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Ayushi Rehman

@ayushirehman

Juggling paralogs for PhD! Interested in gene regulation, RNA Biology, Neurodegenerative disorders. Fiction lover πŸ§™πŸ”! RBP-Lab @IITGuwahati

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12.11.2024
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Latest posts by Ayushi Rehman @ayushirehman

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My fantastic department at CU Boulder is hiring a tenure-track Assistant Professor! This is a broad search spanning nearly all areas of biology. Applications are due Nov 13, 2025. Feel free to reach out to me with questions, and please share widely.
jobs.colorado.edu/jobs/JobDeta...

17.10.2025 15:59 πŸ‘ 37 πŸ” 39 πŸ’¬ 0 πŸ“Œ 0
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Induction of menstruation in mice reveals the regulation of menstrual shedding During menstruation, an inner layer of the endometrium is selectively shed, while an outer, progenitor-containing layer is preserved to support repeated regeneration. Progress in understanding this co...

I’m thrilled to share my postdoc work and the first paper from the McKinley Lab! πŸŽ‰
@karalmckinley.bsky.social
We built the first transgenic model of menstruation in mice.
We used it to uncover how the endometrium organizes and sheds during menstruation. πŸ§ͺ
www.biorxiv.org/content/10.1...
🧡

10.10.2025 12:50 πŸ‘ 232 πŸ” 83 πŸ’¬ 14 πŸ“Œ 15
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Fred Hutchinson Cancer Center Fred Hutch is dedicated to the elimination of cancer and related diseases as causes of human suffering and death.

My awesome Drosophila colleague Akhila Rajan at Fred Hutch (Seattle) is recruiting both a staff scientist and a postdoc to study fat–brain communication, innate immunity, mitochondrial signaling, and brain senescence. Great team, great environment. Apply here: careers-fhcrc.icims.com/jobs/30062/j...

17.09.2025 01:05 πŸ‘ 46 πŸ” 37 πŸ’¬ 0 πŸ“Œ 1

Willing to join us @pasteur.fr for a PhD for a project on how interactions between mobile genetic elements shape bacterial adaptation? Subject to be tailored to candidates with keen interest in evolution, genomics, computational biology, microbiology. Check www.pasteur.fr/en/education...

08.09.2025 08:56 πŸ‘ 45 πŸ” 57 πŸ’¬ 0 πŸ“Œ 0

🍽️🧬 How do diet and gut microbes shape fertility across generations? πŸͺ±πŸ”¬ Our Laboratory at #InstitutPasteur is recruiting a PhD student to study epigenetic inheritance of fertility using C. elegans. Fully funded via the International PPU program. Apply now! 🌍 #PhDposition #Epigenetics #Inheritance

07.09.2025 10:49 πŸ‘ 24 πŸ” 19 πŸ’¬ 0 πŸ“Œ 2
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Multivalent interactions with CCR4–NOT and PABPC1 determine mRNA repression efficiency by tristetraprolin - Nature Communications Deadenylation leads to mRNA decay, with PABPC1 protecting the poly(A) tail, while tristetraprolin and CCR4–NOT promote deadenylation. Here, the authors describe how these three proteins interact to re...

Delighted to present our second paper of the year. This one explores the molecular mechanism of TTP, a key post-transcriptional regulator of AU-rich mRNAs. Work led and coordinated by @filippekovic.bsky.social, in collaboration with Perry Blackshear.

www.nature.com/articles/s41...

13.08.2025 17:32 πŸ‘ 44 πŸ” 9 πŸ’¬ 3 πŸ“Œ 1
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CRISPR-GPT for agentic automation of gene-editing experiments - Nature Biomedical Engineering An agent-based large language model (LLM) tool helps with CRISPR-based gene-editing experimental design and analysis.

Le Cong, one of the pioneers of applying #CRISPR in eukaryotic cells, and his team now have developed an agent to apply #ChatGPT #LLM technology to automate and enhance CRISPR-based gene-editing design and data analysis.
In #nature Biomedical Engineering.
www.nature.com/articles/s41...

08.08.2025 07:15 πŸ‘ 9 πŸ” 7 πŸ’¬ 0 πŸ“Œ 0
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πŸ“πŸ€³ Become an event reporter! In exchange for a fee waiver you'll need to post social media updates from the conference and write a report summarising the meeting πŸ“·βœπŸ»

βœ… All on-site and virtual conferences at EMBL Heidelberg

Find out more and apply πŸ‘‰πŸ» https://s.embl.org/reporter

@embl.org

19.06.2025 07:33 πŸ‘ 5 πŸ” 2 πŸ’¬ 0 πŸ“Œ 0

If you are interested in pursuing a postdoc combining proteomics a genomics with functional molecular biology to study ubiquitin (-like) signaling in genome biology we are looking for candidates for the next MSCA Fellowships call!!!!

