Effects of daily multivitamin–multimineral and cocoa extract supplementation on epigenetic aging clocks in the COSMOS randomized clinical trial
www.nature.com/articles/s41...
Stem Cell Therapy Improved Condition of Patients with Age-Related Frailty
www.cell.com/cell-stem-ce...
A brief, 16-h fasting regimen can enhance immunotherapy efficacy in both mice and humans.
www.sciencedirect.com/science/arti...
‘Lipstick on a pig’: how to fight back against a peer-review bully
Scientific societies, journals, editors and researchers are pushing back against mean-spirited peer reviews.
www.dementiaresearcher.nihr.ac.uk/how-to-fight...
This study reveals a non-metabolic function of the metabolite pyruvate, and provides insights into how high glucose impairs IFN-I antiviral immunity through pyruvate, offering strategies to improve IFN-I immune activity for both preventing and treating viral infections.
Pyruvate is a natural suppressor of interferon signaling by inducing STAT1 protein pyruvylation
www.sciencedirect.com/science/arti...
Dear Stephen, is it possible to invite you to write a commentary article reflecting on the findings of this paper?
Call for Youth Editorial Board Members
Please send your CV to:
Nutrition@the-innovation.org
NO APC, Publish Faster, Reach Further. Join The Innovation Nutrition (TIN) global community!
Publish Faster, Reach Further, No APC!Join The Innovation Nutrition (TIN) global community!
Nutrient allocation fuels T cell-mediated immunity
www.cell.com/cell-metabol...
The human gut microbiota has rapidly changed during dietary urbanization. However, the human genome cannot change substantially over one generation, leaving it potentially ill-equipped to adapt to evolving microbial functions associated with rising non-communicable diseases (NCDs).
A modified prolactin-releasing peptide, NN501, with agonist properties at both GPR10 and neuropeptide FF receptor 2 (NPFFR2) causes significant weight loss without apparent side effects and with slower weight gain after cessation.
www.cell.com/cell-metabol...
The quest to slow aging leads scientists into the powerhouse of cells
www.washingtonpost.com/science/2025...
What to Know About the New Blood Pressure Guidelines
"The guideline does note that reducing alcohol intake appears to have bigger BP reduction benefits for people who drink more, regardless of whether they have hypertension."
jamanetwork.com/journals/jam...
Cardiometabolic parameter change by weight regain on tirzepatide withdrawal in adults with obesity
jamanetwork.com/journals/jam...
Metformin Blunts Vascular Insulin Sensitivity After Exercise Training in Adults at Risk for Metabolic Syndrome
academic.oup.com/jcem/advance...
Egg intake and cognitive function in healthy adults: A systematic review of the literature
Moderate whole egg consumption may be associated with improvements in cognitive outcomes in healthy adults, including reduced dementia risk and better memory performance
www.sciencedirect.com/science/arti...
Today, medical research builds up an understanding of the whole from molecular parts, but artificial intelligence can revive an approach building down from patient-level data to theory and understanding.
Fish Oil for Patients Receiving Hemodialysis — Red Herring or Great Catch?
www.nejm.org/doi/full/10....
Yang et al. developed a self-adaptive fine-tuning method that dynamically adjusts the parameters of the models to minimize the loss function, which includes direct quantification of artifacts from live-cell imaging.
doi.org/10.1016/j.xi...
#deeplearning #microscopy #adaptiveimaging
This study shows that M31 UCXB-1 is a BH-WD system, with the shortest orbital period, the possibly strongest gravitational wave emission, and the most massive white dwarf among the known UCXBs.
doi.org/10.1016/j.xi...
#astrophysics #blackholes #GravitationalWaves #whitedwarfstars
Deng et al. analyzed an expanded genetic dataset comprising #systemiclupuserythematosus (SLE) with pulmonary arterial hypertension (PAH), SLE without PAH (SLE-nonPAH), and healthy control cohorts, identifying rare TRAF5 coding variants associated with SLE-PAH.
doi.org/10.1016/j.xi...
#genetics
Check out the latest issue of The Innovation Medicine!!!
Volume 2, Issue 4 is now online! @innovationmedicine.bsky.social
www.the-innovation.org/medicine/art...
#medicine #biomedical #Cancer #immunotherapy #cadiovascular #type2diabetes #hypertension #ArtificialIntelligence #clinical #research
Follow @topscience.bsky.social for daily updates! 🥂💐
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Microplastic exposure linked to accelerated aging and impaired adipogenesis in fat cells
"The multifaceted impact of microplastic exposure on adipose tissue: its role in inducing cellular senescence, amplifying inflammatory responses, and impairing differentiation capacity"
doi.org/10.1038/s415...
The complete telomere-to-telomere sequence of a mouse genome. @science.org
"This work allows for the characterization of ribosomal DNA, as well as previously uncharacterized genes, and will provide an important resource to researchers working in mouse genetics."
www.science.org/doi/10.1126/...
A new way to create realistic 3D shapes using generative AI. #MIT
Researchers propose a simple fix to an existing technique that could help artists, designers, and engineers create better 3D models.
Read more
news.mit.edu/2024/creatin...
Paper:
arxiv.org/pdf/2405.15891
Academic Journals and News
(Updated Dec 3, 2024)
go.bsky.app/hCfhqn
In case some mentors may want to read this. #Nature #PhD #scisky #student #mentor
Source:
www.researchgate.net/publication/...
How to write an excellent Review article @natrevbioeng.bsky.social #scisky #Science #REVIEW
Open Access
www.nature.com/articles/s44...
