Alex Koyfman's Avatar

Alex Koyfman

@emhighak

EM Physician+Educator+Pt Advocate // emdocs.net EIC & Co-founder // #EMRA45u45 // #GirlDad // #citizenofworld // #selfmade

93
Followers
8
Following
68
Posts
20.11.2024
Joined
Posts Following

Latest posts by Alex Koyfman @emhighak

Have successfully managed many of these pts. NIPPV is really 1a and NTG 1b. Have never really understood really high doses of NTG; have seen resultant hypotension and other extraneous cognitive load. Also data not robust for improving meaningful outcomes. #emimcc

21.02.2026 16:04 πŸ‘ 0 πŸ” 0 πŸ’¬ 2 πŸ“Œ 0
Preview
FOAM Cortex: A New Way to Access FOAMed Knowledge at the Point of Care - emDocs A new frontier for FOAMed.

Really excited to publish in @emdocs about FOAM Cortex (foamcortex.com). FOAMed resources like emDocs are amazingβ€”our goal is to help get that knowledge to the bedside faster. #FOAMed hashtag#MedEd.

www.emdocs.net/foam-cortex-...

@emhighak.bsky.social

07.01.2026 16:17 πŸ‘ 1 πŸ” 1 πŸ’¬ 0 πŸ“Œ 0

Contrast may cause anaphylacTOID reactions (not anaphyLAXIS)

(anaphylactoid rxns = angry mast cells spit out histamine; usually less severe than anaphylaxis)

Canadian guidelines: don't pre-treatment w/ steroid, give antihistamine

This makes physiological sense!

Thank you science! #1/3. #EMIMCC

18.11.2025 13:51 πŸ‘ 22 πŸ” 7 πŸ’¬ 1 πŸ“Œ 2

Don’t reflexively start B-blockers without looking at old data points and collecting new ones as subset of these pts have mod/severe decr in EF and will decomp. Esmolol over propranolol as you can stop drip. #emimcc

24.10.2025 14:49 πŸ‘ 3 πŸ” 0 πŸ’¬ 0 πŸ“Œ 0

Nuanced understanding of spectrum of any disease is so important. Not a one-size fits-all approach. Reflect on your current practice. Aggressively learn from cases with any angst/conflict. This is how you elevate care and your field. #emimcc

19.10.2025 16:34 πŸ‘ 4 πŸ” 0 πŸ’¬ 0 πŸ“Œ 0
Preview
a man wearing sunglasses and a green jacket is standing in a crowd and says `` do it '' . ALT: a man wearing sunglasses and a green jacket is standing in a crowd and says `` do it '' .

#4/4) ascenting cholangitis generally IS infected & OFTEN causes septic shock

be wary of patients w/ ascending cholangitis who seem OK (may crash)

source control is usually obtained via ERCP. this should be done regardless of how sick the patient is (nobody is β€œtoo sick” for source control).

19.10.2025 13:11 πŸ‘ 9 πŸ” 2 πŸ’¬ 1 πŸ“Œ 0
Preview
a group of surgeons are dancing in an operating room with the words happy surgery team great results ALT: a group of surgeons are dancing in an operating room with the words happy surgery team great results

#3/4) percutaneous drainage is over-utilized for acute calculous cholecystitis (2/2 pressure to do something now)

no high-quality data supporting drain insertion (RCTs failed to find benefit)

the ideal therapy for most patients is medical stabilization followed by early laproscopic cholecystectomy

19.10.2025 13:11 πŸ‘ 7 πŸ” 1 πŸ’¬ 2 πŸ“Œ 0
Preview
Sad Sad Bean GIF ALT: Sad Sad Bean GIF

normal mentation *doesn't* indicate adequate systemic perfusion

especially in cardiogenic shock, people can mentate well despite terrible CO & systemic perfusion

poor mentation is sometimes an early sign of *septic* shock, but often a very late indicator of other shock states #EMIMCC

08.10.2025 21:05 πŸ‘ 26 πŸ” 9 πŸ’¬ 3 πŸ“Œ 1

Crucial to learn from all fields of medicine in order to provide thoughtful, comprehensive care for the pts in front of us #emimcc

29.09.2025 00:28 πŸ‘ 1 πŸ” 0 πŸ’¬ 0 πŸ“Œ 0
Preview
Use of Phenobarbital for Treating Alcohol Withdrawal This quality improvement study evaluates the implementation, clinical outcomes, and safety of an electronic health record order set for intravenous weight-based phenobarbital loading for treating alco...

