Nicole Krentz πŸ‡¨πŸ‡¦'s Avatar

Nicole Krentz πŸ‡¨πŸ‡¦

@nkrentz

Diabetes researcher at the University of British Columbia

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31.10.2023
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Latest posts by Nicole Krentz πŸ‡¨πŸ‡¦ @nkrentz

It’s an honor to be a candidate for @endosocjournals.bsky.social President-Elect, and to have the opportunity to advocate for patients, physicians, and scientists in #Endocrinology around the world.

Voting is open until March 4: bit.ly/4qdrySB

08.01.2026 23:33 πŸ‘ 8 πŸ” 2 πŸ’¬ 0 πŸ“Œ 0
#4 Islets in a Pod with Dr. Andrew Pepper
#4 Islets in a Pod with Dr. Andrew Pepper YouTube video by CIRTN-R2FIC

Happy New Year ! πŸŽ† We hope everyone had a wonderful winter holiday.
We have uploaded our fourth Islets in a Pod episode. Here we interview Dr. Andrew Pepper from the University of Alberta.
youtu.be/Z2i0-C0KkaU

06.01.2026 04:43 πŸ‘ 4 πŸ” 3 πŸ’¬ 0 πŸ“Œ 0

Merry Christmas, Adelaide and Percy! Wishing you a restful winter break and a calmer 2026.

25.12.2025 16:06 πŸ‘ 1 πŸ” 0 πŸ’¬ 0 πŸ“Œ 0

Our latest now published in @natcomms.nature.com, where we found a new role for mitochondrial programming of SC-Ξ² cell fate through PPARΞ±.

We're excited for the potential to target mitochondria to improve SC-islets to treat #T1D!

www.nature.com/articles/s41...

12.12.2025 16:33 πŸ‘ 27 πŸ” 11 πŸ’¬ 1 πŸ“Œ 0

⚽️🌴

06.12.2025 21:28 πŸ‘ 0 πŸ” 0 πŸ’¬ 0 πŸ“Œ 0
Two women smiling at Chase Stadium for Miami v Vancouver MLS cup match.

Two women smiling at Chase Stadium for Miami v Vancouver MLS cup match.

Woman holding Vancouver scarf at Chase Stadium for Miami v Vancouver MLS cup match.

Woman holding Vancouver scarf at Chase Stadium for Miami v Vancouver MLS cup match.

Hey Mom, wanna do something spontaneous?

06.12.2025 19:17 πŸ‘ 6 πŸ” 0 πŸ’¬ 1 πŸ“Œ 0

🧡(1/12) November is Diabetes Awareness Month, and we have many works coming out from the CIRTN labs focusing on islet biology and diabetes. For the beginning of Nov 2025, we have papers from Drs Thompson, Verchere, Chen, Dhanvantari, Hill, Hoesli, Kin, Levings, Lynn, Riddell, Rutter and Wheeler.

17.11.2025 23:26 πŸ‘ 12 πŸ” 7 πŸ’¬ 1 πŸ“Œ 0
#1 Islets in a Pod with Dr. Patrick MacDonald
#1 Islets in a Pod with Dr. Patrick MacDonald YouTube video by CIRTN-R2FIC

CIRTN-R2FIC is currently running in Toronto its 4th Annual Meeting. During this meeting we have launched our mini interview series called "Islets in a Pod" ! Our first interview is with Dr. Patrick MacDonald from the University of Alberta.
youtu.be/UlHn_1Fz3ck?...

25.11.2025 16:00 πŸ‘ 18 πŸ” 14 πŸ’¬ 1 πŸ“Œ 1
Preview
Associate Professor (tenure) or Professor (tenure) Dr. Connie Eaves Chair in Cancer Stem Cell Research Academic Job Category Faculty Bargaining Job Title Associate Professor (tenure) or Professor (tenure) Dr. Connie Eaves Chair in Cancer Stem Cell Research Department School of Biomedical Engineering | ...

Apply for the 'Dr. Connie Eaves Chair in Cancer Cell Research' at UBC. Come join the dynamic research community in Vancouver πŸ‡¨πŸ‡¦!

