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VastDB

@vastdb

VastDB is a repository of quantitative profiles of alternative splicing events and GE data across different tissues and species. Developed at @CRGenomica. Website: https://t.co/gOCIXBbxcO

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12.11.2024
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Latest posts by VastDB @vastdb

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🚨🧬🚨

We're looking for a specialized Research Assistant to spearhead a project aimed at exploring new RNA therapeutics in diabetes and other metabolic disorders.

Junior or Senior, we're hoping to recruit a highly motivated and self-driven scientist interested in both basic and applied science. πŸ¦„

02.03.2026 16:07 πŸ‘ 7 πŸ” 11 πŸ’¬ 0 πŸ“Œ 0
Dario Valenzano at PRBB

Dario Valenzano at PRBB

Today we had a great EvoMG Seminar by Dario Valenzano @dvalenzano.bsky.social from FLI, who told us about some of their recent aging work using the fascinating short-lived killifish.

Hosted by @mirimiam.bsky.social

evomedgenomics.com/events/exter...

05.11.2025 23:18 πŸ‘ 11 πŸ” 5 πŸ’¬ 0 πŸ“Œ 0

Last days to apply! Cool project, cool cities! :-)

(Please repost! πŸ™)

22.09.2025 07:04 πŸ‘ 12 πŸ” 16 πŸ’¬ 0 πŸ“Œ 0
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Happy to share the Biodiversity Cell Atlas white paper, out today in @nature.com. We look at the possibilities, challenges, and potential impacts of molecularly mapping cells across the tree of life.
www.nature.com/articles/s41...

24.09.2025 15:12 πŸ‘ 228 πŸ” 106 πŸ’¬ 4 πŸ“Œ 10

🚨🚨🚨 New review article on #microexons from the lab! A comprehensive recap of the current state of the field by @tahneema.bsky.social.

www.annualreviews.org/content/jour...

01.09.2025 10:19 πŸ‘ 15 πŸ” 3 πŸ’¬ 0 πŸ“Œ 1

🚨🚨🚨

Please RT!

We're looking for a postdoc to join an exciting joint project between our lab @upf.edu & @crg.eu (Barcelona) and the Sander lab @mdc-berlin.bsky.social (Berlin) investigating how alternative splicing and microexons influences the maturation of pancreatic islets.

Deadline: 30/09/25πŸ‘‡

23.07.2025 14:27 πŸ‘ 48 πŸ” 65 πŸ’¬ 1 πŸ“Œ 3
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Cotyledon opening during seedling deetiolation is determined by ABA-mediated splicing regulation | EMBO reports imageimageAbscisic acid (ABA) prevents cotyledon opening in the dark by modulating splicing through serine/arginine-rich (SR) proteins RS40 and RS41. Light reduces ABA levels, releasing this repressio...

www.embopress.org/doi/full/10....

19.06.2025 15:38 πŸ‘ 1 πŸ” 0 πŸ’¬ 0 πŸ“Œ 0
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"The main fates after gene duplication are gene loss, redundancy, subfunctionalization and neofunctionalization".

In our new review, @fedemantica.bsky.social and I argue we are missing the most prevalent one: specialization. And the same applies to alternative splicing! 1/7

tinyurl.com/45k7kbmp

18.03.2025 13:53 πŸ‘ 41 πŸ” 16 πŸ’¬ 2 πŸ“Œ 1

The job call is officially open. If you're interested, please apply through this link ASAP! πŸ˜ƒ

www.mdc-berlin.de/career/jobs/...

Please RT! πŸ™

21.01.2025 17:25 πŸ‘ 15 πŸ” 23 πŸ’¬ 0 πŸ“Œ 0
Phenotypic impact of individual conserved neuronal microexons and their master regulators in zebrafish

🐟 Our new paper "Phenotypic impact of individual conserved neuronal microexons and their master regulators in zebrafish" is out in @elife.bsky.social 🐟

A nearly 10-year tour-de-force by Laura Lopez-Blanch and many others in the lab @crg.eu & @upf.edu

elifesciences.org/reviewed-pre...

Thread πŸ‘‡1/9

30.12.2024 16:07 πŸ‘ 32 πŸ” 15 πŸ’¬ 2 πŸ“Œ 0
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🚨🚨🚨

If you're a bioinformatician who loves:

🧬 #SingleCell #LongReadSequencing & #AlternativeSplicing
πŸš€ Collaborating and travelling

Apply to work with us at the spectacular BIMSB (@mdc-berlin.bsky.social) in Berlin + @upf.edu-@crg.eu in Barcelona. Qs: www.transdevolab.com

Please RT! πŸ™

23.12.2024 15:54 πŸ‘ 25 πŸ” 28 πŸ’¬ 0 πŸ“Œ 1
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We’re recruiting a PhD student to use comparative omics to investigate why some viruses can efficiently infect both human and mosquito cells, but lead to different infection outcomes. Fully funded position by @evomg-bcn.bsky.social at our lab at UPF-CRG and the Diez lab.

www.crg.eu/en/content/t...

10.12.2024 11:33 πŸ‘ 23 πŸ” 22 πŸ’¬ 0 πŸ“Œ 1
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Paso adelante en la genΓ©tica del autismo El descubrimiento del mecanismo que podrΓ­a explicar un gran porcentaje de los trastornos del espectro autista es un recordatorio de la importancia de apoyar la investigaciΓ³n espaΓ±ola

"La importancia de apoyar la investigaciΓ³n en EspaΓ±a"
πŸ‘πŸ‘πŸ‘
elpais.com/opinion/2024...

11.12.2024 13:17 πŸ‘ 1 πŸ” 1 πŸ’¬ 0 πŸ“Œ 0
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Investigadores espaΓ±oles dan un paso mΓ‘s en descifrar el misterio del autismo El trabajo, publicado en 'Nature', explica por quΓ© la pΓ©rdida de ocho aminoΓ‘cidos de cientos de una proteΓ­na tiene un "efecto tan fuerte" en el neurodesarrollo y abre nuevas vΓ­as para desarrollar tera...

β€Ό Investigadores espaΓ±oles dan un paso mΓ‘s en descifrar el misterio del autismo

04.12.2024 16:10 πŸ‘ 158 πŸ” 44 πŸ’¬ 2 πŸ“Œ 9
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The 24 DNA letters linked to autism: GCAAGGACATATGGGCGAAGGAGA A team of Spanish scientists has discovered the mechanism that could explain a high percentage of autism spectrum disorders

Who would have thought that an actual sequence of a #microexon (GCAAGGACATATGGGCGAAGGAGA from CPEB4) would be in the headline of an article in @elpais.com! Congrats to the Mendez, @xsalvatella1.bsky.social and @jjlucaslab.bsky.social labs for this amazing work!

english.elpais.com/science-tech...

05.12.2024 11:50 πŸ‘ 35 πŸ” 6 πŸ’¬ 1 πŸ“Œ 1