The Lancet Microbe

Safety of MVA-BN vaccine in health-care personnel in DR Congo: a prospective cohort study This study adds to the growing body of literature on the safety of MVA-BN in different populations. Although limited by incomplete grading of specific adverse events, low numbers of pregnant participa...

Safety of MVA-BN vaccine in health-care personnel in DR Congo: a prospective cohort study

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Immunogenicity and safety of MVA-BN vaccine administered 5 years after a two-dose primary series in DR Congo: a prospective cohort study These data show that primary MVA-BN vaccination induces sustained immunological memory up to 5 years after vaccination and that a booster dose strongly enhances circulating antibody levels and durabil...

Immunogenicity and safety of MVA-BN vaccine administered 5 years after a two-dose primary series in DR Congo: a prospective cohort study

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A combined ELISA for infection-induced and vaccine-induced mpox antibodies during the clade Ib outbreak in Rwanda: an observational, cross-sectional, clinical validation study We show that an mpox ELISA can be implemented within a national reference laboratory in a resource-limited setting as part of outbreak-response measures. The assay is suitable for population-level sur...

A combined ELISA for infection-induced and vaccine-induced mpox antibodies during the clade Ib outbreak in Rwanda: an observational, cross-sectional, clinical validation study

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Case presentation of patients hospitalised with mpox (subclade Ib/2023sh) including children, adolescents, and adults in South Kivu, Democratic Republic of the Congo: an observational cohort study The high proportion of children and adolescents (aged ≤15 years) differentiates our cohort from other clinical descriptions of the novel MPXV subclade Ib/2023sh. Given that, we hypothesise a demograph...

Case presentation of patients hospitalised with mpox (subclade Ib/2023sh) including children, adolescents, and adults in South Kivu, Democratic Republic of the Congo: an observational cohort study

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From emergency to integration: research as the bridge in mpox control The lifting of the status of mpox as a Public Health Emergency of Continental Security (PHECS) is a major epidemiological and political milestone.1 However, this change in status should not be confuse...

A bumper crop of mpox content - 1 comment and 4 research articles 👇

From emergency to integration: research as the bridge in mpox control

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New research article

Clinical prevalence of collateral sensitivity: a systematic exploration of multicentre antimicrobial surveillance data

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#IDSky #ClinMicro #AMR #OpenAccess #OA

(Un)intended consequences: a social sciences stocktake of a decade of Global Action Plan-inspired antimicrobial governance Antimicrobial resistance (AMR) remains a major global health threat. Despite increasing international attention, AMR governance has often neglected social and equity dimensions, and there is a crucial...

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Claas Kirchhelle and Lloyd Czaplewski on AMR governance and financing - The Lancet Microbe in conversation with Elena Dalla Vecchia talks with Claas Kirchhelle and Lloyd Czaplewski about the current antimicrobial resistance (AMR) governance (with a historical perspective on how it came to be), the 2015 WHO Glob...

Great fun to chat about #antimicrobials, #innovation & #AMR - including our recent stocktake of the (un)intended consequences of the WHO's 2015 Global Action Plan with Lloyd Czaplewski & Elena Dalla Vecchia on @lancetmicrobe.bsky.social "In Conversation"!

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Cover art for The Lancet Pulse, a new podcast from The Lancet Group. A gradient blue square is overlaid by circles of increasing size, like ripples on a lake.

Introducing The Lancet Pulse—a new podcast translating science into real-world clinical insights.

Editors from The Lancet and leading global experts unpack the hot topics shaping medicine and patient care. spkl.io/63320AQeua

The role of microbial genomics in delivering the UK’s national action plan for confronting antimicrobial resistance 2024–29 Antimicrobial resistance (AMR) is a major threat to human and animal health, in addition to environmental resilience. Countries set the agenda on their national action against AMR in the form of Natio...

What is the role of #microbial #genomics in delivering the #UK National Action Plan (NAP) for confronting #AntimicrobialResistance ( #AMR ) 2024-29? Read our new open-access #OA piece in @lancetmicrobe.bsky.social exploring this topic from various expertise🛟🧪🧬🖥️🦠💉🧫😷
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The role of microbial genomics in delivering the UK’s national action plan for confronting antimicrobial resistance 2024–29 Antimicrobial resistance (AMR) is a major threat to human and animal health, in addition to environmental resilience. Countries set the agenda on thei…

Delighted by this @target-amr.bsky.social publication in @lancetmicrobe.bsky.social. Led by @drtessjohnson.bsky.social and @lewiscemason.bsky.social

'The role of microbial genomics in delivering the UK’s national action plan for confronting AMR 2024–29'

