(continued) on the same Mr A, we compare people like Mr A receiving X and another group of people like Mr A not receiving X. So a between-person comparison. There is no conflict whatsoever between the two.
This was a most illogical contrast one could ask. A clinician treats Mr A, and is interested in how they change over time. So a within-person change. But in deciding how to treat Mr A, the clinician must contrast Mr A receiving treatment X and not receiving it. Because we cannot do this (continue)
Itβs just another completely wrong use of the term statistical significant, donβt you think?
Very probably neither the reviewers or editors understood this.
I think they are even worse than that. They showed that sex is a prognostic factor. But they don't understand that prognostic factors essentially have no place in precision psychiatry. Precision psychiatry is about treatment*covariate interactions, i.e. about effect modifiers or HTE.
Bar graphs show smallest worthwhile difference distributions for atherosclerotic cardiovascular disease risk in the US & Japan. Baseline risks are 2%, 10%, & 20%. X-axis: SWD in absolute risk reduction from baseline. Y-axis: percentage of US/Japanese participants.
Most statin-eligible adults in the US and Japan desire greater absolute risk reduction than current statin efficacy provides before initiating therapy for #ASCVD prevention.
ja.ma/4kDy02Y
Editorial titled, "Statins for Primary PreventionβThe Gap Between Guidelines and Patient Preferences" by Ilana B. Richman et al. Text discusses when to use statins for preventing atherosclerotic cardiovascular disease (ASCVD).
π¬ Editorial: Statin guidelines and patient preferences for #ASCVD prevention often misalign, supporting the need for clearer risk communication and shared decision-making in clinical practice.
ja.ma/4rKRFAo
The editorial concluded: "Findings from the study by Luo et al4 support a call for renewed efforts to engage in shared decision-making with patients when discussing primary prevention of cardiovascular disease. ... understanding and honoring patientsβ preferences
will remain essential."
The SWD was defined as the smallest reduction in the absolute risk of cardiovascular events at which participants would consider initiating statins given potential adverse events and burden of associated costs
and health care visits. jamanetwork.com/journals/jam...
Today we published a survey of the SWD (smallest worthwhile difference) of statins, which found that the median SWDs exceeded its actual efficacy across all risk scenarios, suggesting that laypeople demand greater benefits than statins typically provide. jamanetwork.com/journals/jam...
In the shortest, use SMD, supplemented by CER/EER (control event rate & experimental event rate) for interpretability. mentalhealth.bmj.com/content/27/1...
Is this SMD or MD?
Indeed, who with a sane/scientific mind can claim an effect size > 1.0? The readers, and the authors, should think twice.
Perhaps an article of interest from our team: J Clin Epidemiol, 2022 vol. 150 pp. 90-97
Retracted randomized controlled trials were cited and not corrected in systematic reviews and clinical practice guidelines.
www.ncbi.nlm.nih.gov/pubmed/35779...
A Taylor & Francis journal has retracted a widely-read paper linking cardiac-related mortality to COVID-19 vaccines after an unsuccessful legal attempt by the lead author to block the withdrawal. That author says he is considering further legal action against the publisher.
Relaxation was found, once again and again, to be harmful.
www.sciencedirect.com/science/arti... as in acute treatment www.thelancet.com/journals/lan..., as in insomnia treatment jamanetwork.com/journals/jam..., as in panic disorder www.cambridge.org/core/journal..., and a few more coming.
Component NMA of depression prevention trials find that efficacious interventions can include problem-solving and behavioral activation. www.sciencedirect.com/science/arti...
Congratulations and thank-you, @ploederl.bsky.social. It is unfortunate that we need more of these but it is the sad state of affairs in the current science publications.
Davos starts today. But itβs been seven years since Rutger Bregman said everything that needed sayingβ¦ and the rich and powerful are still pretending like they havenβt heard a thing.
Last call for abstracts! Present your research at the WCCBT World Congress alongside 25+ keynote presentations. Register now, submit to the Call for Abstracts and be part of the future of #CBT. See you in San Francisco! wccbt2026.org
#WorldCongress26 #SanFrancisco #WCCBT #ABCT
This is no joke. This is exactly what we might see in 10 years or in 20 years.
Funding Justice for Two Deported American Activists
NIF is funding the legal appeal for two American Jewish women who were detained, deported, and banned from the country after working with Palestinian farmers. γwww.nif.org/stories/huma...
Facing Down Intimidation in Ben Gurion Airport
Zak Witus, NIFβs Director of Young Leadership and Education, reflects on the experience of being detained in Ben Gurion airport in a piece published in the Forward.γforward.com/opinion/7870...
I am not too sure of that, Ioana. There are two potential problems here. First the questionable validity of the autism diagnosis. No AI can fix that, probably. Two this questionable diagnosis is sloppily applied in the real world. Maybe the ML algorithm can rectify this to a certain degree.
Once you learn the CBT skills with the Resilience Training App, you can remain healthier --- a sign of true resilience and true learning taking place!
