Farzin Hajebrahimi's Avatar

Farzin Hajebrahimi

@farzinha

Enthusiastic about β€œhow” 🧠 works. BME Postdoc @NJIT

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06.10.2023
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Latest posts by Farzin Hajebrahimi @farzinha

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Distributed cortical network dynamics of binocular convergent eye movements in humans Abstract. Neuroimaging studies in humans have localized brain functions to specific brain regions, but a recent shift toward distributed network-based models of brain function promises deeper insights...

A huge thank you to my incredible mentors, Tara Alvarez and @mwcole.bsky.social, for their invaluable support on this work! Please read the full paper here: doi.org/10.1162/NETN...
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25.02.2026 19:53 πŸ‘ 1 πŸ” 0 πŸ’¬ 0 πŸ“Œ 0

Understanding these distributed pathways provides a new lens for clinical conditions like concussion-related oculomotor dysfunction. It’s not just about one damaged region; it’s about how the whole network communicates. 7/8

25.02.2026 19:53 πŸ‘ 0 πŸ” 0 πŸ’¬ 1 πŸ“Œ 0

By testing participants across separate scanning sessions, we found that these network signatures are stable. The brain's intrinsic architecture for convergent eye movements is a robust blueprint that reliably supports functional responses. 6/8

25.02.2026 19:53 πŸ‘ 0 πŸ” 0 πŸ’¬ 1 πŸ“Œ 0
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The Heavy Lifters: VIS and DAN πŸ‹οΈ Which networks drive this flow? Our results showed that the Visual and Dorsal Attention networks dominate the propagation of signals during convergent eye movements. 5/8

25.02.2026 19:53 πŸ‘ 0 πŸ” 0 πŸ’¬ 1 πŸ“Œ 0
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We focused on the Cortical Circuitry of Convergence, including the primary visual cortex and frontal/parietal and supplementary eye fields. When we excluded these core regions from the model's "source," the rest of the brain's network connectivity accurately regenerated their activity. 4/8

25.02.2026 19:53 πŸ‘ 0 πŸ” 0 πŸ’¬ 1 πŸ“Œ 0
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We used Activity Flow Mapping to model how task activations arise from the propagation of activity across distributed connectivity pathways and showed that activity-flow-generated activation patterns closely match the actual task activations during convergent eye movements. 3/8

25.02.2026 19:53 πŸ‘ 0 πŸ” 0 πŸ’¬ 1 πŸ“Œ 0

Coordinated activity across both eyes is essential for maintaining single visual perception, supporting everyday activities such as reading and interacting with digital screens. Impairments in this system can result in significant functional limitations, also seen in neurological disorders. 2/8

25.02.2026 19:53 πŸ‘ 0 πŸ” 0 πŸ’¬ 1 πŸ“Œ 0

Our recent study, "Distributed cortical network dynamics of binocular convergent eye movements in humans" is out in Network Neuroscience, where we move beyond simple brain mapping to show that binocular convergence is driven by the flow of activity across distributed neural networks. 1/8

25.02.2026 19:53 πŸ‘ 4 πŸ” 1 πŸ’¬ 1 πŸ“Œ 0
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Characteristics and mechanisms of cognitive impairment in Parkinson disease Nature Reviews Neurology, Published online: 03 December 2025; doi:10.1038/s41582-025-01163-xCognitive impairment is one of a range of non-motor symptoms that people with Parkinson disease (PD) can experience in addition to the hallmark motor symptoms of the disease. In this Review, Oikonomou et al. outline the epidemiology and natural history of cognitive decline in PD and related disorders, and discuss the key underlying pathophysiological factors and mechanisms.

New online! Characteristics and mechanisms of cognitive impairment in Parkinson disease

04.12.2025 09:10 πŸ‘ 3 πŸ” 2 πŸ’¬ 0 πŸ“Œ 0
Schematic depicting cortical-subcortical interactions during multi-task learning

Schematic depicting cortical-subcortical interactions during multi-task learning

Excited to see our paper with @mwcole.bsky.social finally out in peer-reviewed form @natcomms.nature.com! We examine how the human brain learns new tasks and optimizes representations over practice…1/n

19.11.2025 18:03 πŸ‘ 24 πŸ” 7 πŸ’¬ 1 πŸ“Œ 0
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Lab’s latest is out in Imaging Neuroscience, led by Kirsten Peterson: β€œRegularized partial correlation provides reliable functional connectivity estimates while correcting for widespread confounding”, where we demonstrate a major improvement to standard fMRI functional connectivity (correlation) 1/n

14.09.2025 21:34 πŸ‘ 75 πŸ” 30 πŸ’¬ 6 πŸ“Œ 0

Stories no one had heard in years…

21.12.2024 16:28 πŸ‘ 2 πŸ” 0 πŸ’¬ 0 πŸ“Œ 0
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β€œCognitive flexibility as the shifting of brain network flows by flexible neural representations”, a solo paper by yours truly, making the case that brain activity flow shifts are essential to mental flexibility (and quite interesting too!)

Open access: www.sciencedirect.com/science/arti...

03.12.2024 18:12 πŸ‘ 103 πŸ” 27 πŸ’¬ 2 πŸ“Œ 0
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Distributed network flows generate localized category selectivity in human visual cortex Author summary A fundamental question in neuroscience has persisted for over a century: to what extent do distributed processes drive brain function? The existence of category-selective regions within...

Lab’s latest at PLOS Comp Biol, led by Carrisa Cocuzza: β€œDistributed network flows generate localized category selectivity in human visual cortex”. This one changed how I think the brain works! Even "localized" functions are likely generated by distributed processes doi.org/10.1371/jour...

05.11.2024 01:33 πŸ‘ 17 πŸ” 12 πŸ’¬ 0 πŸ“Œ 1