Amel Latifi

This…..

Structural basis of RNA-guided transcription by a dCas12f–σE–RNAP complex - Nature Cryogenic electron microscopy reveals how dCas12f with σE recruits RNAP to targeted DNA, initiating transcription at a fixed downstream distance, bypassing canonical −35 recognition and stabilizing th...

👀

www.nature.com/articles/s41...

🧵 Proud to present a tour de force by postdoc @gregbwhitfield.bsky.social solving the mystery of how bacterial Tad pili can extend and retract with a single motor ATPase. Great collaboration with Lynne Howell, @dr-lori-burrows.bsky.social, @ianyyen.bsky.social www.biorxiv.org/content/10.6...

PhD position with Natalia Tschowri (@unihannover.bsky.social) and Daniel Rozen (@unileiden.bsky.social @leidenscience.bsky.social) within @spp2389.bsky.social program

Regulation and Evolution of Bacterial Multicellularity

Application deadline until 15 March 2026

#PhDposition

Seasonal cycles select for self-sustained circadian oscillators Circadian clocks comprise self-sustained oscillators that anticipate time-of-day changes in the environment. Dani et al. report that seasonal changes in daylength can alone provide a strong selective ...

Seasonal cycles select for self-sustained circadian oscillators

@currentbiology.bsky.social by @danichitrang.bsky.social et al from Carl Johnson

www.cell.com/current-biol...

Please share!
My group at @zmbp-tuebingen.bsky.social is offering a post-doctoral position (4 years). We look for a structural biologist with experience in Cryo-EM/Cryo-ET to investigate the mechanisms of host invasion by pathogenic fungi. Deadline February 28th!
uni-tuebingen.de/universitaet...

AI can turbocharge scientists’ careers — but limit their scope Hear the biggest stories from the world of science | 14 January 2026

Happy Friday! For those of you who didn't see the excellent @nature.com paper showing that scientists who use AI tools produce more research but on a narrower range of topics, consider listening to the podcast: www.nature.com/articles/d41...

Magnifique, bravo!

Life’s evil twins, called mirror cells, could wipe us out if scientists don’t stop them Researchers are close to making “reversed” cells that may wipe us off the planet

What could mirror bacteria do in nature if created? A story of these prospects and a plan to prevent them.

Titles aside, I hope you'll read it (the tech is NOT close). Thanks to Tom Freeman for writing help & @jfischman.bsky.social for ace editing! www.scientificamerican.com/article/life...

Nous recrutons un Maître ou une Maîtresse de conférences en bactériologie moléculaire pour notre équipe MTSB au laboratoire MAP à Lyon, France.
Le poste combine recherche sur l'adaptation des bactéries phytopathogènes et enseignement en génétique microbienne.
Notre team : sites.google.com/view/mtsb

L’Agence nationale de la recherche (#ANR) est contrainte d’adapter temporairement ses activités dans le cadre des services votés. Le calendrier et la mise en œuvre des appels à projets, dans l’attente de l’adoption de la loi de finances pour 2026, sont précisés dans ce #communiqué ➡ bit.ly/3NyLwbI

Membrane editing with proximity labeling reveals regulators of lipid homeostasis - Nature Chemical Biology Coupling an optogenetic lipid-modifying enzyme with proximity labeling reveals protein networks and mechanisms regulating lipid homeostasis in the membranes of target organelles.

Thrilled to share our latest study, led by @reikatei.bsky.social, in @natchembio.nature.com! We began by asking a simple question—how do cells know if they have too much of a lipid in a particular membrane, and how do they respond to rectify this imbalance?
www.nature.com/articles/s41...
More info 👇

‘A serious problem’: peer reviews created using AI can avoid detection Tools fail to identify most AI-generated peer-review reports, say researchers, who warn that the issue is only getting worse.

Tools fail to identify most AI-generated peer-review reports, say researchers, who warn that the issue is only getting worse.

go.nature.com/44SntdQ

Hybridization breaks species barriers in long-term coevolution of a cyanobacterial population Analysis of hundreds of single-cell genomes from Yellowstone National Park shows bacterial species are less cohesive than previously thought.

Happy that our work on the evolution of Yellowstone cyanobacteria is now published in @elife.bsky.social: doi.org/10.7554/eLif...! Did a lot of work in revision—many thanks to the anonymous reviewers for great suggestions! Also see the eLife digest for a summary: elifesciences.org/digests/9084...

