Many thanks to you and @annechevallereau.bsky.social for hosting me in Lyon - great company, great discussions, and a great city! 🇫🇷🧬🚀
10.03.2026 10:44
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Many thanks to you and @annechevallereau.bsky.social for hosting me in Lyon - great company, great discussions, and a great city! 🇫🇷🧬🚀
We found a viral Trojan Horse: a virus can hide inside another virus.This one surprised us: deltaviruses don’t just borrow a helper virus. They can travel inside it.
A literal Trojan Horse “virus-in-a-virus” route into cells. 🤯 Kudos to 1st author @viroscope.bsky.social and co-authors !
New preprint of our friend Aritz Roa @aritz-roa.bsky.social with Nicholas Taylor @nmitaylorlab.bsky.social - even if phage mechanics are not your thing, check out their MAGNIFICENT video of T4 host recognition + infection directly im the post! 🎬🧬🔥
🚨Preprint! Happy to share the research from my PhD “Genome delivery of a contractile tailed phage and its superinfection exclusion mechanism”. We use cryoEM to study the genome ejection of the phage T4, revealing how the tape measure protein regulates the process.
www.biorxiv.org/content/10.6...
After >10 years of our lab studying bacterial cGAS-like enzymes, @hobbslabutah.bsky.social finally reconstitutes viral sensing in vitro and discovers how these ancient receptors sense phage protease enzymes to detect virion assembly and activate antiviral immunity
www.biorxiv.org/content/10.6...
Convergent MurJ flippase inhibition by phage lysis proteins www.nature.com/articles/s41...
4am today - Morgestraich! Lights out, lanterns on: Basler Fasnacht begins. 🎭🥁🌠
Another cross-country trip (for a doctoral defense) - quiet office time with a view! 🚆🌊❄️
Excited to share our preprint on integrase directionality here.
www.biorxiv.org/content/10.1...
Figure from: Can ecological interactions drive evolutionary outcomes? Evidence from insect host shifts between pa
A tribe of weevils has cracked a rare evolutionary puzzle: shifting hosts between parasitic and non-parasitic plants across distantly related families. Phylogenomic analysis reveals how plant-plant parasitism creates unique opportun...
https://www.biorxiv.org/content/10.1101/2024.04.03.587887
It's not even carnival yet and feels like spring already ☀️🌇
Did not look for phages im this course, but the students found some interesting enterobacteria in different food items... curious what their genomes will show 🪄🧬
Possibly, yes! But it is something people may not think about (me included) when using dried herbs / spices in a way that enables replication of those CFUs...
This was a sample of dill, I think...
Many thanks to Dr. Markus Schuppler, Carmen Saez, and Christian Gübeli for implementation of the course. We have to do it twice in a row because it's so popular!
Reality check at the food microbiology practical course - molds from a sample of dried herbs... 🧫🍂
@contamclub.bsky.social
First events of our initiative debating access to phage therapy in Switzerland took place in Basel over the last weeks - great and constructive debates with the people as well as politicians, patients, clinicians, and regulators!
Together we can make things happen. 🇨🇭🧬🌟
It seems that NCBI GenBank is currently not active beyond the repository itself and has also been unresponsive to requests for a while already.
Do you think this may be a transient inconvenience or a sign that we should explore alternatives such as ENA at EMBL-EBI?
Making the home office more social - lunch in the city with university friends 🍝🏙
Can also be nice, if the trains are going and are kind-of in time....
Spent most of my working day on silent + comfortable trains and I have rarely been more productive... also: Sunshine in Lausanne! ☀️🧬🇨🇭
🍄Transposon traffic in the mycocosmos🍄
Fascinating work reveals extensive horizontal TE transfer across fungi (@jromeijn.bsky.social, Iñigo Bañales & @mfseidl.bsky.social; doi.org/10.1016/j.cu...). I wrote a Dispatch to prime non-specialists,check it out here: doi.org/10.1016/j.cu....
#TEworldwide
Happy to share our recent preprint:
"DNA-intercalating antiphage molecules trigger abortive infection through mutual destruction and synergize with bacterial immunity"
www.biorxiv.org/content/10.6...
@spp2330.bsky.social, @mibinet.bsky.social, @dfg.de @hhu.de @fzj.bsky.social
Massive revision to our paper on relaxed selection of male reproductive genes in gorillas. TL;DR, they are eroding away coincident with the shift to polygyny in gorillas; big bodies no need for good sperm. 🦍 🤷 🧪 #EvoBio #SpermCompetition
www.biorxiv.org/content/10.1...
Secret life of prophages: template-directed synthesis of DNA superstructures via prophage activation and rolling circle replication in bacterial biofilms
bioRxiv by Gabriel Antonio S. Minero et al
with @thethormannden.bsky.social, Rikke Louise Meyer
www.biorxiv.org/content/10.6...
Happy new year to everybody - let's make it a good one (though the world seems to be seriously off track...)! 🌟🎉🧬
IMO knowing when to drop (even temporarily) a project is the hardest thing to navigate as a PI. It depends on so many variables, a lot of them unrelated to the actual science. The call is by definition made with incomplete information - deciding when high risk, high gain is just too risky
This story is absolutely wild. Did you know that avocados change sex over the course of a day? And that it's controlled by a single ancient balanced polymorphism? This is flat our crazy
Cold walks and warm delicacies - merry Christmas to all! 🎅🏼🍻
