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@dalloliogm

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16.11.2024
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Latest posts by @dalloliogm

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The CAFA6 Challenge: predicting protein function from sequence My strategy involves a dual towers network approach

Here is my approach to the CAFA6 challenge: predicting protein function from sequence. It is based on converting everything into numbers, using ESM2 for protein sequences, and an LLM for Gene Ontology terms.

gmdbioinformatics.substack.com/p/my-strateg...

#CAFA6 #ESM2 #deepLearning #bioinformatics

14.12.2025 15:08 👍 1 🔁 0 💬 0 📌 0
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Arc Virtual Cell Challenge - part 4: Winners announced! Did Bio-Foundation models outperform traditional statistical approaches?

The winners of the Arc Virtual Cell Challenge have been announced!

Did a foundation model outperform regressions?
Did the leaderboard hacking matter in the end?

Here are my thoughts. gmdbioinformatics.substack.com/p/arc-virtua...

#ArcVirtualCellChallenge #VirtualCellChallenge

07.12.2025 15:51 👍 0 🔁 0 💬 0 📌 0

Proud to have contributed to this bioArXiv paper, presenting an Agentic System for Cell Type annotation in single-cell
open.substack.com/pub/gmdbioin...
🧬 🖥️
#singlecell #bioinformatics #ngs #cytetype

18.11.2025 11:35 👍 0 🔁 0 💬 0 📌 0
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New preprint: Multi-agent AI enables evidence-based cell annotation in single-cell transcriptomics The paper on CyteType is on bioArXiv!

Proud to have contributed to this bioArXiv paper, presenting an Agentic System for Cell Type annotation in single-cell
open.substack.com/pub/gmdbioin...

#singlecell #bioinformatics #ngs #cytetype

18.11.2025 11:33 👍 1 🔁 0 💬 0 📌 0
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Arc Virtual Cell Challenge part 3: how to train your own Virtual Cell Model Let's go through the example notebook on running STATE, Arc's Virtual Cell model.

My third article on the Arc Virtual Cell Challenge.

This time, we learn how to train our very first Virtual Cell Model.

gmdbioinformatics.substack.com/p/arc-virtua...

#ArcInstitute #VirtualCellChallenge #BiologicalModelling #FoundationModels #MachineLearning #ML

13.11.2025 11:11 👍 1 🔁 0 💬 0 📌 0

I'm participating in the Arc Virtual Cell Challenge. The objective is to predict the effect of gene perturbations in H1 cell lines.
Here is my diary - more posts to come soon!

gmdbioinformatics.substack.com/p/arc-virtua...

#bio #bioinformatics #arc #foundation_models

03.11.2025 14:07 👍 0 🔁 0 💬 0 📌 0
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Arc Virtual Cell Challenge: my diary A journey into bio-foundation models to predict perturbations in single-cell data

I'm participating in the Arc Virtual Cell Challenge. The objective is to predict the effect of gene perturbations in H1 cell lines.
Here is my diary - more posts to come soon!

gmdbioinformatics.substack.com/p/arc-virtua...

#foundation-models #arc @arcinstitute.org #ML

03.11.2025 14:06 👍 0 🔁 0 💬 0 📌 0
Times Table Animals - Welcome to Albert Animals!

My 8yo son and I developed a maths game called Times Tables Animals, featuring cute bunnies, maths, and volcanoes. Here is our story.
dalloliogm.github.io/Times-Table-...

@kilocode.ai @ttrockstars.bsky.social #llm #parents-ai

12.08.2025 10:23 👍 0 🔁 0 💬 0 📌 0
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Am I the slowest Kaggle user ever? I joined Kaggle 15 years ago - but I only started competing this year.

I joined Kaggle about 15 years ago. However, I never had time to complete the registration until earlier this year. Am I the person who has taken the most time to reach the Expert level on Kaggle? Let's look at the numbers :-)

gmdbioinformatics.substack.com/p/am-i-the-s...

06.06.2025 14:01 👍 1 🔁 0 💬 0 📌 0
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Medium: Read and write stories. On Medium, anyone can share insightful perspectives, useful knowledge, and life wisdom with the world.

