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Amanda Alker

@atp-alker

Marine microbiologist | Assistant professor at the University of Rhode Island | Postdoc - Rubin & Doudna Labs UC Berkeley | Symbiosis, bacterial genetics and microbiome editing Alkerlab.weebly.com

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04.09.2023
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Latest posts by Amanda Alker @atp-alker

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🚒 After 50 years of service, R/V Endeavor departed Narragansett for the final time.

From its home port at URI's Bay Campus, the ship carried thousands of scientists, students, engineers, and technicians to sea, supporting 736 research cruises and traveling more than one million miles. 🌊 πŸ§ͺ

09.03.2026 19:57 πŸ‘ 11 πŸ” 2 πŸ’¬ 2 πŸ“Œ 2

An REU internship at BIOS was a critical experience that shaped my career path. Highly recommend!

02.03.2026 03:09 πŸ‘ 3 πŸ” 0 πŸ’¬ 0 πŸ“Œ 0
A line graph showing NSF grant awards made through 2/27/26 for fiscal year 2026 compared with grant awards for fiscal years 2021-2025 for the Directorate of Biological Sciences.

A line graph showing NSF grant awards made through 2/27/26 for fiscal year 2026 compared with grant awards for fiscal years 2021-2025 for the Directorate of Biological Sciences.

2/10

01.03.2026 14:48 πŸ‘ 116 πŸ” 33 πŸ’¬ 4 πŸ“Œ 7
PearTree β€” Phylogenetic Tree Viewer

So I pleased to announce the conceptual spawn of FigTree: PearTree (acronym still to be finalised). If you want to dive right in it is hosted as a web app here: artic-network.github.io/peartree (click the β€œExample...” button for immediate candy and then click every button you can find).

28.02.2026 19:01 πŸ‘ 163 πŸ” 100 πŸ’¬ 5 πŸ“Œ 4
10th European Society for Evolutionary Developmental Biology Meeting 2026 The European Society for Evolutionary Developmental Biology is delighted to welcome you to the 10th biennial meeting, to be held at the University of Glasgow from June 9th - 12th in 2026.

Thomas Bosch and I have organized a symposium on the β€œImpacts of Microbiota on Animal and Plant Development” that will be part of the Euro EvoDevo meeting in Glasgow this summer. Please register through EED. Thanks to generous sponsors, we have some financial support for early-career scientists.

17.02.2026 16:05 πŸ‘ 4 πŸ” 1 πŸ’¬ 0 πŸ“Œ 1

Permission granted! I’m a bit sore but also was itching to move after being cooped up!

24.02.2026 00:11 πŸ‘ 1 πŸ” 0 πŸ’¬ 1 πŸ“Œ 0

6pm Monday 2/23 - Green Hill, South Kingstown RI

Gusts and heavy snow have dissipated.

23.02.2026 23:29 πŸ‘ 5 πŸ” 1 πŸ’¬ 3 πŸ“Œ 0

Koonin's lab in NIH is looking for postdocs. If you know someone who is interested, please spread the word. The details about the position are below: www.training.nih.gov/jobs/pdf-ecb...

17.02.2026 19:36 πŸ‘ 18 πŸ” 21 πŸ’¬ 0 πŸ“Œ 0
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"All T6SS-inducing regulators are equal, but some regulators are more equal than others".
Preprint 🚨: We use #Vibrio to show that #T6SS activation by regulator manipulation may result in the expression of different effector repertoires, affecting toxicity 🦠
www.biorxiv.org/content/10.6...

12.02.2026 09:53 πŸ‘ 13 πŸ” 8 πŸ’¬ 1 πŸ“Œ 0
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Happy birthday to one of my favourite haters, Charles Darwin

12.02.2026 16:31 πŸ‘ 10352 πŸ” 3081 πŸ’¬ 162 πŸ“Œ 419

Phylogenetically distinct Vibrio mediterranei lineages confer robust protection under thermal stress against oyster pathogens https://www.biorxiv.org/content/10.64898/2026.02.09.704869v1

10.02.2026 02:17 πŸ‘ 0 πŸ” 1 πŸ’¬ 0 πŸ“Œ 1

CAZyme domain architectures suggest fine-scale functional differentiation among anaerobic fungi and bacteria during lignocellulose conversion to volatile fatty acids https://www.biorxiv.org/content/10.64898/2026.02.09.704939v1

11.02.2026 03:17 πŸ‘ 0 πŸ” 1 πŸ’¬ 0 πŸ“Œ 0
Building the Marine Probiotic Platform: Developing a High-Throughput Process to Discover Coral Probiotics for Stony Coral Tissue Loss Disease Stony coral tissue loss disease (SCTLD) is a deadly, waterborne coral disease. Since 2014, SCTLD has spread throughout Florida's Coral Reef and is now confirmed in 28 Caribbean countries and…

Check out our recent preprint about our Coral Probiotics Discovery Platform!
www.biorxiv.org/content/10.6...