New study supporting phenobarb monotherapy for EtOH withdrawal😍

We’ve been seeing more pts with *combined* withdrawal lately (eg opioid + EtOH)

IMHO phenobarb is esp useful in complex withdrawal to tx EtOH w/d, avoid delirium, and avoid excessive GABA #EMIMCC

#1/2

jamanetwork.com/journals/jam...

25.09.2025 13:10 πŸ‘ 9 πŸ” 5 πŸ’¬ 2 πŸ“Œ 0

1 more point that will sharpen your clinical gestalt and decision making. Details matter, particularly in EM. #emimcc

22.09.2025 19:20 πŸ‘ 2 πŸ” 0 πŸ’¬ 1 πŸ“Œ 0
Preview
a girl with pigtails is wearing a hat and says be afraid . ALT: a girl with pigtails is wearing a hat and says be afraid .

gram negative rods *rarely* cause blood culture contamination

so a single blood culture growing gram-negative rods should generally be regarded as real & treated as such

(this is *unlike* GPCs, where one culture is often a false-positive due to skin organisms like coag neg staph) #EMIMCC

14.09.2025 12:02 πŸ‘ 27 πŸ” 2 πŸ’¬ 2 πŸ“Œ 0

Spectrum of disease w nuanced management. Hard to flesh out.

05.09.2025 22:06 πŸ‘ 1 πŸ” 0 πŸ’¬ 0 πŸ“Œ 0

Quite thoughtful on your end @pulmcrit.bsky.social. Something that would definitely benefit from standardization and benefit critically ill pts.

02.09.2025 16:21 πŸ‘ 1 πŸ” 0 πŸ’¬ 0 πŸ“Œ 0
Preview
Continuum of Preshock to Classic Cardiogenic Shock in the Critical Care Cardiology Trials Network Registry:

Answer: #2 normotensive cardiogenic shock

It’s sneaky, easy to miss but important to identify, diagnose cause, manage and admit to ICUβ€”not the floor tele unit

Occurs in about 12% of CS patients

Mortality 17%

www.jacc.org/doi/10.1016/...

10.08.2025 19:49 πŸ‘ 2 πŸ” 2 πŸ’¬ 0 πŸ“Œ 0

if you see a gram-negative that is resistant to ceftriaxone, this is a red flag for possible ESBL.

even if lab report states that the bacteria is "sensitive" to ceftazidime, cefepime, or piptazo, it may be advisable to avoid these.

06.08.2025 20:06 πŸ‘ 13 πŸ” 2 πŸ’¬ 1 πŸ“Œ 1

Incredible work. Thx for regularly elevating core clinical practice.

30.07.2025 22:27 πŸ‘ 1 πŸ” 0 πŸ’¬ 1 πŸ“Œ 0
Preview
Critical Care Drug Handbook AΒ  Β  BΒ  Β  CΒ  Β  DΒ  Β  E Β  FΒ  Β  GΒ  Β  HΒ  Β  Β IΒ  Β  Β J Β  KΒ  Β  LΒ  Β  MΒ  Β  NΒ  Β  O Β  PΒ  Β  QΒ  Β  RΒ  Β  SΒ  Β  T Β  UΒ  Β  VΒ  Β  WΒ  Β  XΒ  Β  Y Β  Z Acetaminophen Acetazolamide Acetylcysteine Acyclovir […]

I'm working on creating a critical care drug handbook (embedded into the IBCC, for free).

Working version here: emcrit.org/ibcc/drugs/

Are there other drugs that you'd like to see included?

(Apologies in advance for not including drugs that are exclusively available outside the USA) #EMIMCC

30.07.2025 14:34 πŸ‘ 68 πŸ” 18 πŸ’¬ 7 πŸ“Œ 0
The Cognitive Pause: Refractory Hypotension  #criticalcare #emergencymedicine
The Cognitive Pause: Refractory Hypotension #criticalcare #emergencymedicine YouTube video by EMSwami

The cognitive pause in refractory hypotension reminds us to stop, question our diagnosis + assumptions and consider alternate/additional pathologies
- Acidosis
- Hypothyroidism
- Iatrogenic anaphylaxis
- Hypocalcemia
- Occult hemorrhage
- RUSH Exam

youtube.com/shorts/bvWoL...
#EMIMCC

10.07.2025 22:50 πŸ‘ 1 πŸ” 1 πŸ’¬ 0 πŸ“Œ 0
Preview
two women are sitting next to each other and one is pointing at the camera ALT: two women are sitting next to each other and one is pointing at the camera

to recap: the dosing of antiepileptics for true, ongoing, life-threatening convulsive status epilepticus in an adult:

