Jazlyn Mooney

Introgression and parental conflict shape repeated occurrences of postzygotic isolation in Mimulus Postzygotic reproductive isolation is often thought to accumulate as a byproduct of neutral divergence. Yet it frequently evolves rapidly, in line wit…

I am SO THRILLED to share our first fully-lab lab paper!!!!!! Led by @hybridzones.bsky.social & @hagarsoliman.bsky.social, w/ a major assist from @pfschwarz.bsky.social!!!!!!!!!!!!! Read more below, if you're curious (you should be- it's AWESOME!!!!!!!)

link: www.sciencedirect.com/science/arti...

📣 SING USA 2026 applications are open!

The Summer Internship for Indigenous Peoples in Genomics (SING) workshop will be July 19–24, 2026 at UW–Madison.

⏰ Apply by March 13 (midnight Hawaiʻi time)

Learn more & apply: sing.nativebio.net

Please share with Indigenous students!

#Indigenous #Genomics

The @scilifelab.se Ancient DNA Unit is recruiting a (permanent) Research Engineer for planning user projects and generating #aDNA 🧬 data:

Application deadline: March 25th 🧪🏺

www.uu.se/en/about-uu/...

Have you ever wondered how many archaic populations contributed DNA to modern humans? We know about Neanderthals and Denisovans, but the fossil and genetic evidence suggests a much more complex history!

www.biorxiv.org/content/10.6...

Based on a 2025 study by the great @jazlynmooney.bsky.social & colleagues

What the ‘Birthday Paradox’ Can Teach Us About Black History Opinion | Statistics can help fill in historical gaps, revealing surprising and empowering things about the past and present.

New for @undark.org

On: "The Birthday Paradox," the transatlantic slave trade, ancestral bonds, and the hidden power of statistics.

"Family is family, whatever our genetic relationship. Impressively, the birthday paradox study captures this possibility."

undark.org/2026/02/27/o...

Stanford researchers help trace ancestry for African Americans A group of Stanford researchers is offering a mathematical model to help link family connections up to 410 years ago.

Excited that our work was featured on the local (Bay Area) news for their Black History month series. Interview with Noah and clips from my interview with @dornsife.usc.edu and CGSI talk in the article below

www.nbcbayarea.com/discover-bla...

Promises to be poppin (🍿)

BUT SRSLY PLEASE REGISTER, WE ARE SO EXCITED!!!!!!!!!!!!

The PopGen Vienna Seminar series schedule is ready for the next term (March-June). It's jam-packed with fantastic speakers in #evolution, #genetics, #genomics, #popgen, and more! Details and streaming link signup can be found on our website popgen-vienna.at/news/seminars/

New paper! From Sam Snodgrass and @genomeofforrest.bsky.social, w/ @druncie.bsky.social, @gcbias.bsky.social, and a collaboration with Andres Moreno and @santiagogmm.bsky.social. Can we quantify the impact of humans on maize dispersal?

Plant yourself in a comfy chair and lend me your ear:

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Marie Taylor - Wikipedia

In celebration of #BlackHistoryMonth let’s learn more about Marie Taylor, a plant biologist and chair of Howard University’s Botany Department. Love her focus on photomorphogensis and using light microscopy on living plants! 🌱 en.wikipedia.org/wiki/Marie_T...

Check out this preprint. Tianlin Duan led this project during her postdoc with me and Mike Whitlock.

It’s got a lot of stuff in it for those who are interested in the genomics of adaptation

Beyond Controversy? The Promotion and Early Critical Reception of Sociobiology: The New Synthesis, Fifty Years Later - Journal of the History of Biology Journal of the History of Biology -

"Instead of unifying different strands of animal behavior research, Sociobiology amounted to an individualistic effort aiming to supersede ongoing developments in the field. Wilson neither provided the theoretical cohesion nor inspired the social unity necessary for the foundation of a discipline"

Cool new work from Sophie Buysee w/ @jeffreykconner.bsky.social on how different Arabidopsis thaliana populations respond to drought.

Differentiation for drought strategy but conserved plasticity to heat and drought in locally adapted populations of Arabidopsis thaliana https://www.biorxiv.org/content/10.64898/2026.01.07.698234v1

What We Inherit Debating the use of genomic tools and their societal impact

Less than a month before my debut book "What We Inherit" gets released! You can place pre-orders now: press.princeton.edu/books/hardco...

Lucky to have gotten to collaborate (and argue) with Sam Trejo for the last 5+ years on this.

How Genotype-by-Environment Interactions Can Maintain Variation in Mutualisms | The American Naturalist Abstract Coevolution requires reciprocal genotype-by-genotype (G × G) interactions for fitness, which occur when the fitness of a genotype in one species depends on the genotype it interacts with in a...

Carlson et al. build a mathematical model considering how genotype-by-environment interactions can maintain variation and parametrize their model to test its applicability to real mutualisms.

