Björn Schumacher

Outstanding keynote lectures by @rosschapmanlab.bsky.social , @karlsederlab.bsky.social , Sarah @lambertsarahlab.bsky.social, @loizoulab.bsky.social, KJ Patel, and @r-rahbari.bsky.social. Plus a lineup of fantastic speakers. Registration site: express.converia.de/frontend/ind...

Together with @spanier55.bsky.social and Boris Pfander we put together a great program with support of @cecad.bsky.social Cologne, @mpiage.bsky.social and the Fritz Thyssen Stiftung. Meeting site: www.for-5504.com/en/197/Confe...

🧬🧬🧬 REGISTRATION JUST OPENED! Make sure you join our DNA REPAIR MEETING 2026 ON PHYSIOLOGICAL CAUSES AND CONSEQUENCES OF GENOME INSTABILITY in Cologne, September 7-9, organized by the German Society for DNA Repair (DGDR) and the @dfg.de Research Unit 5504. www.for-5504.com/en/197/Confe...

Aging clocks delineate neuron types vulnerable or resilient to neurodegeneration and identify neuroprotective interventions - Nature Aging Gallrein et al. pair functional assays with clocks to compare chronological versus biological age of single neuron types in C. elegans, to probe their vulnerability or resilience to neurodegeneration,...

Here the link to our original open access article www.nature.com/articles/s43...

“One of the Greatest Challenges of Our Time”: Preventing Neurodegeneration In a new study, an aging clock has revealed neuron-specific aging, as well as potentially neuroprotective compounds.

“One of the Greatest Challenges of Our Time”: Preventing Neurodegeneration | Technology Networks

www.technologynetworks.com/neuroscience...

Huge congrats to Paulo da Silva, Baptiste Ropert, Matthias Rieckher, Corvin Rive!

🚀Our new preprint:🧠Neuronal 🧬DNA 🧬repair mediates systemic mitochondrial maintenance through acetylcholine signaling. Neuronal repair is sufficient for the overall health amid DNA damage! @cecad.bsky.social @unicologne.bsky.social @uniklinikkoeln.bsky.social
www.biorxiv.org/content/10.6...

Aging clocks delineate neuron types vulnerable or resilient to neurodegeneration and identify neuroprotective interventions - Nature Aging Gallrein et al. pair functional assays with clocks to compare chronological versus biological age of single neuron types in C. elegans, to probe their vulnerability or resilience to neurodegeneration,...

and here the link to our original open access article: www.nature.com/articles/s43...

How Aging clock reveals molecules that protect against neurodegeneration healthmedicinet.com/aging-clock-...

Read at least the abstract not only the title. Also, there are human brain aging and human drug screening data.

Aging clocks delineate neuron types vulnerable or resilient to neurodegeneration and identify neuroprotective interventions - Nature Aging Gallrein et al. pair functional assays with clocks to compare chronological versus biological age of single neuron types in C. elegans, to probe their vulnerability or resilience to neurodegeneration,...

Hier der link zu unserem open access Artikel: www.nature.com/articles/s43...

Aging clocks delineate neuron types vulnerable or resilient to neurodegeneration and identify neuroprotective interventions - Nature Aging Gallrein et al. pair functional assays with clocks to compare chronological versus biological age of single neuron types in C. elegans, to probe their vulnerability or resilience to neurodegeneration,...

Here the link to our open access original article: www.nature.com/articles/s43...

Aging clocks delineate neuron types vulnerable or resilient to neurodegeneration and identify neuroprotective interventions - Nature Aging Gallrein et al. pair functional assays with clocks to compare chronological versus biological age of single neuron types in C. elegans, to probe their vulnerability or resilience to neurodegeneration,...

Here the link to our original open access article: www.nature.com/articles/s43...

Do natural substances from blueberries and blue grapes protect nerve cells from aging? Using an aging clock, researchers from the University of Cologne have used the Caenorhabditis elegans model organism to demonstrate that nerve cells age differently. They identified both the cause ...

Do natural substances from blueberries and blue grapes protect nerve cells from aging?A www.bionity.com/en/news/1188...

A clock that measures the aging of nerve cells finds molecules that protect against age-related neurodegeneration Using an aging clock, researchers from the University of Cologne have used the Caenorhabditis elegans model organism to demonstrate that nerve cells age differently. They identified both the causes of...

A clock that measures the aging of nerve cells finds molecules that protect against age-related neurodegeneration | EurekAlert! www.eurekalert.org/news-release...

Aging clocks delineate neuron types vulnerable or resilient to neurodegeneration and identify neuroprotective interventions - Nature Aging Gallrein et al. pair functional assays with clocks to compare chronological versus biological age of single neuron types in C. elegans, to probe their vulnerability or resilience to neurodegeneration,...

🚨Thrilled to share this exciting new paper by our #FOR5762 project leader @bjornschumacher.bsky.social, published in #NatureAging!

The study uncovers neuron-specific aging patterns and points to potential neuroprotective interventions.

