Kristin Kaduk

Is your brain tired? Researchers are discovering the roots of mental fatigue Better ways to measure cognitive exhaustion could point to treatments for long COVID and other debilitating disorders.

Researchers and clinicians have long struggled to define, measure, and treat cognitive fatigue. Nature reports on how scientists are enlisting innovative experimental approaches and biological markers to probe the metabolic roots and consequences of cognitive fatigue. #medsky 🧪

Thrilled to share our paper is out now in @ebiomedicine.bsky.social 🥳 The interoception accuracy part is still my favorite 🤩 Have a look: www.thelancet.com/journals/ebi...

Longitudinal studies | Grant funding | Wellcome Wellcome are funding research teams to analyse longitudinal data to help identify mental health conditions early. See eligibility information and find out how to apply.

Only a week left to apply for our Mental Health Award ⏰

We’re funding researchers to use longitudinal data to find early signs of anxiety, depression and psychosis.

Find out more and apply by 22 July ⤵️
wellcome.org/grant-fundin...

🧠✨Excited to share my work of the last year @neuromadlab.bsky.social in collaboration with @derntllab.bsky.social! Tracking 90 adults’ glucose, hunger and #mood for 4 weeks. Interesting: In our new preprint, people with lower #interoception show higher mood variability. Have a look: 👇

Summary of the study. A: The schematic shows the experimental procedure, illustrating five weekly lab visits followed by 2 MR visits labeled from S1 to S7. After the first session (S1), participants undergo four weeks of continuous glucose monitoring (CGM) combined with ecological momentary assessment (EMA). B: The CGM system uses a small flex sensor placed at the posterior upper arm that is inserted in the subcutaneous fatty tissue. The glucose sensor, positioned beneath the skin surface layers (epidermis and dermis), measures glucose levels in the interstitial fluid within the subcutaneous adipose tissue. The data is wirelessly sent via near field communication (NFC) to the FreeStyle Libre 3 app on the participant’s cell phone. The accuracy of the sensor concerning capillary glucose has been validated (Alva et al., 2022). C: Participants rate their metabolic and mood states twice daily using a visual analog scale (VAS), ranging from 0 (not at all) to 100 (very).

Do you get in a bad mood if you are hungry? Over 4 weeks with EMA+CGM, we tested if mood shifts are subconsciously driven by glucose levels or ratings of metabolic state #neuroskyence 🩺

Work w/ @kristinkaduk.bsky.social @akuehnel.bsky.social @derntllab.bsky.social

www.biorxiv.org/content/10.1...

so, so excited to share our new theory which endeavours to answer why depression and poor metabolic health go hand-in-hand: "An interoceptive model of energy allostasis linking metabolic and mental health" 💪🧠🔋 @saramehrhof.bsky.social
@hugofleming.bsky.social

osf.io/preprints/ps...

Visual target and task-critical feedback uncertainty impair different stages of reach planning in motor cortex - Nature Communications Visual uncertainty impairs reach accuracy. The authors show that uncertainty about the target always impairs cortical motor goal encoding in rhesus monkeys, while feedback uncertainty does so only whe...

🚨Paper alert! Check out our latest publication in @naturecomms.bsky.social by @lukasamn.bsky.social, Virginia Casasnovas, and Alexander Gail: "Visual target and task-critical feedback uncertainty impair different stages of reach planning in motor cortex".
www.nature.com/articles/s41...