13.01.2026 01:57 πŸ‘ 4 πŸ” 2 πŸ’¬ 0 πŸ“Œ 0

Check out this cool new preprint from @therubinlab.bsky.social led by @jnvmartinson.bsky.social

They shielded recipient strains from lethal zygosis (conjugative killing of the recipient) by encoding protective DNA cargo via CASTs πŸ§ͺ🦠🧬🧫

11.02.2026 04:55 πŸ‘ 10 πŸ” 4 πŸ’¬ 0 πŸ“Œ 0
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NEW: Registration is now FREE for graduate students and postdocs for the 14th Annual Yosemite Symbiosis workshop. THANKS to the Gordon and Betty Moore Foundation! Space is limited. Learn more and REGISTER here: snri.ucmerced.edu/form/symbios...

08.02.2026 17:29 πŸ‘ 16 πŸ” 13 πŸ’¬ 0 πŸ“Œ 0

Big deal! Congrats friend, can’t wait to see what you do during this next stage!

03.02.2026 12:24 πŸ‘ 0 πŸ” 0 πŸ’¬ 0 πŸ“Œ 0
Aeromonas adhesins facilitate kin and non-kin attachment to enable T6SS-mediated antagonism in liquid Bacterial ability to deploy the type VI secretion system (T6SS) against rivals requires prolonged cell-cell interactions. Such interactions are facilitated on solid surfaces but are assumed to be absent in liquid, leading to the conventional dismissal of T6SS-mediated competition in liquid environments. Here, we find that Aeromonas jandaei employs its T6SS to eliminate diverse bacterial competitors in liquid media. Using a workflow that monitors interbacterial competition via prey luminescence, we demonstrate that auto-aggregation and co-aggregation, facilitated by distinct adhesins, enable kin and non-kin recognition and intoxication in a T6SS-dependent manner. Furthermore, we show that another marine bacterium, Vibrio coralliilyticus , employs T6SS to intoxicate rivals in liquid media. Collectively, our results indicate that T6SS-mediated competition in liquid is more common in marine bacteria than previously anticipated, and can be facilitated by diverse molecular mechanisms that govern cell aggregation. ### Competing Interest Statement The authors have declared no competing interest. Israel Science Foundation, https://ror.org/04sazxf24, 1362/21, 2174/22 Swiss National Science Foundation, 51NF40_180541

It is widely accepted that #T6SS -mediated intoxication occurs only on solid surfaces, where prolonged cell-cell interactions are forced, and not in liquid environments. But is this generalization true? Our new preprint says it isn't. A 🧡 ...
biorxiv.org/content/10.6...
🦠

28.01.2026 12:36 πŸ‘ 28 πŸ” 13 πŸ’¬ 3 πŸ“Œ 0
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Postdoctoral position - Synthetic Biology / Bacterial Immunity - Research The Bikard lab at Institut Pasteur in Paris is seeking to hire postdoctoral researchers. We are investigating bacteria / bacteriophages interactions, and the genetic innovation that happens at this in...

🚨 Hiring Alert! 🚨My lab at Institut Pasteur is recruiting several Postdocs! We have exciting open projects in: 🦠 Synthetic Biology andπŸ›‘οΈ Bacterial Immunity. Come do great science with us in the middle of Paris! πŸ‡«πŸ‡·πŸ₯ research.pasteur.fr/en/job/postd...

28.01.2026 11:19 πŸ‘ 74 πŸ” 81 πŸ’¬ 0 πŸ“Œ 2

Creation of Novel Methylating Conjugal Donor Strains for Genetically Recalcitrant Bacteria https://www.biorxiv.org/content/10.64898/2026.01.22.701203v1

23.01.2026 10:17 πŸ‘ 1 πŸ” 1 πŸ’¬ 0 πŸ“Œ 0
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Cell cycle dysregulation of globally important SAR11 bacteria resulting from environmental perturbation - Nature Microbiology Without key cell cycle control genes, SAR11 cells experience aneuploidy and growth inhibition when exposed to changes in nutrients, carbon sources or temperature stress, a vulnerability that may repre...