Read now ahead of print!
www.journals.uchicago.edu/doi/10.1086/...

Coloured illustration of a Rosa persica (Persian rose). The slightly yellowed page shows stem, leaves, two yellow flowers and one in the process of flowering. Two yellow petals are shown dropping at the bottom.

🌺If you're free on 15th January and would like to find out more about our Persian collections, why not sign up for one of our art workshops? More info in the booking links below 👇#KewLA

Morning slot: https://ow.ly/x0cl50XMcGy
Afternoon slot: https://ow.ly/IvwE50XMcGz

An ELSI for AI: Learning from genetics to govern algorithms In the United States, the summer of 2025 will be remembered as artificial intelligence’s (AI’s) cruel summer—a season when the unheeded risks and dangers of AI became undeniably clear. Recent months h...

So what's the alternative to grantwashing you ask? We offer several ideas, including one by Alondra Nelson that borrows from the structure of the Human Genome project to dedicate 3-5% of R&D funding from emerging technologies to safety and ethics research.

www.science.org/doi/10.1126/...

Hey all, I reached out to the PO of my NIGMS MIRA to ask if the gov't shut down, and rescheduling of study sections, might allow for some accommodation to the standard rule that PIs cannot resubmit a MIRA while their MIRA (or other RPG) is under review (waiting in scores or summary statements) 🧪

Gene-specific selective sweeps are pervasive across human gut microbiomes - Nature Development and application of the integrated linkage disequilibrium score (iLDS) reveals both selective pressures impacting the human gut microbiome and the mechanisms by which gut bacteria adapt to ...

What a beautiful paper! www.nature.com/articles/s41...

Gene-specific selective sweeps are pervasive across human gut microbiomes - Nature Development and application of the integrated linkage disequilibrium score (iLDS) reveals both selective pressures impacting the human gut microbiome and the mechanisms by which gut bacteria adapt to ...

Grateful to share our paper on gene-specific selective sweeps in human gut microbiomes, now out in Nature! It has been a joy to work with @rwolff.bsky.social, whose insights and hard work made this possible.
www.nature.com/articles/s41...

The Influence of Demographic History and Genetic Architecture on Complex Traits via Runs of Homozygosity https://www.biorxiv.org/content/10.64898/2025.12.17.694908v1

Determining the driving factors shaping genetic architecture of complex traits in recently admixed populations Understanding the genetic architecture of complex traits in admixed populations remains challenging due to heterogeneous genetic backgrounds and demographic histories. Mischaracterizing admixture can ...

Preprint online right before the holidays! Excited to share the first piece of work from the Zhang Lab, led by my absolutely stellar postdoc Michelle Kim! In this work, we ask how admixture, selection and demography shape complex trait genetics and GWAS performance www.biorxiv.org/content/10.6...

Honestly, kinda makes it worth 1.5 bike rides to work🤷🏽‍♀️

🥲 BEST DAY EVER

We are thrilled to announce the first official release (v0.1.8) of #𝗯𝗲𝗱𝗱𝗲𝗿, the successor to one of our flagship tool, #𝗯𝗲𝗱𝘁𝗼𝗼𝗹𝘀! Based on ideas we conceived of long ago (!), this was achieved thanks to the dedication of Brent Pedersen.

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Plot of estimated exposure effect vs true exposure effect for naive estimate, GRM-corrected estimate in 4K individuals, PENGUIN-corrected estimate in 4K individuals, and PENGUIN-corrected estimate in 100K individuals. Genetic correlation between exposure and outcome is simulated at 0.5. Naive estimates are biased towards the genetic correlation between traits. Confidence intervals for GRM-corrected estimates are small and overlap the true effect, while PENGUIN-corrected estimates have 3-4X standard errors and do not always overlap the true effect in small sample sizes.

Table describing concerns about portability of GWAS summary statistics in test cohort. For GRM, concerns are "None; exposure effect can be estimated entirely within-sample for test cohort if genotype available". For PENGUIN, concerns are "Per-SNP heritability is assumed to be identical between GWAS and test cohort, but systematic differences can arise due to demographic history". For polygenic score, concerns are "Variants and effect sizes ascertained from GWAS cohort may not be useful predictors in test cohort when LD patterns or allele frequencies differ".

In small sample sizes and understudied populations, our GRM-based approach outperforms existing methods, all of which rely on GWAS summary statistics. Unlike GWAS, constructing GRMs does not require biobank-scale data, and in-sample GRMs are inherently robust to portability concerns. (5/6)

Observational epidemiological studies can mitigate genetic confounding with the genetic relatedness matrix Observational studies are commonly used in psychology and epidemiology to identify risk factors correlated with health outcomes. However, these studies are vulnerable to confounding when shared geneti...

Excited to share work from my postdoc with @docedge.bsky.social and collaborators Matt Pennell and @jgschraiber.bsky.social, newly out over the weekend: www.biorxiv.org/content/10.1... (1/6)