Congratulations! 🎉

www.nature.com/articles/s43...

To elucidate whether diff. neuron types differ in their biological aging process, researchers applied "BitAge" (binarized transcriptomic age clock) to 128 different neuron types in C. elegans & found that distinct neurons differ in their biological age
www.nature.com/articles/s43...

Aging clocks delineate neuron types vulnerable or resilient to neurodegeneration and identify neuroprotective interventions - Nature Aging Gallrein et al. pair functional assays with clocks to compare chronological versus biological age of single neuron types in C. elegans, to probe their vulnerability or resilience to neurodegeneration,...

Aging clocks delineate neuron types vulnerable or resilient to neurodegeneration and identify neuroprotective interventions
www.nature.com/articles/s43...

🧠 Nerve cells age differently
Researchers led by @bjornschumacher.bsky.social‬ @cecad.bsky.social have used C. elegans to prove for the first time that nerve cells age differently. Using an “aging clock” they were able to precisely determine the biological age of individual neurons👇 uni.koeln/FKJ35

Mikroskopbild eines Wurms mit transparentem Körper und grün fluoreszierenden Stellen entlang des Körpers. Mehrere Zellansammlungen sind sichtbar.

⏰🧠 Nervenzellen altern unterschiedlich
Forschende um @bjornschumacher.bsky.social @cecad.bsky.social haben in C. elegans erstmals nachgewiesen, dass Nervenzellen unterschiedlich altern. Mit einer „Alternsuhr“ konnten sie das biologische Alter einzelner Neuronen präzise bestimmen👇
uni.koeln/BWMMP

Eine Alternsuhr der Nervenzellen findet Moleküle, die vor altersbedingter Neurodegeneration schützen www.idw-online.de/-DTSBAA

Big thanks to @bjornschumacher.bsky.social for his guidance and all co-authors. This was a great team effort. Paper: www.nature.com/articles/s43...
(9/n)
#aging

🚨Publication Alert🚨
New work from our #CRC1678 members @bjornschumacher.bsky.social and @meyerdh.bsky.social reveals why some neurons age faster. Using neuron‑specific aging clocks, they identified vulnerable neurons and highlight syringic acid and vanoxerine as promising neuroprotective hits.🧬

Why do some neuron types degenerate early while others stay intact?

We used transcriptomic aging clocks for single-neuron-types in C. elegans and found neuron-specific biological age predicts vulnerability.
🧪

www.nature.com/articles/s43...

#Neurodegeneration 🧵👇 (1/n)

Aging clocks delineate neuron types vulnerable or resilient to neurodegeneration and identify neuroprotective interventions - Nature Aging Gallrein et al. pair functional assays with clocks to compare chronological versus biological age of single neuron types in C. elegans, to probe their vulnerability or resilience to neurodegeneration,...

🧠⏰our latest paper is out now: how each neuron ages differently allowed us to define in silico screens for new therapeutic molecules that could prevent neurodegeneration @cecad.bsky.social @unicologne.bsky.social @uniklinikkoeln.bsky.social @meyerdh.bsky.social www.nature.com/articles/s43...

Bild der Wissenschaft PODCAST – Folge 13: Ein Autopilot für Schiffe Cyril Alias erklärt, wie ein Autopilot Binnenschiffe durch Flussbiegungen und Stromschnellen navigieren könnte.

Curious about the role our genetic traits 🧬 and our lifestyle 🏄‍♀️ play in healthy ageing?
In the latest episode of the Bild der Wissenschaft podcast, our #CRC1678 project leader @bjornschumacher.bsky.social explains the science behind longevity!
🎙️Listen here: www.wissenschaft.de/gesundheit-m...

Können wir ewig leben, Björn Schumacher? Alternsforscher Björn Schumacher über ewiges Leben, unseriöse Versprechen und Faktoren, die das Leben wirklich verlängern können.

Die großen Fragen der Wissenschaft |
Können wir ewig leben? Im Gespräch geht es um die tiefgreifenden biologischen Mechanismen hinter dem Altern, ethische Grenzen bei der Lebensverlängerung und um sinnvolle Strategien, länger gesund zu leben detektor.fm/wissen/die-g...

Können wir ewig leben, Björn Schumacher? YouTube video by detektor.fm

Hier der Podcast: mein Gespräch über »Altersuhren«, Fadenwürmer, den Traum von der ewigen Jugend und die richtige Medizin youtube.com/watch?v=Q6ey...

Die großen Fragen der Wissenschaft: Können wir ewig leben, Björn Schumacher? Ein Gespräch mit dem Biologen Björn Schumacher über die Geheimnisse von Longevity – einem möglichst langen, gesunden Leben.

Heute im @spektrum.de der Wissenschaft: mein Gespräch über »Altersuhren«, Fadenwürmer, den Traum von der ewigen Jugend und die richtige Medizin www.spektrum.de/news/longevi...

Merry Christmas 🎄🎁 and happy new year 🎆🎈🎊 with all the best wishes for a great 2026