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Mark Levin

@levinchem

Professor of Chemistry University of Chicago Single-Atom Skeletal Editing (Interspersed with doomposting and AI skepticism) Husband, Dad, Crossword Addict http://levingroup.uchicago.edu

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Latest posts by Mark Levin @levinchem

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Michael Ziebel and Song Lin Join Stanford Chemistry | Chemistry The Department of Chemistry is pleased to announce the forthcoming addition of two esteemed chemists to our faculty this fall.

πŸ“’ Join us in welcoming @mikeziebel.bsky.social & @songlin1.bsky.social as they join our dept. and esteemed faculty in chemistry this fall. Their contributions will further advance our mission of academic excellence and research innovation!

chemistry.stanford.edu/news/michael...

#WelcometoStanford

06.03.2026 18:29 πŸ‘ 6 πŸ” 1 πŸ’¬ 0 πŸ“Œ 0

I just renewed my membership in @aaup.org Their advocacy nationwide and the strong support of @ncaaup.bsky.social and @unc-ch-aaup.bsky.social on our campus has been a breath of fresh air in these challenging times

04.03.2026 12:22 πŸ‘ 17 πŸ” 6 πŸ’¬ 1 πŸ“Œ 1
03.03.2026 21:18 πŸ‘ 30 πŸ” 4 πŸ’¬ 5 πŸ“Œ 3

Now accepted @jacs.acspublications.org πŸ₯³

pubs.acs.org/doi/full/10....

02.03.2026 17:11 πŸ‘ 22 πŸ” 2 πŸ’¬ 0 πŸ“Œ 0
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www.organic-chemistry.org/abstracts/li...
Ξ±-Chlorodiazirines as thermal precursors to the corresponding chlorocarbenes for a synthesis of 3-(hetero)arylpyridines and quinolines

18.02.2026 09:51 πŸ‘ 3 πŸ” 1 πŸ’¬ 0 πŸ“Œ 0
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We are pleased to share that Assistant Professor Anna Wuttig has been named a 2026 Sloan Research Fellow! πŸ†

This honor from the Sloan Foundation recognizes early-career scientists with the potential to revolutionize their fields.

#UChicago #Chemistry #SloanFellow #Electrochemistry #WomenInSTEM

17.02.2026 22:17 πŸ‘ 22 πŸ” 4 πŸ’¬ 1 πŸ“Œ 1

Heart-wrenching.

13.02.2026 02:23 πŸ‘ 2 πŸ” 1 πŸ’¬ 0 πŸ“Œ 0

@merz.bsky.social I read the latest "AI is coming" manifesto by Shumer and was genuinely confused to read a prediction that was a ~year old that did not happen - and it is surprising to me that these folks don't recognize how damaging it is to their credibility

11.02.2026 23:17 πŸ‘ 15 πŸ” 2 πŸ’¬ 1 πŸ“Œ 0

This is obvious bait but ok, let's hear it

04.02.2026 03:35 πŸ‘ 3 πŸ” 0 πŸ’¬ 1 πŸ“Œ 0

At least one of those is... Definitely not a nitrile

31.01.2026 02:06 πŸ‘ 2 πŸ” 0 πŸ’¬ 0 πŸ“Œ 0

Pro-LLM academics bemoaning how long it takes to write and review papers are telling on themselves. Those tasks are supposed to take a long time because that's how you can be thoughtful, thorough, and rigorous.

Filtering yourself is how you only communicate things you think are worth reading.

29.01.2026 15:36 πŸ‘ 15 πŸ” 1 πŸ’¬ 3 πŸ“Œ 0

Publishers are already seeing unprecedented quantities of AI slop and unethical AI use by authors and reviewers, and it's terrifying that tools like this will open the floodgates further. Gen AI is a plague and I wish it a swift death.

28.01.2026 13:54 πŸ‘ 7 πŸ” 3 πŸ’¬ 0 πŸ“Œ 1

Good start www.youtube.com/watch?v=VwcK...

27.01.2026 00:56 πŸ‘ 148 πŸ” 18 πŸ’¬ 7 πŸ“Œ 1
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Gregory Bovino Gets Demoted The Border Patrol chief was the public face of a traveling immigration crackdown on cities governed by Democrats.

BREAKING Greg Bovino has been removed as Border Patrol "commander at large" and will return to El Centro Calif, where he is expected to retire soon. A stunning turnaround after Pretti killing. Bovino's traveling blue city crackdown is over www.theatlantic.com/politics/202...

26.01.2026 23:40 πŸ‘ 10481 πŸ” 3185 πŸ’¬ 1271 πŸ“Œ 3633

This is a wild story

23.01.2026 07:41 πŸ‘ 22 πŸ” 6 πŸ’¬ 5 πŸ“Œ 1
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Managing Director Department PSD Chemistry: Staff Leadership About the Department One of the first departments founded at the University of Chicago was the Department of Chemistry. Since its inception, the Department o...

The University of Chicago Department of Chemistry is currently seeking a Managing Director to Lead Department of Chemistry Operations.

Follow the link for full job description, qualifications and benefits- tinyurl.com/3p3r8rn9

15.01.2026 18:46 πŸ‘ 2 πŸ” 3 πŸ’¬ 0 πŸ“Œ 0
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Today on @chemrxiv.org, we disclose a C-to-N replacement that actually works complex natural products - a pipe-dream when we started. The secret is to lean in to the triplet nitrene.

