4/4 Having moved to #Seattle recently, I’m looking forward to #connect with people here.
Let’s #connect if you are into #protein sciences, #cancer research, #mentoring or just like to #chat about the #craft of doing #science
3/4 I’m passionate about #mentoring students, & improving access to #meaningful research #experiences. I’ve #guided high school & #undergraduate students on summer projects. Currently working on #grant writing for early career researchers.
2/4 My PhD focussed on #antimicrobial peptides designing, and then as a #postdoc, I studied PTMs in #cancer, especially how protein #glutamylation impacts #leukemia.
Hi @bsky.app, I’m Humaira, a molecular biologist and protein scientist passionate about decoding complex biological systems and translating that knowledge into therapeutic insights.
We discovered a new AML vulnerability:
TTLL4 glutamylates NPM1c and helps leukemia cells thrive.
Knock it down and cells differentiate and survival improves.
Collab between our lab and @Gritsman_lab—funded by NIH and DoD/CDMRP. Preprint: bit.ly/42oZl09 /1
TTLL4 glutamyltransferase is a therapeutic target for NPM1-mutated acute myeloid leukemia https://www.biorxiv.org/content/10.1101/2025.04.07.647605v1
TTLL4 glutamyltransferase is a therapeutic target for NPM1-mutated acute myeloid leukemia https://www.biorxiv.org/content/10.1101/2025.04.07.647605v1