04.06.2025 21:01 πŸ‘ 5 πŸ” 9 πŸ’¬ 0 πŸ“Œ 0
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Why we love it at the Vienna BioCenter–hear it directly from our fellows!

The VIPΒ³ call is open–16 fully-funded, three-year postdoctoral fellowships in an interdisciplinary environment.

Apply now: training.vbc.ac.at/post-docs/vi...

#VBCPostDoc

@viennabiocenter.bsky.social @impvienna.bsky.social

04.06.2025 08:18 πŸ‘ 18 πŸ” 8 πŸ’¬ 0 πŸ“Œ 0
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EVE Meeting Expression of Interest

I'm thinking of organising a meeting on endogenous viral elements (RNA, DNA and retroviral) - if you'd potentially be interested, please fill out the form here - forms.gle/wrCiWMw4yXZe... - so I can gauge interest. Please RT or share with anyone maybe interested! πŸ§ͺ🧬πŸ–₯️🦠 #virology #bioinformatics

27.05.2025 11:53 πŸ‘ 14 πŸ” 21 πŸ’¬ 1 πŸ“Œ 3
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Wanted to join #EMBLRBP but couldn't?

πŸ‘©β€πŸ”¬ πŸ“· Get first-hand insights from our event reporter @ayushirehman.bsky.social here ➑️ www.embl.org/about/info/c...

#lifesciencetraining #RBPs

14.05.2025 07:36 πŸ‘ 3 πŸ” 2 πŸ’¬ 1 πŸ“Œ 0
Welcome to TomoGuide A step-by-step Cryo-ET guide

Hey #TeamTomo,
Ever been in need of a tutorial about the fundamentals of cryo-electron tomography? From preprocessing raw frames to high-res subtomogram averaging?
That's why @florentwaltz.bsky.social and I made this website!

tomoguide.github.io

Follow the thread 1 /🧡
#CryoET #CryoEM πŸ”¬πŸ§ͺ

06.05.2025 16:26 πŸ‘ 116 πŸ” 41 πŸ’¬ 5 πŸ“Œ 7

Check out this fun preview of my postdoctoral work! It highlights our findings plus lots of intriguing questions that I’m super excited to tackle in the coming years. (And the model is beautiful! Thank you! πŸ§‘β€πŸŽ¨ )

18.04.2025 18:19 πŸ‘ 20 πŸ” 6 πŸ’¬ 1 πŸ“Œ 0
The PUF RNA-binding protein, FBF-2, maintains stem cells without binding to RNA A monthly journal publishing high-quality, peer-reviewed research on all topics related to RNA and its metabolism in all organisms

Happy to see this work published in RNA, and thanks to the editors for the interview/Meet the First Author Feature! Surprisingly, we found that mutating an RNA binding protein's ability to bind RNA did not remove all biological function. #RNAsky #RNAbiology.

rnajournal.cshlp.org/content/31/5...

16.04.2025 15:19 πŸ‘ 6 πŸ” 2 πŸ’¬ 0 πŸ“Œ 0
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Excited to share our preprint on the molecular architecture of heterochromatin in human cells πŸ§¬πŸ”¬w/ @jpkreysing.bsky.social, @johannesbetz.bsky.social,
@marinalusic.bsky.social, TuroňovÑ lab, @hummerlab.bsky.social @becklab.bsky.social @mpibp.bsky.social

πŸ”— Preprint here tinyurl.com/3a74uanv

11.04.2025 08:35 πŸ‘ 360 πŸ” 141 πŸ’¬ 12 πŸ“Œ 20
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A nearly 9 year effort to design and implement new CLIP-based technologies to define multimeric protein assemblies on RNA.

Enables β€˜watching’ of RNP assemblies inside living cells

Special congrats to Luca Ducoli, Brian Zarnegar, and Paul Khavari @nature.com
www.nature.com/articles/s41...

26.03.2025 17:40 πŸ‘ 156 πŸ” 58 πŸ’¬ 3 πŸ“Œ 0
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Check out our preprint at BioRxiv revealing mechanisms of mRNP assembly during translation repression: (www.biorxiv.org/content/10.1...). Great collaboration with Olivier Duss (@olivierduss.bsky.social). Great Work Marco Payr (@marcopayr.bsky.social) and thanks for the video, explaining our paper.

11.04.2025 04:35 πŸ‘ 36 πŸ” 14 πŸ’¬ 9 πŸ“Œ 1
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A sneak peek into my experience at #EMBLRBP
Grateful for all the wonderful people I got to interact with ❀️ @events.embl.org @sloanmegan.bsky.social @shikhas.bsky.social
www.embl.org/about/info/c...