Congrats Dong Il, and thanks to the whole team, including collaborators from Sanofi!

chemrxiv.org/engage/chemr...

13.01.2026 18:41 πŸ‘ 30 πŸ” 5 πŸ’¬ 1 πŸ“Œ 2
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I Tried to Be the Government. It Did Not Go Well. My five-month quest to monitor the weather, track inflation, and inspect milk for harmful microorganisms

if you want a long read that involves udders, a hot air balloon, and some extremely dubious data on egg prices, the story I’ve been working on for the last few months where I tried to single-handedly take on every government function myself is now online! www.theatlantic.com/magazine/202...

08.01.2026 20:41 πŸ‘ 1570 πŸ” 361 πŸ’¬ 34 πŸ“Œ 83

Considering that IMAN (4) is also in this picture, the concentrated crossword power on display here is overwhelming. Blinding. Nuclear. ☒️

08.01.2026 12:04 πŸ‘ 68 πŸ” 9 πŸ’¬ 2 πŸ“Œ 0
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The National Weather Service used AI to create a forecast for Idaho. Low chances of wind for the nonexistent towns of Cocrerrireod, Orangeotild and Whata Bod www.washingtonpost.com/weather/2026...

07.01.2026 14:32 πŸ‘ 2387 πŸ” 785 πŸ’¬ 96 πŸ“Œ 202
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Robert F. Kennedy Jr. to Be Declared Honorary Virus The ceremony will feature roadkill hors d’oeuvres, goblets of beef tallow, and a sewage plunge.

I continue to be enraged by everything the secretary of health and human services is doing www.theatlantic.com/newsletters/...

07.01.2026 16:51 πŸ‘ 489 πŸ” 102 πŸ’¬ 11 πŸ“Œ 9

is there some way I can quickly unlearn all of history so as to feel better about recent events

03.01.2026 17:59 πŸ‘ 1921 πŸ” 275 πŸ’¬ 64 πŸ“Œ 20
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Skeletal editing: How close are we to true cut-and-paste chemistry? Reactions that alter organic scaffolds by a single atom are already proving useful, but time will tell if they’ll fundamentally change how molecules are made

βœ‚οΈ July: Adventures in atom swapping!
cen.acs.org/synthesis/me...
(see also this very successful feature cen.acs.org/synthesis/Sk...)

πŸ§ͺ August: Beth Halford, Laura Howes, and I revamped C&EN's first disclosures coverage to put the molecules front and center
cen.acs.org/pharmaceutic...

31.12.2025 20:03 πŸ‘ 2 πŸ” 1 πŸ’¬ 1 πŸ“Œ 0

If you can't be bothered to actually write the peer review yourself why should the reviewee have to listen to it? Why write anything at all, ever? If you don't have enough time, fight for better working conditions instead of faking your work

05.03.2025 16:26 πŸ‘ 79 πŸ” 24 πŸ’¬ 0 πŸ“Œ 0
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Ok here it is - out of 44 FDA approvals this year, 31 are small molecules (70%), 26 of those are oral drugs (84%), 22 of them are chiral (71%). This is the largest number and percentage of chiral FDA approved molecules in a single year. Fitusiran is not a small molecule, bonus.

30.12.2025 12:56 πŸ‘ 74 πŸ” 33 πŸ’¬ 3 πŸ“Œ 1

I don't want to gush about my own paper too much but Alex did such an amazing job - this paper has everything: a huge scope including HTE demonstration from boronic acids, some really creative mechanistic experiments and a cherry-on-top computational study that helped us sort it all out. Enjoy!

30.12.2025 14:41 πŸ‘ 4 πŸ” 0 πŸ’¬ 1 πŸ“Œ 0
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Just in time for the new year - we show that you can make either isomer of N-aryl pyrazole selectively from a single TDSO. We really believe in the power of these wacky heterocycles.

chemrxiv.org/engage/chemr...

Excellent work by superstar Alex Fanourakis, in collab with Osvaldo Gutierrez and J&J

30.12.2025 14:26 πŸ‘ 27 πŸ” 3 πŸ’¬ 1 πŸ“Œ 3

I just taught my lecture course on mid-20th c US history, which starts with Harding and concludes with Nixon.

For the first time, I had to pause and stress that those scandals were actually shocking at the time and, what’s more, that Americans actually demanded people be held accountable.

27.12.2025 21:30 πŸ‘ 5215 πŸ” 1122 πŸ’¬ 90 πŸ“Œ 23

"Schools must adopt effective filters to block inappropriate or misleading content."

What filters block misleading content from ChatGPT? Is there a "no disinfo" or "no faked citations" or "no hallucinations" filter?

There is not. This is poisoned tech. You have to block the entire product.

24.12.2025 04:00 πŸ‘ 400 πŸ” 53 πŸ’¬ 1 πŸ“Œ 1

Charlie Brown also invented the alkyne zipper reaction, look it up

en.wikipedia.org/wiki/Alkyne_...

24.12.2025 21:20 πŸ‘ 7 πŸ” 1 πŸ’¬ 2 πŸ“Œ 0