ShinyBlackShoe (Calum Polwart)

Trump says Starmer is 'no Winston Churchill' over Iran strikes Sir Keir Starmer had refused to grant the US permission to use the Diego Garcia military base.

www.bbc.co.uk/news/article...

Would take me seconds as PM to withdraw permission and tell them to get off my land.

I also doubt chemotherapy activity is massively because of delays. There will be some that are. Delays are mostly in diagnostics. You can flip back to NHS care when diagnosed.

The majority will be for treatment the NHS doesn't think is cost effective.

Cancer patients ditch NHS for private chemotherapy share.google/fKKhDJVQqyrf...

12% ⬆️ from 2021 to now. So if I did my maths right.. is less than a 2.9% annual increase in activity.

While the NHS thinks chemo activity increases 6-8% annually. In other words.. private sector under delivering

Feels nuts that this is even a standard!
Time critical...
24 hours...

Bank holiday confirmed in Scotland for Monday after World Cup opener The Tartan Army will be able to celebrate into the wee hours on Sunday, June 14, after a one-off bank holiday was granted by the King

Wow

news.stv.tv/scotland/ban...

Charlie must be desperate to be seen as a man of the people for some reason at the moment...

Last I heard they hadn't actually won the final.

Oh yes. I use the GG stuff normally. But always keen to try new things ;-)

New to #RPSLibrary:

Neonatal Formulary: Drug Use in Pregnancy and the First Year of Life – 9th ed. (2026)

Read it here: https://ow.ly/5Bmj50Y62pR under ‘Pediatrics'

There is clearly a need for more evidence of what to do at the 2y point onwards.

The early reports of pancreatitis all seemed early on in treatment. So the beyond 2y mark needs to capture info on ongoing risks (including financial toxicity).

The vast majority are using privately. I don't think private should be confused with using where there is no proven benefit. However, I'd gladly strike off* prescribers who are prescribing to those not within the evidence base.

*And for those who are not HCP arrest and prosecute

If you are one of those who develop complications that's bad. If you are one who develops pancreatitis without complications it's still far from ideal.

But obesity related health problems like stokes and heart attacks also have severe complications that are less than ideal...

The MHRA said 1.6m people?
And my reading was that they were saying it was the complications of pancreatitis that were extremely rare. In other words, you might sometimes get pancreatitis, but that it would only a proportion of cases which developed severe complications.

You close windows? I thought everyone left all windows and tabs open ... for eternity

Err...
Were you the kid at school who said it wasn't their fault they started a riot, because little Billy pushed you first...

Hobbycraft issues full recall of asbestos-tainted children’s play sand Craft retailer says there is ‘risk to health’ after some vials in Giant Box of Craft set contained fibrous tremolite asbestos Hobbycraft has issued a full recall of children’s coloured play sand after confirming some bottles contained asbestos, presenting “a risk to health”. The Guardian revealed at the weekend that the craft retailer had stopped selling the kit after being alerted to the risk but had stopped short of alerting customers who had already bought the item. Continue reading...

Hobbycraft issues full recall of asbestos-tainted children’s play sand

A male vegetarian Haggis sporting it's green tartan fur with classic three legs (two on the left showing he is male) smiles while eating grass. It is meeting a carnivorous lady haggis with it's two children. Wearing a red tartan fur these are obviously girl children and they have two legs on their right and one on the left. Picture courtesy of Gemini

Just remembering Jan 25th about 10 years back. Explaining to my colleague who last I heard was now CEO of a major Hospital Group in 🏴󠁧󠁢󠁥󠁮󠁧󠁿 about #Haggis Hunting.

For those who don't know the chap on the right is a vegetarian #Haggis & the lady on the left with her two kids are carnivore

#BurnsNight 🏴󠁧󠁢󠁳󠁣󠁴󠁿🥃

Immune Checkpoint Inhibitor–Associated Cardiovascular Toxic Effects This Special Communication outlines the International Cardio-Oncology Society position on immune checkpoint inhibitor–associated cardiovascular toxic effects.

jamanetwork.com/journals/jam...

Jenrick voted with the party.
Therefore Jenrick broke Britain.

Robert Jenrick joins Reform UK after being sacked by Tories The former minister says the Conservatives

www.bbc.co.uk/news/article...

Now I may be missing the point here... BUT...

If you were a Conservative MP who had a vote in parliament and you now say Conservatives ruined Britain... Why does changing which 🏵️ you are wearing make you electable at the next election?

Jenrick was a Conservative.

Package inserts...

Are you using it orally? Or do you have an IV version?

IIRC the time to absorption is massive. If you aren't dosing it several hours before, you are not dosing it!

So are you using some other random H2, in the absence of ranitidine?

We have basically not used H2 for premed since ranitidine.

H2-antagonists in paclitaxel premedication: systematic review and meta-analysis This systematic review and meta-analysis aimed to investigate the necessity of histamine-2 antagonists (H2As) in paclitaxel premedication protocols, particularly in preventing hypersensitivity reactio...

spcare.bmj.com/content/earl...

Further reinforcement that H2 antagonists are not necessary with Paclitaxel.

Erm. It has chocolate in it...

...the real question is how have I got 4 days behind schedule!!

Big thoughts today...

I'm behind on opening my advent calendar...

...does that make Christmas come later?

True. Mine probably wasn't a Sunday. You are right. Never trust a Sunday train

I've been to an event there. It was remarkably unexciting to go home from! I was going to a London Hotel. It's not a huge station. The walk down to the station seems to act as a filter. And there's a fair amount of bussing and ubering.

Compared to events elsewhere in the country.. ..it's OK!

All patients should undergo pharmacogenetic testing before being prescribed clopidogrel A UK-first guideline has recommended that all patients should have pharmacogenetic testing to identify clinically relevant CYP2C19 genetic variants, regardless of indication. The clinical guideline,…

A UK-first guideline has recommended that all patients should have pharmacogenetic testing to identify clinically relevant CYP2C19 genetic variants, regardless of indication

#ukpharmacy #pharmacogenomics #bloodclots

But you can wash your hands after touching the tongs, you can't wash the pastry or whatever it is.

It may require observation. I suspect there are people who consider hygiene less than you...

If people don't put the food item back...

...say "Jury's can't handle the complexity" and before you know it, there is no jury ever