18.11.2025 23:52 πŸ‘ 5 πŸ” 9 πŸ’¬ 1 πŸ“Œ 1
a schematic of pancreatic beta and delta cells that explains how they turn glucose into activation and how these cell types signal to each other via gap junctions and G protein coupled receptors. The image has two stills of islet cells expressing fluorescent sensors for calcium and cAMP and of the same islet cells stained for the presence of the hormones insulin and somatostatin.

a schematic of pancreatic beta and delta cells that explains how they turn glucose into activation and how these cell types signal to each other via gap junctions and G protein coupled receptors. The image has two stills of islet cells expressing fluorescent sensors for calcium and cAMP and of the same islet cells stained for the presence of the hormones insulin and somatostatin.

Very proud to see the main thesis work of the intrepid Dr. Mohammad Pourhosseinzadeh come out in @pnas.org today! In this paper, Mohammad assesses how crosstalk between insulin-secreting beta and somatostatin-secreting delta cells in the islet actually happens, in near real-time. A quick thread 1/10

16.09.2025 21:21 πŸ‘ 23 πŸ” 6 πŸ’¬ 4 πŸ“Œ 0

Hello! Welcome to the CIRTN-R2FIC BlueSky account! Our group focuses on researching pancreatic islet biology and pathology related to islets such as type 1 and type 2 diabetes.
Here you will find bi-weekly updates from the scientists from across Canada that make up CIRTN-R2FIC.

12.09.2025 21:12 πŸ‘ 16 πŸ” 16 πŸ’¬ 1 πŸ“Œ 0
Careers | Department of Cellular & Physiological Sciences

Our department at The University of British Columbia in Vancouver (Canada) is running two faculty searches. One is a joint hire with the Institute for Healthy Aging, one a cohire with the Math Dept cps.med.ubc.ca/careers-2/ Click on β€œFaculty Positions” on the page. Please help spread the word!

30.07.2025 17:11 πŸ‘ 35 πŸ” 41 πŸ’¬ 1 πŸ“Œ 3
Edmonton

Edmonton

Official posting coming soon, but here's a heads-up:

#Postdoc Opportunity for individuals with an interest in advancing the understanding of pancreatic islet hormones in health and #diabetes. Diverse backgrounds, skill sets and experiences are welcome!

www.bcell.org

24.07.2025 22:00 πŸ‘ 14 πŸ” 16 πŸ’¬ 1 πŸ“Œ 2

Bringing this thread back since this paper is currently featured as the Endocrinology Article of the Week! πŸŽ‰This paper was the result of years of hard work during my PhD and it wouldn't have been possible without the excellent mentorship from Francis and the collaborative efforts of all co-authors.

15.07.2025 18:08 πŸ‘ 16 πŸ” 4 πŸ’¬ 0 πŸ“Œ 0
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We are launching a new initiative to support experimental design, data management/analysis and bioinformatics. Early days yet, but check it out here.

www.bcell.org/adi-datasci....

08.07.2025 22:01 πŸ‘ 13 πŸ” 11 πŸ’¬ 1 πŸ“Œ 0

Come join us in Vancouver! Exciting opportunity for a more senior investigator researching new regenerative medicine approaches for Type 1 diabetes. $8M in funding for successful candidate research.ubc.ca/media/file/j...

07.07.2025 20:07 πŸ‘ 34 πŸ” 32 πŸ’¬ 0 πŸ“Œ 1

It was a pleasure to be able to contribute to this paper on a novel cause of transient neonatal diabetes. Check it outπŸ‘‡πŸ»

03.07.2025 15:31 πŸ‘ 5 πŸ” 0 πŸ’¬ 0 πŸ“Œ 0
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Homozygous loss-of-function variants in PAX4 are a novel genetic cause of transient neonatal #diabetes www.sciencedirect.com/science/arti...

03.07.2025 00:22 πŸ‘ 6 πŸ” 4 πŸ’¬ 0 πŸ“Œ 0

I will be opening my new lab in September at UBC! if you’re coming to #Worm25 and are looking for graduate studies or a postdoc position, let’s meet! Vancouver + worms = perfect vibes. www.zoology.ubc.ca/~yeecs/labsi... Please share! πŸ™Œ

25.06.2025 13:48 πŸ‘ 52 πŸ” 26 πŸ’¬ 3 πŸ“Œ 1

Woo hoo! Congratulations Dr Biswas πŸŽ‰

11.06.2025 05:05 πŸ‘ 1 πŸ” 0 πŸ’¬ 0 πŸ“Œ 0

Pharmacological targeting of SOS1-RAS interaction triggers pancreatic Ξ²-cell proliferation and sustainably reverses diabetic hyperglycemia https://www.biorxiv.org/content/10.1101/2025.06.03.657628v1

04.06.2025 05:30 πŸ‘ 0 πŸ” 2 πŸ’¬ 0 πŸ“Œ 1
Jelena Kolic

I'm very excited to share that I'll be starting as an Assistant Professor at the University of Alberta this fall πŸŽ‰ !!

