Congratulations to Sarah on passing her qualifying exam! A new PhD candidate is minted!
09.02.2026 23:44
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Congratulations to Sarah on passing her qualifying exam! A new PhD candidate is minted!
Representative coronal sections at the level of the posterior anterior commissure (pAC; dashed outline) showing lateral ventricle morphology in P7.5 brains following P0.5 ICV injections.
Dose is key🗝️. Higher doses of AAV (1uL of 4 x 10^12 GC/mL) consistently induced ventriculomegaly and permissive tropism in neonates, while moderate doses (1uL of 1 x 10^12 GC/mL) did not. Study led by Luke Liu, with true collaborative effort with Ania Noguera, Ryan Humphries, and Blake Zhou.
Representative 3D reconstructions of brain ventricles from control and high-dose AAV2/5-injected pups at 2, 5, and 7 days post-injection (P2.5, P5.5, P7.5). Quantification of total ventricular volume across time points. (n = 3 per condition).
📃Preprint alert @biorxivpreprint.bsky.social. Does your 2026 involve ICV injection of AAVs 🧠? If so, this study led by Luke is for you. "Adeno-associated viruses (AAVs) induce dose-dependent neonatal ventriculomegaly following intracerebroventricular administration" www.biorxiv.org/content/10.6...
Adeno-associated viruses (AAVs) induce dose-dependent neonatal ventriculomegaly following intracerebroventricular administration https://www.biorxiv.org/content/10.64898/2025.12.30.697113v1
Adeno-associated viruses (AAVs) induce dose-dependent neonatal ventriculomegaly following intracerebroventricular administration https://www.biorxiv.org/content/10.64898/2025.12.30.697113v1
Fame lab!
Such a joy to celebrate with this group! Happy holidays from our lab to yours! 🧠☃️
All aboard the Lab Train!!🚂
Congratulations to Sane Lann Phyo on a fantastic end-of internship presentation with @ccopstanford and the super mentorship from Blake Zhou. We have been so lucky to be part of Sane's research journey 🧠 @stanfordnsurg.bsky.social !
Blake Zhou Sunday, 11/16, 8am-12pm. Presentation Number: PSTR053.24/ A22 Location/Room: A22 SDCC Halls B-H Arjun Rajan Sunday, 11/16, 1pm-5pm. Presentation Number: PSTR102.04/A40 Location/Room: A40 SDCC Halls B-H Luke Liu + Ryann Fame Tuesday 11/18, 1pm-3:45pm. Session Number: Nanosymposium NANO040 Session Title: Choroid Plexus and CSF Biology Location/Room: SDCC Rm 24A Nano040.04; Nano040
Will you be at @sfn.org #SfN25? Yes? Us too! Come see the Fame lab!
The Fame Lab is 3 years old this week! Time flies with this fantastic group of scientists!
Thrilled to receive support from the Wu Tsai Neurosciences Institute for new investigations with a fantastic collaborator @heilshornlab.bsky.social . Congratulations to all of the teams!🧠
neuroscience.stanford.edu/news/pain-al...
Third Annual Dish Dish Dish to enjoy each other's company and celebrate a love of science! 📡 🗣️ 🍽️
Today, we celebrate Ania Noguera's time in the lab. On her last day with us, we are so excited about her transition to @ucberkeleyofficial.bsky.social - but will miss her expertise here! 🧠
Last day in the lab for Rachel's @devbiostanford.bsky.social rotation and Ran's @meharryresearch.bsky.social REACH program. Went to lunch with the magnificent mentor Arjun to celebrate their achievements! Time files when you're working with great people!
Every year SfN brings together thousands of researchers at every career stage to discover new ideas, share their research, and experience the best the field has to offer.
Register now to join the community at #SfN25 in San Diego!
🔗 vist.ly/3ys5s
#neuroskyence #neurosky
Stepping out of the lab to enjoy some artistic pursuits!
Molecular Hallmarks of Hydrocephalus @ScienceTranslational Medicine is out today. Grateful to work under leadership of Andy Hale, Ryann Fame, & Kris Kahle with other top-notch collaborators including @labfame.bsky.social members Arjun Rajan and Blake Zhou! www.science.org/doi/10.1126/...
Many thanks to the editors of @natureportfolio.nature.com
Biological Timing and Sleep for treating this important topic and for the collegial and scholarly reviewers who reviewed this article!
A The major components of the CSF system include CSF, choroid plexus, and circumventricular organs. These systems change their properties across time of day, including those listed below each component. B Multiple inputs affect the CSF system across time of day.
How does the brain 🧠 change around the clock 🕰️? Can this inform treatments?
Learn more in a new review from the lab 'Harnessing the #circadian nature of the choroid plexus and cerebrospinal fluid' ➡️ npj Biological Timing & Sleep | #Nature @natureportfolio.nature.com
www.nature.com/articles/s44...
She was also awarded the prestigious Cooke Fellowship to her upcoming transfer to a 4-year University! www.jkcf.org/our-stories/...
Congratulations to Aye Chan Moe (Rue) on her end-of internship presentation with @ccopstanford. She's now getting ready to spend the summer doing research @MIT with @MSRP. We have been so lucky to be part of her research journey 🧠@stanfordnsurg.bsky.social !
This is a trainee seminar series and your participation is very important and much appreciated. Join us next week. Here is the free registration link:
streamyard.com/watch/wHnr7P...
Just us making art out of trying to figure out the white balance on a demo scope! #choroidplexus
🧠Faculty Job alert for #devbiol researchers in sensory systems! The Department of Otolaryngology at Stanford School of Medicine is hiring a new Developmental Biology Research Faculty Member. Come be our neighbor! Find out more: facultypositions.stanford.edu/en-us/job/49...
#Careers #Hiring #Faculty
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Something to smile about! Pi-day Friday!
Congratulations to Stanford Medicine neuro-oncologist Michelle Monje. Learn more about Monje's groundbreaking work: stan.md/4gZHRh7
Sophia and Ryann toast to Sophia's successful Qualifying Exam result in front of the Lokey Building at Stanford.
Congratulations to Sophia Mirda on an unambiguous pass for her Qualifying Exam in @devbiostanford.bsky.social! A new PhD Candidate is minted!🥂
Juliet Knowles' research has recently shown that the brain can use adaptive myelination to perfect “skills” that are actually pathological, such as having seizures. stanmed.stanford.edu/epileptic-se...
Impressive work studying the GABA switch in pigs and its association with TBI. 🐖🧠 Congratulations Alex Hochstetler!
