Paul Nurse describing the main job of a PI
(From ‘The Thinking Game’, 2024)
31.10.2025 08:45
👍 181
🔁 53
💬 2
📌 5
I wanted my first @bsky.app post to be witty, thoughtful & somewhat self-depreciating. I wanted to make sure I could highlight all the exciting computational cancer evolution research my lab does, without sounding too arrogant. But, instead I posted this. (At least it's within the character limit.)
13.10.2025 10:13
👍 17
🔁 0
💬 0
📌 0
An excellent systematic analysis of RBPs by @quaidmorris.bsky.social and colleagues (with a tiny contribution from us) #RNAsky #RNAbiology
29.07.2025 01:41
👍 17
🔁 6
💬 0
📌 0
Fluctuating DNA methylation tracks cancer evolution at clinical scale - Nature
Cancer evolutionary dynamics are quantitatively inferred using a method, EVOFLUx, applied to fluctuating DNA methylation.
Studying cancer evolution needs multi-region or single cell seq for phylogenetics, right? Amazingly (I think!) we found single-sample bulk methylation suffices, via analysis of "fluctuating methylation". In @nature.com today led by brilliant @calumgabbutt.bsky.social www.nature.com/articles/s41...
10.09.2025 15:21
👍 91
🔁 39
💬 7
📌 2
Very excited to share our new paper on the influence of biological sex and smoking in the clonal landscape of normal human bladder, just published in Nature.
A big thank you and congrats to all the authors, specially to @raquelbmi.bsky.social for all the shared efforts in this journey!
⬇️More info⬇️
08.10.2025 18:04
👍 18
🔁 6
💬 1
📌 0
Clone copy number diversity is linked to survival in lung cancer @nature.com @zaccasimo.bsky.social @nickymcgranahan.bsky.social
www.nature.com/articles/s41...
13.08.2025 18:23
👍 4
🔁 2
💬 0
📌 0