Our latest. Led by the very talented @ahoiching.bsky.social

Cell cycle dysregulation of globally important SAR11 bacteria resulting from environmental perturbation www.nature.com/articles/s41... #jcampubs 🌊

22.01.2026 14:24 πŸ‘ 52 πŸ” 33 πŸ’¬ 3 πŸ“Œ 3
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Deadline is approaching (Feb 9) to apply for a PI position at Institut Pasteur. Come join us and contribute to an amazing scientific environment!!!

19.01.2026 16:55 πŸ‘ 17 πŸ” 31 πŸ’¬ 1 πŸ“Œ 0

Genetic biosensor for optimizing double-stranded RNA production by bacterial symbionts https://www.biorxiv.org/content/10.64898/2026.01.18.700149v1

19.01.2026 04:02 πŸ‘ 0 πŸ” 1 πŸ’¬ 0 πŸ“Œ 0
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Phylogeny‐Aware Metabologenomics Accurately Assigns Natural Products to Biosynthetic Gene Clusters We report a statistical approach for associating biosynthetic gene clusters with their cognate metabolites and demonstrate its unprecedented power for scalable natural product discovery. Notably, it ...

Phylogeny-Β­ Aware Metabologenomics Accurately Assigns
Natural Products to Biosynthetic Gene Clusters

@microbiotech.bsky.social by Judith Boldt et al from Ulrich NΓΌbel and @drrolfmueller.bsky.social

enviromicro-journals.onlinelibrary.wiley.com/doi/pdf/10.1...

18.01.2026 13:24 πŸ‘ 29 πŸ” 7 πŸ’¬ 0 πŸ“Œ 0
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Research Technologist - Life Sciences Advance Professional - Bordenstein Lab APPLICATION INSTRUCTIONS: CURRENT PENN STATE EMPLOYEE (faculty, staff, technical service, or student), please login to Workday to complete the internal application process. Please do not apply here, a...

πŸ“’ JOB OPPORTUNITY We are hiring a Research Technologist (Advanced Professional) to design, implement, support, analyze, and report on rigorous research in genetics, entomology, and host-microbe interactions. Please consider and share with others in need.

psu.wd1.myworkdayjobs.com/PSU_Staff/jo...

17.01.2026 23:00 πŸ‘ 10 πŸ” 21 πŸ’¬ 1 πŸ“Œ 0
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NSF seeks public input on its Fiscal Year (FY) 2026–2030 NSF Strategic Plan

The NSF strategic plan FY 2026-30 is available for public comment until Jan 27. Please make your voice heard! www.nsf.gov/od/updates/n...

17.01.2026 23:12 πŸ‘ 13 πŸ” 14 πŸ’¬ 0 πŸ“Œ 0
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Approaches for accelerating microbial gene function discovery using artificial intelligence - Nature Microbiology In this Review, the authors discuss how artificial intelligence can aid microbial gene function discovery.

Approaches for accelerating microbial gene function discovery using artificial intelligence www.nature.com/articles/s41... #jcampubs

07.01.2026 17:34 πŸ‘ 9 πŸ” 7 πŸ’¬ 0 πŸ“Œ 0
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Revealing the pervasive landscape of MGE-host interactions in situ with single-cell genomics Mobile genetic elements (MGEs), including plasmids and viruses, drive microbial evolution and ecosystem dynamics, yet their distribution, host range, and functions remain poorly understood, especially...

New preprint out: Revealing the pervasive landscape of MGE-host interactions in situ with single-cell genomics
www.biorxiv.org/content/10.6...

@mingyan-igi.bsky.social

07.01.2026 22:20 πŸ‘ 33 πŸ” 11 πŸ’¬ 0 πŸ“Œ 0

πŸ§ͺ🦠🧫🧬

06.01.2026 02:28 πŸ‘ 1 πŸ” 0 πŸ’¬ 0 πŸ“Œ 0
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Identification of proteins influencing CRISPR-associated transposases for enhanced genome editing Whole-genome screening reveals strategies to boost CRISPR-associated transposase genome editing efficiency.

#microsky #synbiosky

www.science.org/doi/10.1126/...

02.01.2026 10:36 πŸ‘ 22 πŸ” 12 πŸ’¬ 0 πŸ“Œ 0

During my postdoc in @therubinlab.bsky.social, @leosong.bsky.social and I aimed to make CRISPR-associated transposons more efficient for editing bacteria.

Couldn’t have done it w/o a CAST of characters at IGI and beyond @innovativegenomics.bsky.social, @cresslab.bsky.social, @doudna-lab.bsky.social

05.01.2026 21:39 πŸ‘ 25 πŸ” 11 πŸ’¬ 1 πŸ“Œ 0