Vinod Mishra

Proximity-driven acceleration of challenging solid-phase peptide couplings | PNAS www.pnas.org/doi/10.1073/...

Magnetically sensitive proteins could lead to new imaging tools and remote-controlled drugs New study shows how engineered proteins can be tracked with an MRI-like approach

Magnetically sensitive proteins could lead to new imaging tools and remote-controlled drugs | Science | AAAS www.science.org/content/arti...

Good day!

Good day!

Honored to serve

Targeted protein degradation in the transmembrane and extracellular space Transmembrane and extracellular proteins play crucial roles in diverse cellular functions and communication, affecting the progression and treatment of various diseases by mediating vital cellular pro...

Targeted protein degradation in the transmembrane and extracellular space | Science www.science.org/doi/10.1126/...

Happy Sunday!

A beautiful Autumn day in Boaz, AL

Autumn in Boaz, AL

Alcohol use and risk of dementia in diverse populations: evidence from cohort, case–control and Mendelian randomisation approaches Objectives To investigate the relationship between alcohol consumption and dementia. Design Prospective cohort and case–control analyses combined with linear and non-linear Mendelian randomisation. ...

ebm.bmj.com/content/earl...

Night sky illuminated by bright moon!

Nature is beautiful!!

Digitalization paving the ways for sustainable chemistry: switching on more green lights The world is facing an interconnected crisis caused by a variety of factors including climate change, water scarcity, biodiversity loss, and chemical waste. One of most prominent factors is the exploi...

www.science.org/doi/10.1126/...

Could lithium stave off Alzheimer’s disease? The metal is depleted in brains of people with disease and can reverse memory symptoms in mice, new study shows

Could lithium stave off Alzheimer’s disease? | Science | AAAS www.science.org/content/arti...

Happy Friday!!

Happy Thursday!

Happy Sunday!

Happy July 4th!!

Happy Sunday!

Happy Saturday!

Beautiful lily!!

Orforglipron, an Oral Small-Molecule GLP-1 Receptor Agonist, in Early Type 2 Diabetes | NEJM Orforglipron is a small-molecule, nonpeptide glucagon-like peptide-1 (GLP-1) receptor agonist in clinical development for type 2 diabetes and weight management. Additional data on the efficacy and ...

Orforglipron, an Oral Small-Molecule GLP-1 Receptor Agonist, in Early Type 2 Diabetes | New England Journal of Medicine www.nejm.org/doi/full/10....

Proud of our daughter!!

Malnutrition in Older Adults | NEJM Malnutrition in older adults is common, underrecognized, and contributes to poor health and risk of death. Guidelines are available to facilitate prevention and treatment of malnutrition.

Malnutrition in Older Adults | New England Journal of Medicine www.nejm.org/doi/full/10....

The structure of human sweetness A single taste receptor initiates our reactions to both sugars and artificial sweeteners, triggering a signaling process that drives our intense attraction to sweet foods. Single-particle cryo-EM reveals the structure of the human sweet taste receptor, a heteromer composed of TAS1R2 + TAS1R3 GPCRs.

The structure of human sweetness: Cell www.cell.com/cell/fulltex...

Look beyond the longevity drips and supplements There is a path to living longer and healthier that doesn’t require reversing the aging process

Look beyond the longevity drips and supplements | Science www.science.org/doi/10.1126/...

Can gene-edited pigs solve the organ transplant shortage? With clinical trials imminent, hopes are rising high for the long-struggling field of xenotransplantation

Can gene-edited pigs solve the organ transplant shortage? | Science | AAAS www.science.org/content/arti...

Icosapent ethyl reduces arterial thrombosis by inhibition of cyclooxygenase-1–induced platelet reactivity Dose-dependent platelet inhibition by icosapent ethyl contributes to beneficial effects of polyunsaturated omega-3 fatty acids.

Icosapent ethyl reduces arterial thrombosis by inhibition of cyclooxygenase-1–induced platelet reactivity | Science Translational Medicine www.science.org/doi/10.1126/...

Technical recommendations for analyzing oxylipins by liquid chromatography–mass spectrometry Community-suggested best practices for the analysis of oxylipins are presented.

Technical recommendations for analyzing oxylipins by liquid chromatography–mass spectrometry | Science Signaling www.science.org/doi/10.1126/...

Hypoglycemia promotes inner blood-retinal barrier breakdown and retinal vascular leakage in diabetic mice Hypoglycemia promotes hypoxia-inducible factor-1 (HIF-1)– and HIF-2–dependent retinal vascular hyperpermeability in diabetic, but not control, mice.

Hypoglycemia promotes inner blood-retinal barrier breakdown and retinal vascular leakage in diabetic mice | Science Translational Medicine www.science.org/doi/10.1126/...