@andreaserio
Scientist, Gamer, Geek, Sci-Fi and Fantasy Nerd, Comic Book Reader, Dad, First of His Name and collector of useless-but-wonderful facts. Head of the Neural Circuit Bioengineering group @ King's College London & The Francis Crick Institute. PI @ UK DRI
5/5
Developed over the last 7 years by our team @TheCrick & @KingsIoPPN,
VISIBLE is customisable, modular, and pushing boundaries in tissue engineering, neuroscience & cancer biology. Sounds interesting? Get in touch
📄 doi.org/10.1101/2025...
#VISIBLE #Organoids #Bioprinting #LabAutomation
4/5
Why it matters:
✅ Imaging-driven decisions
✅ Precision cell manipulation
✅ Real-time experimental feedback
✅ Adaptable to many workflows
VISIBLE turns dynamic cultures from unpredictable to programmable 🔁
3/5
What can it do?
📍 Target organoids by shape, markers, or calcium activity
🧠 Sample neurospheres based on functional maturity
🖨️ Bioprint cell-laden hydrogels with pause/scan/resume
💥 Automate scratch assays
🧬 Implant barcoded PDXOs for in vivo tracing
2/5
VISIBLE combines:
🔬 Live fluorescence imaging
🤖 Robotic manipulation
🖨️ Interactive 3D bioprinting
🌡️ Enclosed incubation
All in one modular, feedback-controlled platform — no plate transfer, full real-time control.
1/5
🚨 New bioengineering tech in our latest pre-print!
Say hello to VISIBLE — a real-time, imaging-guided system that can see, print, sample & manipulate live 3D cell cultures like organoids and neurospheres.
A powerful leap toward automation in complex biology 🔬🤖
📄 doi.org/10.1101/2025...