In my opinion, MLflow is the missing piece for ensuring reproducibility of analysis in Bioinformatics. However, not many people in the field are familiar with it. Here I provide an example based on Differential Expression. medium.com/@dalloliogm/...
#Bioinformatics

#mlflow🧬🖥️

23.01.2025 12:51 👍 2 🔁 0 💬 0 📌 0
Foundation models for Biology: a short primer Foundation Models in Biology represent one of the most important advances in Bioinformatics in recent years. They are pretty different from…

Foundation Models for Biology are going to revolutionize Bioinformatics in 2025. I wrote a short article to explain what they are and how they can be used. #llm #bioinformatics

medium.com/@dalloliogm/...

17.01.2025 15:57 👍 1 🔁 0 💬 0 📌 0
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Home DeepLearning.AI | Andrew Ng | Join over 7 million people learning how to use and build AI through our online courses. Earn certifications, level up your skills, and stay ahead of the industry.

These two courses on DeepLearning.ai complement each other. The first one is about pre-training a LLM, and the second about fine-tuning them.

- learn.deeplearning.ai/courses/pret...

- learn.deeplearning.ai/courses/fine...

#llm-challenge #ai-challenge

30.12.2024 16:02 👍 1 🔁 0 💬 0 📌 0
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Giovanni Marco Dall'Olio, congratulations on completing Reasoning with o1! Giovanni Marco Dall'Olio, congratulations on completing Reasoning with o1!

o1 is the "Wise" model from OpenAI, the one that "thinks before it speaks" and thinks with its virtual right hemisphere.

This course summarizes the differences between o1 and other models, and how to optimize costs and times.

#ai-challenge #llm-challenge

learn.deeplearning.ai/accomplishme...

20.12.2024 15:48 👍 0 🔁 0 💬 0 📌 0
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Giovanni Marco Dall'Olio, congratulations on completing Understanding and Applying Text Embeddings! Giovanni Marco Dall'Olio, congratulations on completing Understanding and Applying Text Embeddings!

Just finished this course on Understanding and Applying Text Embedding.

Short and useful materials to understand how text can be embedded in a vector space, based on concept similarity, and used for training new models. #ai-challenge #llm-challenge

learn.deeplearning.ai/accomplishme...

20.12.2024 13:55 👍 0 🔁 0 💬 0 📌 0
LinkedIn This link will take you to a page that’s not on LinkedIn

I've just finished catching up on the 5-Day GenAI course from Kaggle and Google (www.kaggle.com/learn-guide/...)

I recommend this course to anyone wishing to learn more about LLMs. The explanations are clear, from the basics to the most technical parts. The Kaggle notebooks show concrete examples.

20.12.2024 12:10 👍 0 🔁 0 💬 0 📌 0
Whitepaper Companion Podcast - Foundational LLMs & Text Generation
Whitepaper Companion Podcast - Foundational LLMs & Text Generation YouTube video by Kaggle

2)
They also provide two podcasts where two speakers summarize the documents. The funny thing is, this podcast is completely generated by AI, and the two speakers are not real people!

www.youtube.com/watch?v=mQDl...
www.youtube.com/watch?v=F_hJ...

16.12.2024 14:44 👍 0 🔁 0 💬 0 📌 0
Foundational Large Language Models & Text Generation

1) They provide two white papers on Transformer Architecture and Prompt Engineering. A good resource for anyone wishing to learn more about these topics.
www.kaggle.com/whitepaper-f...
www.kaggle.com/whitepaper-p...

16.12.2024 14:44 👍 0 🔁 0 💬 1 📌 0

Ahah grazie :-)
Mi piacerebbe espandere la parte sugli agenti. Avevo solo 15 minuti per presentare, e non sono riuscito ad entrare in dettagli.

