Zam Kassiri's Avatar

Zam Kassiri

@zamkassiri

Professor, Cardiac and vascular matrix remodeling. Deputy Editor AJPHeart. U of Alberta, Dept Physiology #ualberta www.kassirilab.com

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30.11.2024
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Latest posts by Zam Kassiri @zamkassiri

Screenshot of an article from the Australian Financial Review. The headline reads: IFM Investors wants to pump $10b into Canada.

Screenshot of an article from the Australian Financial Review. The headline reads: IFM Investors wants to pump $10b into Canada.

These investments will help create thousands of high-paying careers for Canadian workers and unlock important new opportunities for our businesses.

05.03.2026 22:15 πŸ‘ 627 πŸ” 130 πŸ’¬ 61 πŸ“Œ 16
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Two nations under different skies, with the same values and ambitions. The Land Down Under and the Truth North Strong and Free. πŸ‡¦πŸ‡ΊπŸ‡¨πŸ‡¦

05.03.2026 02:50 πŸ‘ 1607 πŸ” 273 πŸ’¬ 109 πŸ“Œ 26
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While we sit around to find out how bad exactly it all is, a bit of cheer: the best baguette of Paris competition was won by a Sri Lankan who appears to have started as a dish washer in restaurants and eventually trained as a Boulanger.

www.paris.fr/pages/la-mei...

28.02.2026 21:49 πŸ‘ 6332 πŸ” 934 πŸ’¬ 79 πŸ“Œ 59
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ADAM17 Sheddase #Atherosclerosis

Myh11+ Smooth Muscle Cell Adam17 KO🐭+HFD➑️
⏫Lesion burden
⏫Aortic valve dysfunction
⏫Foamy SMCs

Adam17-deficient aortic SMCs➑️
⏫Lipid uptake (CD36 SRA1 LAL)
⏬Lipid efflux (ABCA1)

@zamkassiri.bsky.social #Atherosclerosis 2025
www.sciencedirect.com/science/arti...

18.01.2026 13:44 πŸ‘ 4 πŸ” 2 πŸ’¬ 0 πŸ“Œ 0
Li et al. Cardiovascular Research 2026

doi: 10.1093/cvr/cvaf256

Li et al. Cardiovascular Research 2026 doi: 10.1093/cvr/cvaf256

suppressing fibroblast activity too early after MI -> not good; suppressing myoFB activity after the early pos-MI phase -> Great! And the benefits lasted for 4 weeks (in mice)!
Extreme hard work by PhD student, Yingxi Li and great collab with Engineering (L Westover).CVR2026 doi: 10.1093/cvr/cvaf256

15.01.2026 18:03 πŸ‘ 3 πŸ” 2 πŸ’¬ 1 πŸ“Œ 0
Meganathan et al. Atherosclerosis. Dec 2025

Meganathan et al. Atherosclerosis. Dec 2025

Finally in Publication: knockdown of ADAM17 in smooth muscle cells markedly worsened atherosclerosis (in LDLR-KO mice) even though plasma hyperlipidemia remained unchanged. Arterial cells are critical players in atherosclerosis development. (Atherosclerosis. 2025 doi: 10.1016/j.atherosclerosis)

15.01.2026 17:45 πŸ‘ 2 πŸ” 2 πŸ’¬ 1 πŸ“Œ 0
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it appears your manuscript "in preparation" was not published in 2025 after all, mr. bond

22.12.2025 12:45 πŸ‘ 145 πŸ” 19 πŸ’¬ 2 πŸ“Œ 1
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While in Chicago, I took a tour around the Obama Presidential Center. I can’t wait for you all to visit in June 2026. Here’s a sneak peek:

18.12.2025 16:50 πŸ‘ 14069 πŸ” 2978 πŸ’¬ 719 πŸ“Œ 278
Black-and-white photograph of Wilma Rudolph crossing the finish line to win the women’s 4Γ—100 m relay gold for the United States at the 1960 Rome Olympics on September 8, 1960. The 20-year-old Tennessee State Tigerbelle leans forward in full stride, baton raised triumphantly, as she becomes the first American woman to win three track-and-field gold medals in a single Games. The packed Stadio Olimpico blurs behind her in this iconic moment of speed and history.

