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Fabrice Senger

@senger

Mechanobiology / Multi-cellular assemblies

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18.09.2023
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Latest posts by Fabrice Senger @senger

bonjour !

11.03.2026 11:55 πŸ‘ 0 πŸ” 0 πŸ’¬ 1 πŸ“Œ 0

Let's get ready for a full month of training in image analysis in @pasteur.fr , this summer!

Are you interested in learning how to do bioimage analysis? For light microscopy? for cryo-EM? And for cellular cryo-EM?

Stay tuned, Pasteur offers access to THREE courses, this June.

πŸ‘‡πŸŽ“

09.03.2026 16:23 πŸ‘ 29 πŸ” 28 πŸ’¬ 3 πŸ“Œ 0
a printed object showing the layer lines. On the bottom how to replicate those lines in PDMS to make a microfluidic device

a printed object showing the layer lines. On the bottom how to replicate those lines in PDMS to make a microfluidic device

the microfluidic channels

the microfluidic channels

Do you know those annoying layer lines you get with FDM 3D printers? Those layers you try to avoid or hide?Β 
What if I tell you we can use them to make 15-micrometer-tall microfluidic channels?
chemrxiv.org/doi/full/10.... 1/5 #chemsky the

09.03.2026 11:29 πŸ‘ 22 πŸ” 9 πŸ’¬ 3 πŸ“Œ 2

A must watch smart microscopy talk! πŸ™πŸ€©

09.03.2026 10:38 πŸ‘ 6 πŸ” 2 πŸ’¬ 0 πŸ“Œ 0
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I had a great time at Uni Copenhagen giving a talk about How Generative AI impacts Bio-Image Data Science this week. You find my slides online and a recording will be shared soon!
doi.org/10.5281/zeno...

Big thanks to @danishbioimaging.bsky.social, @claraprats.bsky.social and team for hosting me!

07.03.2026 08:55 πŸ‘ 12 πŸ” 4 πŸ’¬ 1 πŸ“Œ 0
A cochlea imaged in light-sheet microscopy (right) with staining for spiral ganglion neurons (red) and inner hair cells (blue). You will develop AI-based methods to analyze these structures, for example via segmentation of the individual cells (right) that will support gene therapy development for hearing loss and a better overall understanding of the anatomy of hearing.

A cochlea imaged in light-sheet microscopy (right) with staining for spiral ganglion neurons (red) and inner hair cells (blue). You will develop AI-based methods to analyze these structures, for example via segmentation of the individual cells (right) that will support gene therapy development for hearing loss and a better overall understanding of the anatomy of hearing.

Looking for a PhD position at the intersection of AI, imaging, and gene therapy? Apply for this position in my lab: tinyurl.com/2a2v6tvx

Part of sfb1690.uni-goettingen.de to study hearing, vision, and more.

Plus, you can create pretty pictures as the one below :).

05.03.2026 10:25 πŸ‘ 20 πŸ” 14 πŸ’¬ 0 πŸ“Œ 1
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New preprint out!
In this study, we introduce NanoFLex, a strategy that combines #HaloTag variants with #nanobodies -based immunolabeling to enable rapid, OneStep-IF #lifetime #multiplexing. Possible due to SmartSecondaries fused to #HaloTag from @nanotag.bsky.social: www.biorxiv.org/content/10.6...

04.03.2026 10:11 πŸ‘ 72 πŸ” 37 πŸ’¬ 1 πŸ“Œ 3
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Appose processing hackathon with @jytinevez.bsky.social, @ctrue.bsky.social, @gaellel.bsky.social, @strigaud.bsky.social, Carlos and Thomas . Simple POC with Java calling python through Appose to flip blocks. Promising!

02.03.2026 17:19 πŸ‘ 23 πŸ” 5 πŸ’¬ 0 πŸ“Œ 0

PAPER OUT ✨ How can we make smart microscopy more interoperable? What are the technical and cultural challenges? 30+ people from academia and industry propose a roadmap: doi.org/10.1515/mim-... Also a review of applications and repo of implementations. Join the discussion! smartmicroscopy.github.io

03.03.2026 17:32 πŸ‘ 45 πŸ” 17 πŸ’¬ 2 πŸ“Œ 1

Does anyone know of an anti mStayGold antibody that works for immunoblots / IP? Anyone tried the one from HUABIO (not even sure that’s a real company)? Thanks!

