We're looking for a postdoc to join us in trying to map the routes by which different signals travel through plants and identify what information they carry. Link👇or get in touch! @johninnescentre.bsky.social
#PlantSciJobs
www.jic.ac.uk/vacancies/po...
New pre-print from the team!
The manuscript is @emma-raven.bsky.social's PhD work showing that whether a leaf is a carbon sink or a carbon source influences how they execute immune responses.
Have a read!
#PlantScience
@johninnescentre.bsky.social
This Halloween, we have a spooky evolutionary story for you.
The brainchild of @delaconcepcionjc.bsky.social, Nick Irwin and our fantastic collaborators is now out in @natplants.nature.com www.nature.com/articles/s41...
Here’s why I love this work — and why I think you’ll enjoy it too. 👇
We have a project available for 2026 NRP Doctoral Training Partnership entry (i.e. PhD studentship opportunity!)
How do cells communicate when it's hot?
Don't know? Me either! Come work with us @johninnescentre.bsky.social and figure it out
biodtp.norwichresearchpark.ac.uk/projects/how...
Super excited to see our work on the NLRseek program finally published 🥳 Here we identify new NLRs against major wheat pathogens and present a pipeline for NLR identification. Huge thank you to all of the co-authors for bringing this work together! @matthewmoscou.bsky.social rdcu.be/eIGvv
Excited to attend my 1st ISMPMI conference, and present our work on a paired wheat CNL/MLKL receptor mechanism! 🌾
Come chat to me at my poster on Tuesday, P-050! 📜
If you miss my poster session, I will be talking in: Crop resistance genetics and genomics on Wednesday - 16:25-16:35!
Shedding light on the structure-function mechanisms of LRR-RPs. Our research merges #AlphaFold3, years of literature and functional validation to reveal diverse ligand-binding mechanisms and a conserved co-receptor association mechanism. www.biorxiv.org/content/10.1...
Congratulations to @rvalenciaaz.bsky.social and his teammates who won the #AI track at @nucleate.bsky.social UK PlantHack with @aria-research.bsky.social. The 2-day hackathon brough together scientists from across the UK to reimagine UK agriculture with AI & synthetic biology.
Hi everyone! I’m new to Bluesky. At the beginning of the year, I moved to Zurich @UZH_en to start a postdoc with #CyrilZipfel and @pedrobeltrao.bsky.social, investigating protein phosphorylation in plants 🌱
If you’re nearby or working on something similar, let’s connect 😀
Next London Cell-free Biological Product Meeting:
🗓️ Monday, 16th June 2025 (1-5 pm)
📍 Imperial College London, South Kensington
✨ Keynote: Prof. Keith Pardee (Toronto)
Limited talk slots available
📝 Register: forms.office.com/e/dbW6hJacmS
#Cell-free #Biotech #ImperialCollege #UCL
Last night, the House of Lords debated Gene Edited plants.
Green party members spoke much nonsense, including likening GE to "a child dismantling a clock and throwing the pieces into a microwave to see what happens."
You can find a debate transcript here: www.theyworkforyou.com/lords/?id=20...
My group has newly joined Imperial, and I have a great team: Dr Molly Bergum, Charlotte Woolley, and Alexandra Butulan. We focus on the biosynthesis of natural products for the antimicrobials and resistance area, using both engineered microbes and cell-free systems @mollybergum.bsky.social
It is real! 🤩
I can touch it (after I printed it).
Huge Congrats to everyone involved! 😀
We're looking for a postdoc to join the lab to work on cell-to-cell communication via the apoplast. Candidate must be brave, as they will have to lead us (me) away from the plasmodesmata-lands we've inhabited for so long!
www.jic.ac.uk/vacancies/po...
Pls repost 🚨I'm looking for someone excited about #proteindesign and #synbio to join my lab @Durham_Uni
at the CPBM @cpbm-heddlelab.bsky.social
to undertake a PhD using #synthetic knottins as novel #bioinsecticides. If you're interested please get in touch and check out the advert below 👇
Big shoutout to the incredible women in our lab—you inspire us every day 💪
#WomenInScience #WomenInSTEM
I had great fun hosting this!
Huge thanks to the attendees for the really engaging session, everyone chipped in their effort and time (on a rainy evening). We can’t wait for the page we worked on to be out soon!
www.nature.com/articles/s41...
See our new review in Cell Death and Differentiation led by Matthew Wengler on regulated cell death in Magnaporthe @thesainsburylab.bsky.social
New review from Berlaine Quime and Lauren Ryder highlighting live cell imaging of plant infection. onlinelibrary.wiley.com/doi/full/10....
Some wonderful news for the UK bioeconomy!
UK presses ahead with gene editing plans despite EU warnings - on.ft.com/4gOyKQb via @FT
#plantgene
Thank you, Basti! ☺️ Grateful for your help!
Thank you to all collaborators — I'm really grateful for all the expertise, guidance, and hard work! A special thanks to @matthewmoscou.bsky.social, @pdchristine.bsky.social, @jackrhodes.bsky.social, @samwalds.bsky.social, Jan Sklenar, Hyeran Moon, and Cyril Zipfel. (8/8)
We predict that the EXO70FX clade has largely lost exocyst association and represents a novel acquisition that emerged during Poales diversification for immunity 🌾🦠🍄. (7/8)
We found that in addition to lacking structural requirements for exocyst complex formation, EXO70FX12 lacks exocyst subunit associations in yeast, Nicotiana benthamiana, and barley. (6/8)
We next used structural predictions to identify an unusual pattern in EXO70FX members. The N-terminal regions are highly divergent and often truncated compared to yeast EXO70 and other EXO70s shown to interact with the exocyst! (5/8)
EXO70FX12 belongs to the EXO70FX clade, which is found only in Poales, an order of monocots that includes all agriculturally important cereals 🌽🌾. EXO70FX has several striking features, including the most extreme degree of expansion and greatest intra-clade divergence. (4/8)
EXO70s are conserved across eukaryotes and generally serve as subunits within the exocyst, an octameric protein complex integral to vesicle trafficking. Unlike yeast and animals, plants carry many copies of diverse EXO70s, which experience lineage-specific expansions. (3/8)
We previously discovered that EXO70FX12 confers immunity to wheat stripe rust in conjunction with a leucine-rich repeat receptor kinase (PUR1) in barley (science.org/doi/10.1126/...). Surprisingly, EXO70FX12 has a novel role in immunity independent of the exocyst complex. (2/8)
Thrilled to share our work on an unusual EXO70 clade unique to grasses and grass-like species 🌾! (1/8)
www.biorxiv.org/content/10.1...
@thesainsburylab.bsky.social
An immune signalling holiday tale: A Poales-specific EXO70 clade doesn't fit in with the extended family. #PlantScience