Black-and-white photograph of Wilma Rudolph crossing the finish line to win the women’s 4Γ—100 m relay gold for the United States at the 1960 Rome Olympics on September 8, 1960. The 20-year-old Tennessee State Tigerbelle leans forward in full stride, baton raised triumphantly, as she becomes the first American woman to win three track-and-field gold medals in a single Games. The packed Stadio Olimpico blurs behind her in this iconic moment of speed and history.

Smiling portrait of Wilma Rudolph proudly holding up 2 of her 3 gold medals with the 3rd medal worn like a necklace. All 3 from the 1960 Rome Olympicsβ€”won in the 100 m, 200 m, and 4Γ—100 m relay.

Smiling portrait of Wilma Rudolph proudly holding up 2 of her 3 gold medals with the 3rd medal worn like a necklace. All 3 from the 1960 Rome Olympicsβ€”won in the 100 m, 200 m, and 4Γ—100 m relay.

#OTD in 1961, AP names Wilma Rudolph Female Athlete of the Year for the 2nd consecutive year

Rudolph overcame childhood polio to become the fastest woman runner in the world; first American woman to win 3 track/field gold medals in a single Olympiad, Rome 1960.

#WomenInSport #champion #inspiration

17.12.2025 18:06 πŸ‘ 1578 πŸ” 323 πŸ’¬ 23 πŸ“Œ 18
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it's more of a comment than a ques

12.12.2025 06:43 πŸ‘ 246 πŸ” 35 πŸ’¬ 2 πŸ“Œ 2
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Adding one original sentence to the recommendation letter that Chatgpt composed

06.12.2025 11:51 πŸ‘ 111 πŸ” 9 πŸ’¬ 2 πŸ“Œ 0
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I’m happy that my PhD time will count at some point in my life. Or death.

26.11.2025 17:08 πŸ‘ 29 πŸ” 7 πŸ’¬ 2 πŸ“Œ 1
The brand new website of the Bischoff lab

The brand new website of the Bischoff lab

... together with my SciArt Gallery :)

... together with my SciArt Gallery :)

So excited to share this as a new junior PI:

My brand-new lab website! πŸŽ‰πŸͺ°πŸŒ€
www.bischofflab.com

Please pass it on to young, motivated researchers looking for PhD positions 😊

And for the #FluorescenceFriday community: don’t miss the SciArt Gallery!

#CellBio #DevBio #PhDjob #PhDposition #Science

27.11.2025 08:26 πŸ‘ 192 πŸ” 58 πŸ’¬ 12 πŸ“Œ 4
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I swore an oath to the Constitution in 1986. I've upheld it through 25 years of service and every day since I retired.

If Trump's trying to intimidate me, it won’t work. I’ve given too much to our country to be silenced by bullies who care more about power than the Constitution.

24.11.2025 20:27 πŸ‘ 11776 πŸ” 2932 πŸ’¬ 526 πŸ“Œ 204
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After you help your boss convert a doc to PDF

22.11.2025 16:55 πŸ‘ 11515 πŸ” 1411 πŸ’¬ 131 πŸ“Œ 59
Generative A.I., the thing that drives our whole economy right now, is a perfect metaphor for the abject failure of imagination on the part of the powerful. Generative A.I. has no imagination and offers no new insights. It's a mere predictive engine that uses statistics to find the most likely next thing. What's the next word in a sequence, the next pixel in a picture? This is the opposite of imagination, which is so often about finding the least likely thing, the startling incongruity. I worry that so many of us are outsourcing our imaginations and our whole creative selves to these stochastic parrots.

Generative A.I., the thing that drives our whole economy right now, is a perfect metaphor for the abject failure of imagination on the part of the powerful. Generative A.I. has no imagination and offers no new insights. It's a mere predictive engine that uses statistics to find the most likely next thing. What's the next word in a sequence, the next pixel in a picture? This is the opposite of imagination, which is so often about finding the least likely thing, the startling incongruity. I worry that so many of us are outsourcing our imaginations and our whole creative selves to these stochastic parrots.

Excellent speech by @charliejane.bsky.social about imagination in service to society. Great stuff.

buttondown.com/charliejane/...

22.11.2025 18:31 πŸ‘ 205 πŸ” 90 πŸ’¬ 5 πŸ“Œ 4

Very proud to share our lab’s recently published work in AJP-Heart

Early in my NIH K08 on #EndMT, we found an interesting signal in COL8A1 in athero, w/ biphasic response to TNF

πŸ™πŸ» to ⭐️ postdoc Qian Li for leading us here (& @haoyin.bsky.social for summary!)

journals.physiology.org/doi/full/10....