04.03.2026 01:38 πŸ‘ 1 πŸ” 10 πŸ’¬ 2 πŸ“Œ 0

Morphological parameters can capture emergent properties of dynamic disordered cytoskeletal networks https://www.biorxiv.org/content/10.64898/2026.03.01.708800v1

03.03.2026 11:47 πŸ‘ 1 πŸ” 1 πŸ’¬ 0 πŸ“Œ 0
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Yang, H., Meyer, F., Huang, S., Yang, L., Lungu, C., Olayioye, M. A., Buehler, M. J., & Guo, M. (2024). Learning collective cell migratory dynamics from a static snapshot with graph neural networks. PRX Life 2, 043010. #EpithelialMechanics
doi.org/10.1103/PRXL...

03.03.2026 08:00 πŸ‘ 10 πŸ” 3 πŸ’¬ 0 πŸ“Œ 0
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#ImageOfTheMonth March 2026
Dividing Arabidopsis epidermal cells imaged by confocal microscopy after expansion. Microtubules guided cell plate formation revealed in 3D with depth-code.
Image: Magali Grison @lbm-bordeaux.bsky.social @gtexm.bsky.social
#Microscopy #PlantScience #CellBiology

02.03.2026 14:36 πŸ‘ 26 πŸ” 10 πŸ’¬ 0 πŸ“Œ 0
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Excited to share our new paper (CVPR 2026 πŸš€): "MuViT: Multi-Resolution Vision Transformers for Learning Across Scales in Microscopy" which enables local predictions to use global context.
Great work led by @albertdm.bsky.social & another fun collab w @gioelelamanno.bsky.social! @scadsai.bsky.social

02.03.2026 13:42 πŸ‘ 64 πŸ” 28 πŸ’¬ 1 πŸ“Œ 2
A brief introduction to the use of containers for reproducible image analysis with Dr Martin Jones
A brief introduction to the use of containers for reproducible image analysis with Dr Martin Jones YouTube video by CCP-volumeEM

Our first 'Show & Tell Series' webinar, presented last week, is now available on YouTube.

Watch here: www.youtube.com/watch?v=E-pi...

We hope it’s useful to the community - please share with anyone who may be interested #VolumeEM #Bioimaging

02.03.2026 11:16 πŸ‘ 10 πŸ” 5 πŸ’¬ 0 πŸ“Œ 0
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Combined assembloid modeling and 3D whole-organ mapping captures the microanatomy and function of the human fallopian tube Tunable assembloid modeling and CODA tissue mapping, in tandem, design a tissue-validated in vitro model of the fallopian tube.

I think there is a need for a complete re-think for organoid modeling.

As long as the architecture of organoids that you produce is not directly compared to a 3D map of the organ (say, a fallopian tube) or disease to be modeled, it will be approximate.

More here: www.science.org/doi/full/10....

01.03.2026 20:17 πŸ‘ 42 πŸ” 7 πŸ’¬ 1 πŸ“Œ 1

Interested in doing a PhD in tumor mechanobiology?

At UniversitΓ© Paris-Saclay, the upcoming PhD selection process is open, and I’m looking to put forward a candidate to join my lab.

If you’re excited about uncovering how mechanical signals regulate tumor progression, please get in touch!

24.02.2026 13:08 πŸ‘ 13 πŸ” 11 πŸ’¬ 0 πŸ“Œ 0
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AI offers way to image and assess clinical cell samples The use of artificial intelligence in the clinic to image slides of cells enables the rapid assessment of cellular characteristics that might help with diagnostic decisions.

Nature news & views:
'AI offers way to image and assess clinical cell samples'
www.nature.com/articles/d41...

28.02.2026 08:02 πŸ‘ 4 πŸ” 2 πŸ’¬ 0 πŸ“Œ 0

Great visual guide for how to make interpretable plots in R.

28.02.2026 10:52 πŸ‘ 4 πŸ” 1 πŸ’¬ 0 πŸ“Œ 0
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When vessel constriction fails: Cellular mechanics linking developmental remodeling to vascular malformations

Happy to share a write-up of our recent publication @natcomms.nature.com demonstrating
how circumferential actomyosin-driven endothelial cell contractions constrict vessel diameter, providing insights into mechanisms of normal vessel remodelling and CCM.
www.bdr.riken.jp/en/news/rese...

