Rewiring the Budding Yeast Proteome using Synthetic Physical Interactions
Artificially tethering two proteins or protein fragments together is a powerful method to query molecular mechanisms. However, this approach typically relies upon a prior understanding of which two pr...
Studying protein-protein associations just got easier.
Synthetic Physical Interaction is a unique method for high-throughput screening that bypasses the need for individual yeast constructs.
Check out the full protocol by Guðjón Ólafsson & Peter Thorpe
doi.org/10.1007/978-...
#Genetics #ScienceSky
11.03.2026 15:01
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Webinar 2 pm Tuesday - navigating microbial diversity with PIXL Max. Accelerating your path from natural sample to microbial insight with faster automated colony picking.
tick marks on each: anaerobic chamber compatible, 3000 colonies / hour, bacteria, fungi, algae, AI colony detection & morphological classification. Images show the exterior of the picker (a white box with silver trim and a black door, the whie has cartoon images of colonies with different morphologies). image below shows a red picking head picking 6 colonies simultaneously from an agar plate to go into the target bays containing a 96 multi-well plate and a 96 deep well plate.
Come see our new high-speed🤖 automated colony picker in action online next Tuesday at 2PM GMT. Isolate and analyse the #microbiome at 3000 colonies/hour and AI colony detection & analysis. 🧪🧫
Spaces are filling up fast: tinyurl.com/28atthuk
06.03.2026 17:03
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Webinar: 2PM 10th March 2026. Accelerating your path from natural sample to microbial insight. Ticks in front of: Anaerobic Chamber compatible, 3000 colonies/hour, bacteria, fungi, algae, AI colony detection & morphological classification. Images show PIXL Max colony picker & it's picking head isolating 3 colonies from a red plate simultaneously
Manual isolation is the bottleneck in #NaturalProducts discovery. How do you turn 1000s of #Microbiome samples 🧫 into insights without losing months of lab time?
Join our webinar on March 10th at 2PM GMT to see the PIXL Max in action. 🏃♀️➡️
Register Here: tinyurl.com/28atthuk
04.03.2026 17:07
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Screenshot of a webinar call containing two women and a man. The first woman is enlarged - this is lindsay hall with ginger hair in a classic long bob with bangs sitting in front of a white background. The second woman is abi sparks - wearing Singer instruments branded clothing and sitting in front of a branded background that includes the colony picker PIXL. James chong is sat in the third window in his office filled with large green plants and plenty of windows.
Lindsay J Hall, James Chong and Abi Sparks delivered a stellar webinar last week on the Dark Matter of the Microbiome: How culturing the unculturable can help us solve real world problems.
If you missed it - don't worry it's still available on-demand. shorturl.at/mepmz
02.03.2026 16:48
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Webinar | The Dark Matter of the Microbiome. 2 PM February 24th 2026. With Professors Lindsay Hall & James Chong. How culturing the unculturable can help us solve real world problems. One poo at a time.
Last Chance to join the microbiome webinar - It’s tomorrow @ 2PM!
Register for one of the last spots here: tinyurl.com/2rr53m8j
Lindsay Hall & @jameschong.bsky.social present key insights on tackling the unique challenges of human #microbiome research. 🧫🧪
23.02.2026 13:57
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It’s a struggle to find reliable Anaerobic Chamber x Colony Picker combos. 🧫
Every PIXL is compact enough to fit into a range of anaerobic chambers🤖. Join Profs. Lindsay Hall and James Chong next week to discover how they scale up their #microbiome research. 🧪
Register here: tinyurl.com/2rr53m8j
18.02.2026 16:38
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Webinar: The Dark matter of the microbiome. 2 PM February 24th 2026 with Professors Lindsay Hall & James Chong. How culturing the unculturable can help us solve real world problems. One poo at a time.
Image at the top of the inside of PIXL (an automated colony picker) selecting a colony from an SBS agar plate with an array.
Below are two headshots of a Lindsay and James. And a QR code for registeration
What’s hiding in the "Dark Matter" of your samples? 🔍
Cultivation bottlenecks are the biggest hurdle in microbiome research.🤖🧫
In 7 days, Profs. Lindsay Hall and James Chong show us how to break through.
📍 24 Feb, 2PM GMT
Register here: tinyurl.com/xr58eb28
#Microbiome #Research🧪
16.02.2026 16:59
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Profs. James Chong & Lindsay Hall will be delivering you their key insights on how to culture the unculturable direct from their many years of struggle with the “Dark matter” of the microbiome. Register here 🧪https://tinyurl.com/xr58eb28🧫
#Webinar #LabLife #MicrobiomeSky #ScienceSky
13.02.2026 14:03
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Professor James Chong, University of York.