Amazing! Never saw that. Which Nostoc is it?

‘A serious problem’: peer reviews created using AI can avoid detection Tools fail to identify most AI-generated peer-review reports, say researchers, who warn that the issue is only getting worse.

Tools fail to identify most AI-generated peer-review reports, say researchers, who warn that the issue is only getting worse.

go.nature.com/3MTmdAR

Congrats

Unveiling the landscape of prokaryotic global regulators through deep protein language models | mSystems GRs are master transcriptional regulators critical for microbial adaptation, stress tolerance, and metabolic control, and they serve as valuable components for synthetic biology. However, a comprehens...

Unveiling the landscape of prokaryotic global regulators through deep protein language models

-in #mSystems

journals.asm.org/doi/10.1128/...

Merci Pierre

Co-option of an ancestral peptidase controls developmental patterning in multicellular cyanobacteria Developmental biology

How do simple cells make complex patterns? We discovered a key piece in cyanobacteria—an ancient enzyme repurposed to activate a pattern-forming signal. A conserved signaling strategy, showing how nature reuses tools to build multicellularity. www.cell.com/iscience/ful...

L’université Aix-Marseille commande une étude pour sonder les opinions politiques de ses étudiants Lancée en grande pompe par Aix-Marseille-Université, une campagne citoyenne pour pousser les étudiants à participer aux élections municipales divise la communauté éducative. Elle s’accompagne en effet d’une étude qui crispe, autant par sa méthodologie que par la sensibilité des données recueillies.

L’université Aix-Marseille commande une étude pour sonder les opinions politiques de ses étudiants

The future of AI Artificial intelligence is flying high. Nature asked leading innovators what they think will happen next.

If you're interested in AI, where it's heading, and the people behind the wheel, perhaps you'll give our new feature a look www.nature.com/immersive/d4...

« On va dans le mur » : des présidents d’université dénoncent un sous-financement chronique Conditions d’études dégradées, risque de fermeture de formation, manque de titulaires pour coordonner les parcours... Les universités manque

[ #VeilleESR #LRU ] « On va dans le mur » : des présidents d’université dénoncent un sous-financement chronique
par @cberthelemy.bsky.social

Très intéressant : CY Université est dans la même panade, malgré des indicateurs hors normes, montrant un grand respect des injonctions politiques.

Reviens😉

📢 Postdoc position: Cell Biology of Cyanobacteria

in my group, as part of the Excellence Cluster "Microbes for Climate" (M4C) in Marburg, Germany.

More information at shorturl.at/wNnDT (see Project 2)

🔗Apply at shorturl.at/VsEDl
📅Deadline: Nov 16, 2025

Please repost. #Postdoc

Climate Change in Antarctica Has Given Rise to Blooming Flowers This article delves into the changing climatic conditions in Antarctica that have given rise to these blooming flowers.

take note everybody

earth.org/antarcticas-...

bsky.app/profile/mfai...

Universities are embracing AI: will students get smarter or stop thinking? Millions of students arriving at campuses are now using artificial intelligence. Worries abound.

AI is being used more at universities, and, to some, it provides an opportunity to improve education and prepare students. But many education specialists are concerned it could impede learning. Nature reports on these worries. #Academicsky 🧪

Role of endopeptidases in lateral cell wall expansion in Escherichia coli Peptidoglycan, the major constituent of bacterial cell walls, is a giant macromolecule made of glycan strands cross-linked by short peptides, which pr…

Proud of our new study out in @cp-cellreports.bsky.social!
Using E. coli lacking all 8 endopeptidases, we provide direct evidence that peptidoglycan expansion during elongation requires ED-mediated insertion of one glycan strand at a time. This can be performed by MepS, MepM, MepH and PBP7 #microsky

Carbon metabolism shapes FtsZ levels and cell division in the cyanobacterium Anabaena PCC 7120 - Communications Biology This study provides evidence on how carbon metabolism regulates cell division among cyanobacteria. Manipulation of the TCA pathway directly impacts the FtsZ-dependent cell division by regulating its expression via the transcriptional factor NtcA.

Carbon metabolism shapes FtsZ levels and cell division in the cyanobacterium Anabaena PCC 7120 www.nature.com/articles/s42... #jcampubs