1st line:
πŸ‘ŠLorazepam 0.1 mg/kg IV (VA-COOP RCT)
πŸ‘ŠOr if no IV access: Midazolam 10 mg IM (RAMPART RCT)

2nd line:
πŸ‘ŠLevetiracetam 60 mg/kg up to a max dose of 4.5 grams (ESSETT RCT)

29.05.2025 22:06 πŸ‘ 15 πŸ” 2 πŸ’¬ 2 πŸ“Œ 1
Preview
Emergency Medicine Thinker Emergency Medicine Thinker: 9781009379915: Medicine & Health Science Books @ Amazon.com

Released today. Pls check out what makes EM unique and at the core of medicine: www.amazon.com/Emergency-Me.... Deep thx to remarkable authors/leaders in our field. #foamed #medsky #emimcc

27.03.2025 14:37 πŸ‘ 2 πŸ” 1 πŸ’¬ 0 πŸ“Œ 0

Agree with a lot of this. Thx for your high-level work and time.

17.03.2025 12:02 πŸ‘ 1 πŸ” 0 πŸ’¬ 0 πŸ“Œ 0
Preview
I have been doing this for 10Β years I have been doing this for 10 years now. I am not sure what the future holds. I am not sure what First10EM will look like in another 10 years. I am not sure these words will be published (although if you are reading it, I guess we have our answer). This is an exercise in self reflection. If it is posted publicly, it is either because I think a small number of long time readers might find it interesting, or because I hope to get some feedback on my musings.

I have been doing this for 10 years now - some reflections on #FOAMed and the future of First10EM

17.03.2025 10:10 πŸ‘ 9 πŸ” 2 πŸ’¬ 4 πŸ“Œ 1
Post image

PulmCrit blog: Michelin Chest Syndrome

A shallow pigtail chest tube straightens out & lacerates the lung…

Side-holes in the chest wall function as a conduit, pushing air into the subcutaneous tissue…

Massive subcutaneous emphysema occurs

blog: https://emcrit.org/pulmcrit/michelin-chest-syndrome/

15.03.2025 20:39 πŸ‘ 23 πŸ” 10 πŸ’¬ 0 πŸ“Œ 0
Preview
Emergency Medicine Thinker: Pearls for the Frontlines Emergency Medicine Thinker: Pearls for the Frontlines: 9781009379915: Medicine & Health Science Books @ Amazon.com

Please check this out: www.amazon.com/Emergency-Me.... Our field is so complex and crucial to success of medicine. #emimcc #medsky

08.03.2025 03:09 πŸ‘ 1 πŸ” 0 πŸ’¬ 0 πŸ“Œ 0
Preview
High risk and low incidence diseases: Pediatric intussusception Pediatric intussusception is a serious condition that carries with it a high risk of morbidity and mortality.This review highlights the pearls and pit…

Check out latest in EM decision making series: www.sciencedirect.com/science/arti.... Thx BLong, JEaster. #medsky #emimcc

22.02.2025 15:41 πŸ‘ 1 πŸ” 0 πŸ’¬ 0 πŸ“Œ 0

Very interested to hear what folks think of this for EM: www.acgme.org/globalassets... #medsky #emimcc

17.02.2025 00:38 πŸ‘ 1 πŸ” 0 πŸ’¬ 1 πŸ“Œ 0

version for new AF in ICU pt who needs urgent (not emergent) cardioversion:

1) start protocoled Mg gtt 1 g/hr
2) amio load & gtt
3) wait a few hrs
4) 1 mg ibutilide
5) if still in AF: DCCV

meds build up & work together

Mg/ibutilide/amio are synergistic

Mg prevents ibutilide-induced TdP #EMIMCC

11.02.2025 23:34 πŸ‘ 32 πŸ” 5 πŸ’¬ 8 πŸ“Œ 1

Fave afib management pearls? #medsky #emimcc @pulmcrit.bsky.social @emcases.bsky.social @petrosoniak.bsky.social @first10em.bsky.social @skylerlentz.bsky.social

31.01.2025 10:59 πŸ‘ 6 πŸ” 1 πŸ’¬ 3 πŸ“Œ 0