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New personal view article

The role of microbial genomics in delivering the UK’s national action plan for confronting antimicrobial resistance 2024–29

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#IDSky #ClinMicro #AMR #OpenAccess #OA

New personal view article

Research on the genome of microorganisms: ethical considerations and recommendations regarding the incidental bystander sequencing of human genetic material

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#IDSky #ClinMicro #OpenAccess #OA

New research article

CRISPR-Cas-based diagnostics for point-of-care detection of sexually transmitted infections: a laboratory development and evaluation study

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#IDSky #ClinMicro #STI #OpenAccess #OA

"although AMR is framed as a One Health threat, underpinned by system interconnectedness, interventions are often designed to induce changes to individual behaviour (eg, that of farmers or antibiotic prescribers or users), without accounting for contextual constraints"

In advance of our March issue here is our latest editorial

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#IDSky #ClinMicro #AMR #OpenAccess #OA

New research article

Invasive #aspergillosis in liver #transplant recipients in France (2007–21): a nationwide, retrospective, matched case–control study

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#IDSky #ClinMicro #MycoSky #OpenAccess #OA

New research article

Safety, recovery, and pharmacodynamics of CRISPR–Cas therapeutic SNIPR001: a phase 1, randomised, double-blind, first-in-human, dose-escalation study

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#IDSky #ClinMicro #AMR #OpenAccess #OA

New research article

Predicting bloodstream infection by plasma cell-free metagenomic sequencing: a prospective cohort study

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#IDSky #ClinMicro #OpenAccess #OA

Alt: Cover art for The Lancet Pulse, a new podcast from The Lancet Group. A blue square is overlaid by circles of increasing size, like ripples on a lake.

Introducing a new Lancet podcast 🎙️

Every month, The Lancet Pulse explores the latest advances and toughest challenges in clinical medicine.

Listen to episodes 0 through 3 today: spkl.io/63320AQeDi

Read our March issue!

Featuring RSV vaccination in elderly people, itraconazole for pulmonary aspergillosis and the global burden of Chagas disease.

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📰 Comment: Three reasons why the European region should worry about #tuberculosis

"Ongoing deaths, conflicts, and forced migration must motivate us to act and do more to end tuberculosis worldwide"

🔓 Read in full here: www.thelancet.com/journals/lan...

@madhupai.bsky.social @who.int

New research article

Characterisation of #Bordetella #pertussis virulence and macrolide resistance in Australia by targeted culture-independent sequencing: a genomic epidemiology study

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#IDSky #ClinMicro #AMR #OpenAccess #OA

New personal view article

Spillover of #pseudorabies virus variants to humans: an urgent call for pseudorabies eradication in domestic pigs

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#IDSky #ClinMicro #ViroSky #zoonosis #OpenAccess #OA

📢NEW: February issue now online featuring #Sepsis, #ColonCancer, #HIV, #PalliativeCare, #Autism, #TB, #HeartFailure, and much more with our editorial on social media bans for young people

…all available #OpenAccess❗️

Read more here: www.thelancet.com/issue/S2589-...

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New review article

Global perspective on gaps in fungal diagnostics in low-resource settings: WHO landscape analysis and research priorities for invasive fungal diseases

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#IDSky #ClinMicro #MycoSky #OpenAccess #OA

New research article

Serotype-specific pneumococcal invasiveness: a global meta-analysis of paired estimates of disease incidence and carriage prevalence

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#IDSky #ClinMicro #Streptococcus #IPD #OpenAccess #OA

Figure showing diagnostic and therapeutic algorithm of leprosy. Copyright: 2025 Elsevier Ltd. All rights are reserved.

Leprosy, or Hansen's disease, remains a key global health issue.

In a Seminar, authors provide an update on key public health and clinical aspects of the disease: spkl.io/63328AQzar

New research article

Efficacy and safety of #lenacapavir, #teropavimab, and #zinlirvimab: week-26 primary outcome results from a multicentre, open-label, randomised, active-controlled, phase 2 study

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#IDSky #ClinMicro #ViroSky #HIV #OpenAccess #OA

New research article

Spatiotemporal patterns of #RiftValleyFever virus in Africa: a retrospective genomic epidemiology and phylodynamic modelling study

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#IDSky #ClinMicro #ViroSky #RVFV #OpenAccess #OA

New research article

#Bedaquiline resistance in patients with Xpert MTB/RIF Ultra-tested #rifampicin resistant #tuberculosis in the Western Cape, South Africa: a prospective study

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#IDSky #ClinMicro #TBSky #TB #AMR #OpenAccess #OA