10.04.2025 13:20 πŸ‘ 7 πŸ” 1 πŸ’¬ 2 πŸ“Œ 0
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An RNA condensate model for the origin of life The RNA World hypothesis predicts that self-replicating RNAs evolved before DNA genomes and coded proteins. Despite widespread support for the RNA Wor…

An interesting perspective and framework: #RNA condensates-not individual RNAs-may have acted as replicative units in early life. RNAs in condensate recruit similar RNAs, then the condensate divides once it reaches a critical size.

#RNAsky

10.04.2025 00:28 πŸ‘ 21 πŸ” 10 πŸ’¬ 0 πŸ“Œ 1
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Next Thursday we are hosting a virtual RNA Club with Adam Cawte and Isaia Berbieri! Please join us for some cool RNA talks 😎🧬 Checkout our other threads for a little sneak preview πŸ‘€ Thank you to our sponsors @rnasociety.bsky.social and Lexogen !

03.04.2025 10:12 πŸ‘ 3 πŸ” 1 πŸ’¬ 0 πŸ“Œ 0
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DGCR8 haploinsufficiency leads to primate-specific RNA dysregulation and pluripotency defects Abstract. The 22q11.2 deletion syndrome (22qDS) is a human disorder where the majority of clinical manifestations originate during embryonic development. 2

Our latest paper is out in NAR! πŸ₯³
In collaboration with @saramaciasrna.bsky.social, we show DGCR8 haploinsufficiency disrupts pluripotency in hESC by affecting primate-specific miRNAs and TEs. Our findings highlight a co-evolved miRNA-TE network in primates.
Read:
academic.oup.com/nar/article-...

27.03.2025 10:13 πŸ‘ 29 πŸ” 13 πŸ’¬ 1 πŸ“Œ 2
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Widespread variation in molecular interactions and regulatory properties among transcription factor isoforms @fuxmanlab.bsky.social
www.cell.com/molecular-ce...

27.03.2025 04:30 πŸ‘ 4 πŸ” 2 πŸ’¬ 0 πŸ“Œ 0
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Add your preprint to the Biologists @ 100 preList The preLights conference reporter for Biologists @100, Jonathan Townson, is collating a preList that aims to capture all preprints being discussed at the meeting (either as part of the poster sessions...

I’m also curating a preList with @prelights.bsky.social, so if you’re coming along to present a preprint then please send it in here: forms.gle/JYiTFj8iSUcT... (2/2)

24.03.2025 09:07 πŸ‘ 3 πŸ” 3 πŸ’¬ 0 πŸ“Œ 0

Two updates with this project! First, this work is now published here: academic.oup.com/nar/article/...

Second, our software for identifying 8-oxoguanosine via RNAseq, PIGPEN, is now installable via bioconda: anaconda.org/bioconda/pig...

21.03.2025 15:25 πŸ‘ 30 πŸ” 9 πŸ’¬ 2 πŸ“Œ 0

Our genome encodes > 7000 microproteins that have been previously ignored in genome annotations. How do these microproteins impact tissue function? Here, we use an in vivo single-cell CRISPR screen to systematically explore microprotein function in the mouse epidermis. 1/9

19.03.2025 15:44 πŸ‘ 66 πŸ” 17 πŸ’¬ 3 πŸ“Œ 5
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Calling #Drosophila #grad students #postdoc and #pretenure #faculty to participate in FlyCROSS and be matched by a #mentor of your preferences to gain guidance to your unique needs !
#genetics #dros25 #phdlife

@flybase.bsky.social @bdsc.bsky.social

06.12.2024 16:37 πŸ‘ 30 πŸ” 41 πŸ’¬ 2 πŸ“Œ 2

Looking for candidates for the FI STEP PhD fellowship. Deadline 31/03. Contact me if you are interested in joining the lab to develop your PhD project. agaur.gencat.cat/en/beques-i-...

19.03.2025 16:09 πŸ‘ 2 πŸ” 3 πŸ’¬ 0 πŸ“Œ 0
Schematic of potential complexes that form between TAM receptors and apoptosis cells or viruses at the cell surface

Schematic of potential complexes that form between TAM receptors and apoptosis cells or viruses at the cell surface

Our lab is excited to hire a postdoctoral researcher to study the mechanisms that viruses use to β€˜hijack’ TAM receptors in viral spread. We are looking for someone who is excited to learn new techniques and work in a highly collaborative team! Please share!

unc.peopleadmin.com/postings/298...

18.03.2025 14:59 πŸ‘ 69 πŸ” 45 πŸ’¬ 1 πŸ“Œ 5