Jessica Pantaleo

Spatial and temporal dynamics of cancer-associated fibroblast niches in breast cancer - Breast Cancer Research Breast Cancer Research - Cancer-associated fibroblasts (CAFs) are the main constituents of the tumor microenvironment. Several studies have delineated CAF heterogeneity in different types of...

New paper out from the @kpietraslab.bsky.social lab.
I am happy to share that my first-author paper is now published. We map the spatial and temporal dynamics of cancer-associated fibroblasts in breast cancer using integrated spatial proteomics and transcriptomics.
link.springer.com/article/10.1...

Pericytes orchestrate a tumor-restraining microenvironment in glioblastoma - Nature Communications Improved understanding of the tumor ecosystem in glioblastoma is critical for developing new treatment strategies for the disease. Here, the authors identify pericytes as an active paracrine signaling...

New paper alert 🚨
We are delighted to present our latest paper in @natcomms.nature.com through fabulous work from co-first authors Sebastian Braun and Paulina Bolivar! Big thanks to all expert collaborators for taking this long journey with us!
Tweetorial in comments 🧵
www.nature.com/articles/s41...

Postdoc in Experimental Oncology - Lund (Stad), Skåne (SE) job with Lund University | 12838990 Lunds universitet, 009999 LUNDS UNIVERSITET, 310000 MED Lund University was founded in 1666 and is repeatedly ranked among the world’s top universi...

Join us for innovative explorations of the tumor microenvironment🔬 Learn cutting-edge technologies and grow in a dynamic environment💡 The postdoc will work alongside a doctoral student from @adaptmet.bsky.social, gaining access to collaborative partners across 🇪🇺.
Apply now👇
tinyurl.com/4mby45hf

Couldn’t have asked for a better PhD supervisor! Huge congratulations @kpietraslab.bsky.social 🏆

At the Brain Tumor Microenvironment Symposium @institutducerveau.bsky.social, Sebastian Braun presented our comprehensive study of pericytes in GBM 🤩. Pericytes act as guardians of the peri-vascular niche to prevent malignant cell invasion, read more at www.biorxiv.org/content/10.1...

Thrilled to see our work on CAFs and endocrine resistance in luminal breast cancer being recognized by @Oncogenejournal as one of the most downloaded papers in 2024 and part of their 'Best of 2024' collection

We have been waiting impatiently but can finally share our latest efforts in understanding the biology of the TGF-beta type I receptor ALK1 (gene name ACVRL1), see graphical abstract in post and the full article here: www.jci.org/articles/vie...
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We love to explore unexpected findings 🤔 Check out our two latest studies detailing the unexplored expression of ALK1 in immunosuppressive macrophages and the critical role of pericytes as a paracrine signaling hub in GBM.
www.biorxiv.org/content/10.1...
www.biorxiv.org/content/10.1...

We are live 🕺! Recruitment for the exciting MSCA doctoral network Adaptmet is now open. Join us and great collaborators across Europe to explore fundamental mechanisms of metastatic dissemination:
adaptmet.eu/recruitment/