Expert at transforming anaerobic waste into renewable resources.
Join our webinar to learn:
How to overcome cultivation bottlenecks
Techniques for uncovering new insights
The latest updates on James' Research
The Dark Matter of the Microbiome
How culturing the unculturable can help us solve real world problems.
2PM February 24th 2026
with Profs. Lindsay Hall & James Chong
Prof. James Chong studies #microbiome communities in human waste, filtering the essential species from the coasters. With his 60 5L anaerobic digestion systems and a PIXL Dark🤖, James automates his characterisation🧫. The goal is to form a renewable stable source of biogas fuel🧪.
13.02.2026 14:02
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An adult Man and Woman stand behind a table watching as three older girls play with felt tip pens and spinners to create beautiful patterns.
A girl and a boy with brown hair in dark blazers sit facing away from the camera looking at a box labelled ColonyCam and a monitor with an image taken with ColonyCam showing. Beyond that are two banners on Science and STEM careers in microbiology.
A girl with curly brown hair in a dark blazer plays with felt tip pens and a spinner to create art on a table with a white tablecloth at an event. behind her sits a white box with a red camera icon.
Our BizDev Manager, had a great time this week at the Somerset Sustainable Futures event hosted by Somerset EBP. He meet students and teachers from local schools, to promote green education, sustainability, and careers. We take our Responsibility to science seriously and wish others to do the same.
13.02.2026 10:29
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Singer Instruments Microbiome webinar
Learn how lab automation via PIXL can help you uncover the mysteries of the microbiome.
Learn all about Lindsay & James' research and how their tackle their unique challenges in our webinar. With limited spaces filling up quick, secure your spot now: tinyurl.com/xr58eb28
11.02.2026 16:57
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Prof. Lindsay Hall, University of Birmingham. Expert at uncovering the secrets of the infant gut microbiome. Join our webinar to learn:
How to overcome cultivation bottlenecks
Techniques for uncovering new insights
The latest updates on Lindsay's Research.
The Dark Matter of the Microbiome
How culturing the unculturable can help us solve real world problems.
2PM February 24th 2026
with Profs. Lindsay Hall & James Chong
The volume of baby poop in Prof. Lindsay Hall’s freezers is incredible. 💩
Lindsay is highly regarded in human microbiome research and a leader in the infant gut #microbiome space. She and Prof. @jameschong.bsky.social will be delivering you key insights on how to culture the unculturable.
11.02.2026 16:55
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Our mission is powered by the brilliant women on our team. 🧪
Today, we’re celebrating their contributions to science while advocating for the pay, recognition, and career equity they deserve. We couldn't do it without them!
#WomenInScienceDay #WomenInSTEM
11.02.2026 12:53
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Image of the PIXL colony picker hovering over a plate of colonies. below is the following text: Webinar | The Dark Matter of the microbiome. 2pm February 24th 2026 with Professors Lindsay Hall and James Chong. How culturing the unculturable can help us solve real world problems. One poo at a time. bottom right is a QR code.
What’s hiding in the "Dark Matter" of the #microbiome?
We’re hosting research experts Prof. Lindsay Hall & Prof. James Chong to dive into: 🧫 Overcoming cultivation hurdles 🦠 New insights from human waste samples 🧪 Research strategies from the experts
Register here: tinyurl.com/xr58eb28
#LabLife
09.02.2026 16:15
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Patrick Cai stands in a casual suit on stage giving a seminar talk. behind him is a presentation on the intersecting emerging technologies including an image of the PIXL colony picker that he uses for automating the Sc2.0 project.
High-throughput synthetic genomics comes to the Earlham Institute! 🧬
Prof. Patrick Cai shared updates on the Sc2.0 project to rewrite the yeast genome from scratch. An outstanding example of using automation like the PIXL in synthetic biology.
#ALife #MicroSky #SynBio
09.02.2026 13:04
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Half the image is a closeup of filamentous colonies outline in green (in detail) and circular colonies outlined in purple. On the right is a white legend stating All features (red tick) 12, Circular (purple tick) 5 colony cluster 0, filamentous shape (green tick) 7, irregular 0, punctate 0.
Who wants to struggle with ImageJ thresholds? Simple tools fall short on irregular or filamentous morphologies. Automatically detect, quantify and isolate a diverse array of colonies with PIXL Max AI colony detection & morphological classification - perfect for the #microbiome. No need to optimise.
06.02.2026 13:43
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Somerset Business Awards 2026 Finalist. Including the pink/purple ombre leaf logo.
We're a finalist for the Somerset Business Awards 2026 Employer of the Year!
Thank you to everyone a who's worked so hard this year and especially to those who spoke to the judges about what life is like as a certified NERD 🤖.
