
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Wait for it.. 😊

04.12.2024 22:33 πŸ‘ 2103 πŸ” 201 πŸ’¬ 34 πŸ“Œ 17