I'm very grateful to mentors, colleagues, friends, and family who have supported me along the way ❀️.

www.ualberta.ca/en/physiolog...

02.06.2025 17:28 πŸ‘ 69 πŸ” 6 πŸ’¬ 10 πŸ“Œ 0

Congratulations, FL! A well-deserved recognition of your continued success as a researcher, teacher, mentor, and leader. πŸ₯³πŸŽ‰

27.05.2025 19:42 πŸ‘ 3 πŸ” 0 πŸ’¬ 1 πŸ“Œ 0

A lifespan of 75 years 😒

24.05.2025 16:20 πŸ‘ 2 πŸ” 0 πŸ’¬ 0 πŸ“Œ 0
Preview
Improving cellular fitness of human stem cell-derived islets under hypoxia - Nature Communications Hypoxia impairs the efficacy of stem cell-derived islet cell therapy, making it a potential barrier for treatment of type 1 diabetes. Wang et al. identify EDN3 as a key factor that preserves Ξ² cell id...

Wang et al. show that, unlike other stem cell-derived endocrine cells, there is a progressive loss of cell identity and metabolic function in stem cell-derived Ξ² cells when exposed to hypoxia. πŸ§ͺ
#PancSky

www.nature.com/articles/s41...

23.05.2025 05:29 πŸ‘ 5 πŸ” 3 πŸ’¬ 1 πŸ“Œ 0

Congratulations, @annagloyn.bsky.social! A very well-deserved recognition of a brilliant scientist and mentor πŸŽ‰

23.05.2025 03:18 πŸ‘ 2 πŸ” 0 πŸ’¬ 1 πŸ“Œ 0
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Thrilled to announce a major milestone for our lab @ifibyne @Exactas_UBA β€” our paper on the glucocorticoid receptor's role in early pancreas development is now published in @Dev_journal!
Huge thanks to @vallierlab.bsky.social for this long-term collaboration!πŸ‘‡πŸ§΅
πŸ”— doi.org/10.1242/dev....

15.05.2025 19:27 πŸ‘ 8 πŸ” 3 πŸ’¬ 2 πŸ“Œ 5
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New study from @mayoclinic.org uses #stemcells to model diabetic alpha cell dysfunction. SC-Ξ± cells mimic glucagon hypersecretion and sunitinib (tyrosine kinase inhibitor) protects against ER stress-induced dysfunction
ow.ly/CWmV50VPsVt
@isscr.org @gairdnerawards.bsky.social @sickkidsvs.bsky.social

08.05.2025 19:48 πŸ‘ 5 πŸ” 2 πŸ’¬ 0 πŸ“Œ 0
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Excited to announce our newest #Immunology recruitment πŸŽ‰πŸ₯³

This is for a Canada Research Chair (Tier 1)πŸ‡¨πŸ‡¦, a position that isnt offered often when 7yr term incl full salary (+renewable)!

Please share widely when broad immunology focus. Happy to answer any dept Q & note date πŸ‘‡
@umanitoba.bsky.social

01.05.2025 20:49 πŸ‘ 9 πŸ” 13 πŸ’¬ 0 πŸ“Œ 0
Preview
NPAS4 depletion in POMC neurons protects from obesity and alters the feeding-regulated transcriptome in male mice Abstract. Immediate Early Genes (IEGs), such as Neuronal PAS domain protein 4 (Npas4), are induced as part of the response to environmental stimuli. In the

Thrilled to share our latest work, which was the outstanding doctoral work of @samanthajsyoon.bsky.social academic.oup.com/endo/advance... 1/12

29.04.2025 19:24 πŸ‘ 32 πŸ” 13 πŸ’¬ 1 πŸ“Œ 1