26.02.2026 00:48 πŸ‘ 38 πŸ” 10 πŸ’¬ 3 πŸ“Œ 3

Finally!! Our Roadmap for Interoperability in Smart Microscopy is now published in #MethodsinMicroscopy @degruyterbrill.bsky.social
πŸ‘‰ check it out: doi.org/10.1515/mim-...

26.02.2026 13:20 πŸ‘ 6 πŸ” 1 πŸ’¬ 0 πŸ“Œ 0
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Check out our new paper!

iCLAP: an innovative method for integrable codetection
of low-abundance antigens with highplex
immunostaining

Read more about iCLAP here: www.nature.com/articles/s41...

26.02.2026 03:08 πŸ‘ 22 πŸ” 12 πŸ’¬ 1 πŸ“Œ 0
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Mountain, blush sky and snow

25.02.2026 09:42 πŸ‘ 1 πŸ” 0 πŸ’¬ 0 πŸ“Œ 0
Interactive 3D Visualization of Multiple Volumes & Shapes in FIJI (BigVolumeBrowser)
Interactive 3D Visualization of Multiple Volumes & Shapes in FIJI (BigVolumeBrowser) YouTube video by Johanna M. Dela Cruz

In the #BigVolumeBrowser news, there is a new awesome video tutorial about it made by certified magician Johanna M. Dela Cruz.
Check it out: www.youtube.com/watch?v=c0fr... (1/2)

24.02.2026 22:01 πŸ‘ 20 πŸ” 10 πŸ’¬ 3 πŸ“Œ 0
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Our BehaveAI paper has just come out!

Easy & effective tracking & behavioural classification, even with tiny (2px), fast moving, camouflaged objects.

Paper: doi.org/10.1371/jour...
Download: github.com/troscianko/B...

@uniexecec.bsky.social @kevinjgaston.bsky.social @jimamclgalloway.bsky.social

21.02.2026 09:02 πŸ‘ 87 πŸ” 36 πŸ’¬ 4 πŸ“Œ 1
Self-driving microscopes
Self-driving microscopes YouTube video by Cephla

How self-driving cars motivated us to build a universal diagnostics platform for malaria/Tb. The arc of technology is unpredictable at best.

m.youtube.com/watch?v=gbeg...

19.02.2026 06:17 πŸ‘ 15 πŸ” 6 πŸ’¬ 0 πŸ“Œ 0

Congratulations @ivaskalab.bsky.social team for this study on the role of vibration in vocal cord cancer! Was a fun collaboration 🎀🎀

20.02.2026 16:16 πŸ‘ 8 πŸ” 6 πŸ’¬ 0 πŸ“Œ 0
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LΓ₯ng, E., LΓ₯ng, A., Blicher, P., Rognes, T., Dommersnes, P. G., & BΓΈe, S. O. (2024). Topology-guided polar ordering of collective cell migration. Science advances, 10(16), eadk4825. #EpithelialMechanics doi.org/10.1126/scia...

19.02.2026 22:30 πŸ‘ 7 πŸ” 2 πŸ’¬ 0 πŸ“Œ 1
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On the occasion of International Women’s Day at @crg.eu, we are pleased to welcome :

Marie-Γ‰milie Terret (CIRB, @college-de-france.fr), who will speak on
β€œMechanics of Oocyte Divisions”

Hosted by @adelaljord.bsky.social

πŸ“… When? Monday, March 9th, 2026 - 12:00–13:00 - Aula Room, @prbb.org

19.02.2026 08:27 πŸ‘ 12 πŸ” 5 πŸ’¬ 0 πŸ“Œ 0
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Thanks for highlighting our work on combining AI-based organelle dynamics detection in phase contrast with fluorescence!

www.nature.com/ncomms/edito...

@natcomms.nature.com and Nelio Rodriguez. Spearheaded by @wl-stepp.bsky.social with collaborators @jclandoni.bsky.social @maweigert.bsky.social

19.02.2026 06:52 πŸ‘ 27 πŸ” 11 πŸ’¬ 0 πŸ“Œ 0