21.11.2025 13:53 πŸ‘ 5 πŸ” 3 πŸ’¬ 1 πŸ“Œ 0
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James Watson, dead at 97, was a scientific legend and a pariah among his peers James Watson, the co-discoverer of the structure of DNA who died Thursday at 97, was a scientific legend and a pariah among his peers.

If you read only one obit of James Watson, read this one

www.statnews.com/2025/11/07/j...

(From the late Sharon Begley, for @statnews.com )

09.11.2025 11:56 πŸ‘ 20 πŸ” 7 πŸ’¬ 3 πŸ“Œ 1
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πŸŽ₯ Hear from Roxana Mehran as she breaks down the key findings and clinical implications of the DECAF Trial – straight from #AHA25

#ESCTVOntheRoad

09.11.2025 15:53 πŸ‘ 3 πŸ” 2 πŸ’¬ 1 πŸ“Œ 0
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Calling all coffee drinkers! Dr. Khan has good news from the DECAF trial presented at #AHA25. β˜•β˜•β˜•

09.11.2025 16:21 πŸ‘ 7 πŸ” 2 πŸ’¬ 1 πŸ“Œ 0
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ANGPTL3, presented at #AHA25 showed gene editing demonstrates few adverse events.

More from Dr. HarringtonπŸ‘‡πŸ‘‡

09.11.2025 16:24 πŸ‘ 5 πŸ” 1 πŸ’¬ 0 πŸ“Œ 0
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Engage with the editors of American Heart Association Journals every day at #AHA25! These interactive sessions will provide invaluable insights into the latest trends, future directions, and the editorial process.

Go to https://www.ahajournals.org/AHASessions and mark your calendars today!

08.11.2025 17:19 πŸ‘ 0 πŸ” 3 πŸ’¬ 0 πŸ“Œ 0
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#AHA25: VITAL-AF trial: Stressor-associated atrial fibrillation (AF) carries similar risks of stroke, bleeding, and death as primary AF ; yet patients are less likely to receive oral anticoagulation, even when stroke risk is high. https://ahajrnls.org/4nJRQJQ

08.11.2025 17:36 πŸ‘ 3 πŸ” 2 πŸ’¬ 0 πŸ“Œ 0
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Protective role of soluble CD52 in obesity-associated steatotic liver disease and glucose dysregulation in mice. Soluble CD52 (sCD52) derived from activated CD4+ T cells regulates T cell immunity under autoimmune conditions; however, its role in obesity-associate…

Here the authors propose T cell-derived sCD52 as a therapeutic target to mitigate #obesity-associated #MASLD and glucose intolerance www.sciencedirect.com/science/arti...

05.11.2025 12:04 πŸ‘ 4 πŸ” 2 πŸ’¬ 0 πŸ“Œ 0
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CDC Figures It Easier To Start Tracking People Without Measles ATLANTAβ€”As the agency struggles to manage a measles caseload that has erupted to its largest size in decades, the Centers for Disease Control and Prevention stated Monday that at this point, it would ...

CDC Figures It Easier To Start Tracking People Without Measles

04.11.2025 21:00 πŸ‘ 1741 πŸ” 271 πŸ’¬ 16 πŸ“Œ 20
Robert Munsch donates his archives to Guelph Public Library Robert Munsch donates his archives to Guelph Public Library

Robert Munsch has donated his personal archives of stories and materials to the Guelph Public Library.

This is wonderful for such a valuable archive to be given to a public municipal library.

www.guelphpl.ca/Modules/News...

04.11.2025 23:31 πŸ‘ 217 πŸ” 38 πŸ’¬ 3 πŸ“Œ 4

https://www.theglobeandmail.com/gift/aaa9fec50b2b595cc0291494fc97e4bd10e7d6945d5c457e0bfa75d42846a705/ETWOFKPB7NGPPBFFEGKRNIBLAU

04.11.2025 11:20 πŸ‘ 3 πŸ” 3 πŸ’¬ 0 πŸ“Œ 0
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How much are MPs entitled to know about research grants? Not as much as you think. - Globe and Mail

04.11.2025 11:19 πŸ‘ 4 πŸ” 5 πŸ’¬ 1 πŸ“Œ 0
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02.11.2025 20:55 πŸ‘ 1 πŸ” 1 πŸ’¬ 0 πŸ“Œ 0