#SBA2026 #Somerset #Business
05.02.2026 15:56
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Collage of photos depicting teenage students in green uniform from The castle school sitting across a small square table being interviewed by working professionals.
Project Manager Ayo and Scientist Emmy recently participated in the Castle School's mock interview session. The experience provided students with a realistic taste of professional life through targeted questions on teamwork and resilience.
#STEM #Outreach #Education
05.02.2026 09:22
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We can talk about who won the Traitors But can we talk about life on a therapy waiting list? Brave the big talk. Image of a black bob wig with solid bangs on a bright pink background.
Join the nation's biggest mental health conversation. Talking helps reduce stigma and can make people feel comfortable enough to seek help when they need it. MIND is encouraging us to brave the big conversations, the ones that still feel unspoken. Let someone know they're heard this #TimeToTalkDay.
04.02.2026 15:40
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Why should robots be simple video thumbnail. An interview with Harry Singer - CEO of Singer Instruments.
The most expensive lab instrument🤖? The one gathering dust because only the retired tech knew the “dark art” of using it. We build tech that you can actually use. You can master 90% of PIXL Max’s functionality in under 10 minutes!
Watch the full video here: tinyurl.com/95jbjekv
#microbiology 🧪
04.02.2026 10:27
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Webinar: The Dark matter of the Microbiome. 2 pm February 24th 2026. Profs. James Chong & Lindsay Hall will be speaking on How culturing the unculturable can help us solve real world problems. One poo at a time.
#Microbiome legends Prof. Lindsay Hall & James Chong are diving deep into their gut microbiome research strategies. We’ll be tackling cultivation bottlenecks and investigating techniques to scale #Microbiology insights from human waste. 💩🧫
Join us here: tinyurl.com/xr58eb28
03.02.2026 16:17
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An image of a petri dish containing colonies, captured on PIXL Max. Thousands of colonies on the image have been recognised by the AI colony detection algorithm
Colony detection is easy when you have eyes - but computers have algorithms that look for patterns 🧫. Microbiology almost never fits a perfect pattern. PIXL Max AI colony detection 🤖, with its high definition camera, can isolate colonies down to 0.2 mm and classify their morphology!
#MicroSky
03.02.2026 14:07
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Speed doesn’t matter, unless you’re the bottleneck in a high-throughput lab🤖. We’ve spent the last year quietly slaving away to please the speed queens with the PIXL Max at 3000 colonies/hour🦠🧫. Of course we added a few side quests as well - what else is new?
#MicroSky #LabAutomation #SciSky
30.01.2026 14:57
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Automated Colony Picking with PIXL Max
YouTube video by Singer Instruments
It's been <1 week of PIXL Max, and WOW!
Published twice - thanks Lab Manager & the Microbiologist
700+ emails - our inbox is buzzing 🧫
1000s LinkedIn impressions - we see you watching 🤖
1 big celebratory pub sesh - essential to any Singer launch. 🍻
Watch PIXL Max speed along: tinyurl.com/2ewtpff3
29.01.2026 15:13
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6 agar SBS format PlusPlates containing arrays of 384 Chlamydomonas colonies each. These were created by automated colony picker PIXL. Some of the colonies have grown to about 1 mm diameter, others have not grown.
My plate didn’t grow? Now I have to do it all over again…AGAIN! 98% transfer efficiency sounds great, but 99.78% is even better when you’re picking the entire 🧪CLiP 2 mutant library🦠
(71, 700 colonies). It’s the difference between 1434 missed colonies, and only 148 missed. 🤖
28.01.2026 12:06
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PIXL Max, precision colony picker, uses 3/6 of it's picking heads to isolate from a dense and diverse agar plate.
Pick any colony at 98% transfer efficiency 🤖 - but only with these specific pins at £££/pin. Absolutely NOT! One Pinpoint Picking Technology to rule them all. Bacteriophage, Aspergillus, Chlamydomonas, and so many different types of fungi all with one sterile picking filament!🦠🧪🧫
26.01.2026 11:08
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Faster, Smarter, Precision Colony Picking
PIXL MAX (logo)
3000 colonies per hour
AI intelligence
Advanced Detection
Discover Here: QR code (bottom right hand corner)
All on a black background, written in white , except the PIXL Max logo which is in Singer Red.
The bottom left hnad corner contains an image of the PIXL Max colony picker. Thisis a large white box with a black sliding door. The white box is covered in artist impressions of colonies in varying morphologies.
Introducing PIXL Max🤖: our fastest automated colony picker yet with AI powered detection and analysis of microbes and zones of inhibition and super hi-res optics to detect the tiniest details of your colony morphologies.
23.01.2026 10:21
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