Joao P. De Aquino, M.D.'s Avatar

Joao P. De Aquino, M.D.

@jpdeaquinomd

Assistant Professor of Psychiatry at Yale | 🧠 mechanisms of pain and reward | neuropsychopharmacology | developing novel therapeutics for pain and addiction https://medicine.yale.edu/lab/pain/

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13.02.2025
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Latest posts by Joao P. De Aquino, M.D. @jpdeaquinomd

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Excited to share that I’ve received the 2026 Young Investigator Award from the International Narcotics Research Conference (INRC). Grateful to Dr. Anne Murphy for the nomination. Looking forward to presenting our lab’s work on #pain, #opioids, and #addiction in Denver this July.

07.03.2026 22:21 πŸ‘ 0 πŸ” 0 πŸ’¬ 0 πŸ“Œ 0
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Modulating the endocannabinoid system in alcohol use disorder: A translational systematic review and meta-analysis of preclinical and human studies - Molecular Psychiatry Molecular Psychiatry - Modulating the endocannabinoid system in alcohol use disorder: A translational systematic review and meta-analysis of preclinical and human studies

New paper out in Molecular Psychiatry on the endocannabinoid system in alcohol use disorder.

Really proud of our team for conducing this large translational review and meta-analysis (63 studies).

Strong preclinical signal, but a clear translational gap in humans. We outline what needs to change.

27.02.2026 14:05 πŸ‘ 0 πŸ” 0 πŸ’¬ 0 πŸ“Œ 0
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Honored to join Drug and Alcohol Dependence as Associate Editorβ€”the flagship journal of the College on Problems of Drug Dependence (CPDD).

Excited to support rigorous, constructive peer review in #addiction #science. Grateful to the editorial leadership!

www.sciencedirect.com/journal/drug...

29.01.2026 21:52 πŸ‘ 2 πŸ” 0 πŸ’¬ 0 πŸ“Œ 0
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Exploring the effects of cannabidiol on pain sensitivity using quantitative sensory testing among individuals receiving methadone or buprenorphine for opioid use disorder: an open-label, proof-of-conc... While medications for opioid use disorder (MOUD) effectively treat opioid use disorder (OUD), concurrent pain management remains challenging. Cannabid…

Can #cannabidiol (CBD) help #pain in people with #OpioidUseDisorder? Our proof-concept study suggests CBD may modulate pain differently depending on whether people are on #methadone or #buprenorphine, with promising signals at lower doses and good tolerability.

shorturl.at/jlB7V

16.12.2025 00:52 πŸ‘ 0 πŸ” 0 πŸ’¬ 0 πŸ“Œ 0
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🎀 Call for Symposia Proposals topics related to clinical practice, basic science or mechanisms, and translational research related to pain. Ideally, presentations include multiple disciplines.

The deadline to submit proposals is October 15, 2025

15.10.2025 18:16 πŸ‘ 6 πŸ” 4 πŸ’¬ 0 πŸ“Œ 0

We are now accepting applications for the third annual USASP Leadership Academy (LA), which aims to develop the next generation of leaders in the pain field. We aim to recruit pain scholars with high potential to accelerate the development of leaders in pain research, practice, policy, and education

27.09.2025 00:34 πŸ‘ 1 πŸ” 1 πŸ’¬ 1 πŸ“Œ 0
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Join us in Congratulating the 2025 ACNP Travel Award Class! πŸ™ŒπŸŽ‰

08.08.2025 13:00 πŸ‘ 38 πŸ” 11 πŸ’¬ 0 πŸ“Œ 8
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Applying psychophysiological measures during an emotion reappraisal task, we show that emotion regulation capacity predicts #Cannabis use frequency more than #Pain severity among #ChronicPain patients on long-term #Opioid therapy.

shorturl.at/pQUf7

07.08.2025 18:46 πŸ‘ 0 πŸ” 0 πŸ’¬ 0 πŸ“Œ 0
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The Role of Childhood Trauma in Chronic Pain and Substance... : Journal of Addiction Medicine and substance use compared with those without such history. Methods: We conducted a cross-sectional study of 82 individuals receiving methadone for OUD. Participants completed the Childhood Trauma ...

Thrilled to share our new Journal of #Addiction Medicine paper!

We found that childhood #trauma correlates with worse #pain, higher #alcohol use & earlier #cannabis initiation, highlighting the need for trauma‑informed care in #OpioidUseDisorder treatment. πŸ‘‡

shorturl.at/2KXa2

30.07.2025 14:36 πŸ‘ 0 πŸ” 0 πŸ’¬ 0 πŸ“Œ 0
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Pain interference, alcohol use, and metabolic health: Insights from a nationally representative study This nationwide study found that heavy alcohol consumption and obesity each magnify the impact of chronic pain on daily lifeβ€”by approximately 34% and 50%, respectivelyβ€”and that their effects are addi...

Pain, addiction, and metabolism are fundamentally intertwined.

Our new work in @acerjournal.bsky.social quantifies how heavy #drinking and #obesity additively worsen #pain, while each extra hour of #sleep and higher physical activity are protective.

onlinelibrary.wiley.com/doi/10.1111/...

26.06.2025 14:26 πŸ‘ 1 πŸ” 0 πŸ’¬ 0 πŸ“Œ 0