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Goh Zhang-He

@goh-zhanghe

#chemist at A*STAR Singapore | previously a Pharmacy graduate #preLighter at #preLights Views my own Like =/= endorse

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Latest posts by Goh Zhang-He @goh-zhanghe

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a penguin with a bandana on his head says " don 't worry i 'm a doctor " in white letters ALT: a penguin with a bandana on his head says " don 't worry i 'm a doctor " in white letters

For the next 24h, drop any infectious disease and/or vaccine-related questions in response to this post, and I will do my best to answer them. Answers are for information only, NOT medical advice.
#AskAnIDDoc March 2026 edition.

07.03.2026 13:15 ๐Ÿ‘ 266 ๐Ÿ” 87 ๐Ÿ’ฌ 52 ๐Ÿ“Œ 14
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The LCSO research website has been updated with our last results: Have a look to learn more about our research from 2007 to 2026! Overview: https://lnkd.in/eWEtDkMR Electrophilic alkynylation:โ€ฆ | LCS... The LCSO research website has been updated with our last results: Have a look to learn more about our research from 2007 to 2026! Overview: https://lnkd.in/eWEtDkMR Electrophilic alkynylation: https:...

The LCSO research website has been updated!
www.linkedin.com/feed/update/...

11.03.2026 12:17 ๐Ÿ‘ 5 ๐Ÿ” 1 ๐Ÿ’ฌ 0 ๐Ÿ“Œ 0

4/n

Alas, it had gotten caught in a spider's web, and the spider (much smaller than the bee, by the way!) was busy packaging dinner

the circle of life!

/end

09.03.2026 22:30 ๐Ÿ‘ 0 ๐Ÿ” 0 ๐Ÿ’ฌ 0 ๐Ÿ“Œ 0

3/n

several minutes later, the bumblebee's buzzes had changed.

out of curiosity i headed over the window to have a look at what was happening--perhaps it had landed on some of the plants in the house?

09.03.2026 22:30 ๐Ÿ‘ 0 ๐Ÿ” 0 ๐Ÿ’ฌ 1 ๐Ÿ“Œ 0

2/n

i opened another window hoping it would fly out

09.03.2026 22:30 ๐Ÿ‘ 0 ๐Ÿ” 0 ๐Ÿ’ฌ 1 ๐Ÿ“Œ 0

reminds me of the time i was bashing out my #PhD thesis

a friendly bumblebee came to visit and didn't really know how to get out of the house

1/n

09.03.2026 22:30 ๐Ÿ‘ 2 ๐Ÿ” 0 ๐Ÿ’ฌ 1 ๐Ÿ“Œ 0
Downing College, Cambridge, depicted in pastel 1999

Downing College, Cambridge, depicted in pastel 1999

Pastel of Downing College, Cambridge.

09.03.2026 14:26 ๐Ÿ‘ 992 ๐Ÿ” 78 ๐Ÿ’ฌ 23 ๐Ÿ“Œ 2

broke: You only live once

woke: Dont be so careful in time of death

09.03.2026 14:43 ๐Ÿ‘ 2 ๐Ÿ” 1 ๐Ÿ’ฌ 0 ๐Ÿ“Œ 0
Oleksandr Zhurakovskyi site

Not the kovsky.net Reference Resolver? ๐Ÿ˜„

08.03.2026 11:01 ๐Ÿ‘ 8 ๐Ÿ” 2 ๐Ÿ’ฌ 2 ๐Ÿ“Œ 0

Requiring linkable doi's in papers' reference lists 1) increases findability of refs & 2) decreases friction to uncovering the fake refs everyone's talking about. Latter is merely a technical solution to a moral/systemic issue, but still: many benefits and trivial to implement from ref managers ๐Ÿงช

08.03.2026 09:20 ๐Ÿ‘ 46 ๐Ÿ” 2 ๐Ÿ’ฌ 4 ๐Ÿ“Œ 1

i also really enjoyed #Nimona (2023 film) and #Arcane (2021 TV series)

08.03.2026 13:50 ๐Ÿ‘ 1 ๐Ÿ” 0 ๐Ÿ’ฌ 0 ๐Ÿ“Œ 0

Meanwhile, an animated movie that is DEEPLY, undeniably tied to Korean culture went to streaming last year and had the kind of cultural impact Disney hasnโ€™t had since Frozen.

Good movies are good movies. They break through. Donโ€™t fucking blame โ€œidentitiesโ€ for your own poor storytelling.

08.03.2026 00:39 ๐Ÿ‘ 21 ๐Ÿ” 2 ๐Ÿ’ฌ 1 ๐Ÿ“Œ 1
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Disney Needs Its Next Hit Franchise. Can Pixarโ€™s Reluctant Leader Deliver? The โ€˜Toy Storyโ€™ studio used to print money for Disney but hasnโ€™t made an original blockbuster in nearly a decade. Its top creative executive admits heโ€™s made mistakes.

www.wsj.com/business/med...

08.03.2026 00:16 ๐Ÿ‘ 25 ๐Ÿ” 6 ๐Ÿ’ฌ 1 ๐Ÿ“Œ 1

oh... truly disappointing take from Pete Docter ๐Ÿ˜ž

08.03.2026 13:45 ๐Ÿ‘ 0 ๐Ÿ” 0 ๐Ÿ’ฌ 0 ๐Ÿ“Œ 0
A striking photo of seven stags against a grey sky behind them, walking across the top of a grassy hill in a line

A striking photo of seven stags against a grey sky behind them, walking across the top of a grassy hill in a line

These deer silhouetted against the sky make for quite a magical sight โœจ

They were spotted making their way through the parkland at Wentworth Castle Gardens.

