Added to my reading list!!! ππΌ thanks for sharing π
Added to my reading list!!! ππΌ thanks for sharing π
A four-panel figure showing scanning electron micrographs of Pseudomonas biofilm on the surface of pig lung tissue. Aggregates of bacteria sit on top of a network of collagen fibrils, with some bacterial cells penetrating the collagen mesh.
Paper out! We used RNAseq to track changes in P. aeruginosa gene expression over 7 days of #biofilm infection in our #CysticFibrosis lung model. www.microbiologyresearch.org/content/jour... #MicroSky (1/n)
Recurrent and chronic UTIs have a huge impact on patient's quality of life and is an area of research which is often overlooked and understudied. There are massive gaps in our understanding which we can fill to... (1/3)
See all images in this post and that follow for the top 10!
#MicroSky #UTISky
You can read the full preprint here: www.biorxiv.org/content/10.6...
Work by Jenny Littler, Niamh Harrington, Dean Walsh, @microberamon.bsky.social, Chris Parmenter @uonnmrc.bsky.social & Saskia Bakker #MicroSky
Four graphs, showing the response of PA14 and an isogenic pel mutant, and PAO1 and an isogenic pel psl double mutant, to meropenem and colistin. There is no difference between the response of mutants and WTs.
During her PhD, Jenny found something unexpected: biofilm-deficient P. aeruginosa mutants were just as tolerant to antibiotics as the WT when grown in our cystic fibrosis lung model. But why? #MicroSky 1/n
Congratulations!!!! π₯³ amazing news!!!
Now, this is officially a problem. MSCA fellowships need to be competitive, but it cannot be a lottery. Time to focus on the core mission of supporting science and ditching all vanity initiatives in the Horizon Europe program. (Looking at ERC super-grants...)
Excited to share our preprint that describes the mechanism of action of an historical infection remedy called Baldβs Eyesalve. In this preprint, we show that Baldβs Eyesalve has multifaceted mechanism of action against both S. aureus and A. baumannii (1/n).
Less than one week to apply to this 2.5 yr PDRA!
If you're passionate about biophysics #AFM #Microscopy applied to bacteria and #antimicrobial research this will be a great opportunity in the beautiful city of Sheffield. π
jobsite.sheffield.ac.uk/job/Research...
Confocal micrograph of a purple urothelium covered with bacteria - see https://www.biorxiv.org/content/10.1101/2025.11.12.688052v1
Pleased to reveal that our team has been selected for 2 oral presentations at #ESCMID
@escmid.bsky.social Global in Munich! Both lines of research spearheaded by the fabulous @microberamon.bsky.social. #UTI isnβt just a serious healthcare problem - the science is an intriguing puzzle! #IDSky #UTISky
Gut-relevant short-chain fatty acids modulate host-pathogen dynamics of uropathogenic Escherichia coli at the colonic epithelial interface https://www.biorxiv.org/content/10.64898/2026.01.19.700340v1
π§΅Enterococcus faecalis is not just an extracellular organism. π§΅ A growing body of work shows it can survive + REPLICATE inside host cells, and that intracellular life may seed persistence, dissemination, and reinfection. 1/n #MMBR @asm.org journals.asm.org/doi/10.1128/...
Congratulations!!!!!! π₯³π₯³ in my reading list!!! ππΌ
Happy birthday Jenny!!! π₯³
Congratulations @tosinorababa.bsky.social π₯³π₯³π₯³
Very pleased to plug our latest preprint, lead author @microberamon.bsky.social - fantastic collaboration with labs of Dario Carugo (Oxford) and Martha Clokie (Leicester) https:// - and others #UTISKy #UTI #IDSky #MicroSky www.biorxiv.org/content/10.1101/2025.11.12.688052v1 more belowππ§΅
PhD opportunity in my lab: exploring how commensals and pathogens build biofilm communities on endotracheal (ventilator) tubes. Microbial ecology, medical microbiology and fancy imaging! Co-supervised with the fabulous Saskia Bakker and Jeremy Webb warwick.ac.uk/fac/cross_fa... #MicroSky
A cartoon showing a Gram-negative bacterium exposed to two variants of a polymer. A triblock structure causes formation of multiple small pores in the outer membrane. A diblock structure causes large pores in both outer and inner membranes, and cell lysis.
Another paper from @microberamon.bsky.social's PhD π¦ Two structural variants of an AMP-inspired antimicrobial polymer have different effects on P. aeruginosa. One kills with a bang, the other with a whimper pubs.acs.org/doi/10.1021/... #MicroSky @sebperrier.bsky.social @alexiahapeshi.bsky.social
Massive thanks to all the authors, what a ride! Couldnβt have done it without you π @laia-pasquina.bsky.social @friendlymicrobe.bsky.social @alexiahapeshi.bsky.social @sebperrier.bsky.social and the wizard of NR Steve Hall
π§Ό a-D50 acts in a surfactant-like way, stripping lipids
π³οΈ a-T100-1 forms pores in the membrane
Same chemistry, different architecture β different mechanisms.
π Super happy to finally share our new paper in ACS Biomacromolecules!
We used AFM & neutron reflectometry to study how two SNAPs (synthetic nanoengineered antimicrobial polymers) disrupt P. aeruginosa membranes.
π pubs.acs.org/doi/10.1021/...
#SNAPs #AFM #NeutronReflectometry #AMR
So in denial that I cannot open my eyes π₯Ήπ€£
π₯Ή not going far!!!! πͺ
I guess we can call this Cellfie π
Interesting cross-disciplinary technician position in our lab! You can learn all things microbiology and a beautiful organoid culture system while sitting in the heart of London @ucl.ac.uk ! Perfect for freshly graduated students. Apply! #UTISky #microbiology
Really cool exhibition at the London Design Biennale 2025. Microbiome Modulators as bioactive ceramics and probiotic interventions embedded in ceramic elements π¦
bbe.ac.uk/living-assem...
Proud to present my work at the UK Cellular Microbiology Network Meeting earlier this week. Lots of great feedback and some very interesting talks! Congrats to all the speakers. Well done @microberamon.bsky.social for representing the lab. I like the rainbow title slide π @jennyrohn.bsky.social
A man gesturing at a presentation on a stage.
Great talk about polymicrobial biofilms in #UTI by our fabulous postdoc @microberamon.bsky.social! #UKcellmicro2025 #UTISky
Really excited about this opportunity! I will be sharing part of my postdoc work at Rohn lab @jennyrohn.bsky.social and a new hairstyle πββοΈπ