16.12.2024 14:42 👍 1 🔁 0 💬 0 📌 0
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5-Day Gen AI Intensive Course with Google Learn Guide

I'm catching up on the 5-day-GenAI course from Kaggle.
The first day introduces the Transformer architecture and the most important prompting techniques.

www.kaggle.com/learn-guide/...
#llm-challenge #ai-challenge

16.12.2024 14:41 👍 0 🔁 0 💬 1 📌 0
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Applicazioni di chatGPT e altri LLMs per la ricerca di farmaci Applicazioni di chatGPT e altri LLMs per la ricerca di farmaci - Download as a PDF or view online for free

LLMs are transforming drug discovery, but many outside the field don't know about it. Science communication is key to bridging this gap. 🧪🎄 Here is a short talk I gave at the 'Salute è Donna' conference in Lanciano, Italy. ✨ #AI #DrugDiscovery"

www.slideshare.net/slideshow/ap...

13.12.2024 08:58 👍 1 🔁 1 💬 1 📌 0
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How Diffusion Models Work - DeepLearning.AI Learn and build diffusion models from the ground up, understanding each step. Learn about diffusion models in use today and implement algorithms to speed up sampling.

This course gives a nice intro to Diffusion Models, including some examples of code for training a small diffusion model and generating some images in a notebook. learn.deeplearning.ai/courses/diff...

01.12.2024 14:14 👍 0 🔁 0 💬 0 📌 0
Learn Machine Learning Explainability Tutorials Extract human-understandable insights from any model.

Today I've completed this course from Kaggle, on Machine Learning explanability. It's a great course, including partial dependency plots, permutation importance, and SHAP values. #ai-challenge
llm-challenge www.kaggle.com/learn/machin...

28.11.2024 22:20 👍 0 🔁 0 💬 0 📌 0
Learn Intro to Deep Learning Tutorials Use TensorFlow and Keras to build and train neural networks for structured data.

Kaggle has a collection of excellent free courses on Data Science. Today I've completed the Intro to Deep Learning, which is a good refresher on the basis of TensorFlow and Keras to train neural networks. #ai-challenge #llm-challenge
www.kaggle.com/learn/intro-...

27.11.2024 22:24 👍 1 🔁 0 💬 0 📌 0

Most of these things can be achieved by copy&pasting from chatGPT, but in the course they use API calls to VertexAI, using text-bison-001, to better template it.

26.11.2024 14:22 👍 0 🔁 0 💬 0 📌 0

This course makes some good examples of pairing with a LLM:
- Improving existing code
- Simplify code
- Write Test Cases
- Make code more efficient
- Debug code
- Create documentation to reduce technical debt

26.11.2024 14:22 👍 0 🔁 0 💬 1 📌 0
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Giovanni Marco Dall'Olio, congratulations on completing Pair Programming with a Large Language Model! Giovanni Marco Dall'Olio, congratulations on completing Pair Programming with a Large Language Model!

Excellent course on Pair Programming with a Large Language Model!
I think this is the way of the future. Every programmer or data scientist should learn to use LLMs to improve their code.

learn.deeplearning.ai/accomplishme...

26.11.2024 14:22 👍 1 🔁 0 💬 2 📌 0

Key takeaways:
- they create a fantasy world using a hierarchical procedure, from world->kingdom->towns, using LLM queries and JSON to store data
- they use TogetherAI's APIs to serve models, and `gradio` as a textual UI
- content regulation and safety is done using LlamaGuard.

26.11.2024 13:53 👍 0 🔁 0 💬 0 📌 0
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Giovanni Marco Dall'Olio, congratulations on completing Building an AI-Powered Game! Giovanni Marco Dall'Olio, congratulations on completing Building an AI-Powered Game!

Another course on implementing applications using LLMs. In this case, they do something that any nerd should try at least once: creating a text-based role-play fantasy game.

learn.deeplearning.ai/accomplishme... #llm-challenge #ai-challenge

26.11.2024 13:52 👍 0 🔁 0 💬 1 📌 0

I've decided to start a personal challenge to upskill my LLM and AI/ML knowledge! Over the next month, until Christmas, I'll try to complete a course on LLM, transformers, and deep learning every day. Wish me luck! #llm-challenge #upskill #llm #ai-challenge

26.11.2024 13:49 👍 2 🔁 0 💬 0 📌 0