๐Ÿ“ท: Amelia Webb

07.03.2026 08:01 ๐Ÿ‘ 161 ๐Ÿ” 14 ๐Ÿ’ฌ 0 ๐Ÿ“Œ 0

cant believe one year ago i was still writing my #PhD #chemsky thesis and was under so much pressure to submit by May 2025

time flies. i miss the #UK

06.03.2026 13:11 ๐Ÿ‘ 1 ๐Ÿ” 0 ๐Ÿ’ฌ 0 ๐Ÿ“Œ 0

TIL @researchrabbit.ai underwent a huge revamp?

it looks different from how it used to, did anyone else on #Sciencesky notice this change?

#chemsky

06.03.2026 10:27 ๐Ÿ‘ 1 ๐Ÿ” 0 ๐Ÿ’ฌ 0 ๐Ÿ“Œ 0

i am once again asking #EndNote to allow users to be able to change the sync options, e.g. sync more or less frequently than the default of 15 minutes

06.03.2026 10:10 ๐Ÿ‘ 1 ๐Ÿ” 0 ๐Ÿ’ฌ 0 ๐Ÿ“Œ 0

Once a chemist, always a chemist, I guess. I suppose thatโ€™s #Chemsky right thereโ€ฆ

05.03.2026 09:27 ๐Ÿ‘ 18 ๐Ÿ” 1 ๐Ÿ’ฌ 4 ๐Ÿ“Œ 5

2/2

wonder what it could have been and what makes it so special? perhaps a migratory bird or other rare find?

05.03.2026 12:47 ๐Ÿ‘ 1 ๐Ÿ” 0 ๐Ÿ’ฌ 0 ๐Ÿ“Œ 0

just saw someone taking photos of a bird standing in a field ๐Ÿ˜ฎ

it was a brown bird that looked a bit like a heron, egret, crane, stork, or other (sorry, i'm not a bird enthusiast).

#birding #Singapore

1/2

05.03.2026 12:47 ๐Ÿ‘ 1 ๐Ÿ” 0 ๐Ÿ’ฌ 1 ๐Ÿ“Œ 0

Cambridge Libraries Survey is open until Friday 27th March. Your libraries, your views!

02.03.2026 10:12 ๐Ÿ‘ 1 ๐Ÿ” 1 ๐Ÿ’ฌ 0 ๐Ÿ“Œ 0

๐Ÿงช This bacterial strain has been maintained in sterile water since 1994.

Possible carbon sources incl. โ€œphthalic acid - a plastic degradation product likely leached from inoculation tubesโ€œ.

Genomic variations accumulated between 1994 and 2022 suggested adaptations to long-term nutrient deprivation

07.02.2026 06:47 ๐Ÿ‘ 35 ๐Ÿ” 15 ๐Ÿ’ฌ 1 ๐Ÿ“Œ 1

2/2

there were four vials of this, it looked like it was to be reconstituted and injected (either bolus or continuously infused)

anyone from #pharmsky take a stab at what medication this might be?

28.02.2026 02:40 ๐Ÿ‘ 1 ๐Ÿ” 0 ๐Ÿ’ฌ 0 ๐Ÿ“Œ 0

in a hospital i once saw several vials of an evil-looking* solid

* specifically looks like solid iodine: a dark mauve solid full of crystals which looked like they were melting down the side of the vials

1/2

28.02.2026 02:40 ๐Ÿ‘ 1 ๐Ÿ” 0 ๐Ÿ’ฌ 1 ๐Ÿ“Œ 0
Post image Post image

'Panic buying' and related crisis behaviour is in the news again.

Here are some slides from my recent presentation on the topic.

www.theguardian.com/food/2026/fe...

25.02.2026 12:04 ๐Ÿ‘ 12 ๐Ÿ” 6 ๐Ÿ’ฌ 1 ๐Ÿ“Œ 0
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Our, Uh, Friends the Retroviruses

What were once vices are now. . . essential for human reproduction, apparently. Ancient retroviral sequences put to use:

12.02.2026 19:31 ๐Ÿ‘ 22 ๐Ÿ” 6 ๐Ÿ’ฌ 2 ๐Ÿ“Œ 1
Sub-stoichiometric peptide synthesis | ChemRxiv Solid-phase peptide chemistry is more than sixty years old. Its advent revolutionized peptide science. Innovation has increased safety and expanded the range of chemistries available to the practitioner, but the fundamental basis of the technology, the ...

#ChemSky

I don't promote all our papers on here...like they are ALL AWESOME (of course they are, I wrote them, and you should be honoured to have access to my GREAT THOUGHTS) but this one is a bit special. And has broad implications.

doi.org/10.26434/che...

โš—๏ธ๐Ÿ“œ๐Ÿงต

25.02.2026 16:58 ๐Ÿ‘ 18 ๐Ÿ” 7 ๐Ÿ’ฌ 1 ๐Ÿ“Œ 0

3/3

"Rather, my point is that chemists often stop trying to improve affinity once nanomolar levels have been achieved. While such levels are often sufficient, additional affinity may dramatically simplify the multi-parameter optimization process"

25.02.2026 23:59 ๐Ÿ‘ 0 ๐Ÿ” 0 ๐Ÿ’ฌ 0 ๐Ÿ“Œ 0

2/3

and from the preprint itself (www.preprints.org/manuscript/2... )

25.02.2026 23:59 ๐Ÿ‘ 0 ๐Ÿ” 0 ๐Ÿ’ฌ 1 ๐Ÿ“Œ 0