Patrik Rödin Mörch

Alt EN: Colorful collage of diverse amphibians including frogs, salamanders, newts, caecilians, and an axolotl arranged on a black background. Text on image: "Why sequence amphibian genomes?" Alt ES: Collage colorido de diversos anfibios incluyendo ranas, salamandras, tritones, cecilias y un ajolote sobre un fondo negro. Texto en la imagen: "¿Por qué secuenciar los genomas de los anfibios?"

Alt EN: A tiny brown frog perched on a person’s fingertip, highlighting its small size and delicate features. Text on image: "More than 40% of amphibian species are at risk of extinction. Genomes help identify genetic vulnerability, resilience, and adaptive potential for targeted conservation." Alt ES: Una pequeña rana marrón posada sobre la yema del dedo de una persona, destacando su diminuto tamaño y fragilidad. Texto en la imagen: "Más del 40% de las especies de anfibios están en riesgo de extinción. Los genomas ayudan a identificar vulnerabilidad genética, resiliencia y potencial adaptativo para una conservación dirigida."

🌍✨ Why sequence amphibian genomes?
🚨 More than 40% of amphibian species are at risk of extinction.
🧬 Their genomes reveal vulnerability, resilience, and adaptive potential — helping conservation act before populations are lost.
🐸 Proteger a los anfibios es proteger el futuro de la biodiversidad. 💻🧬

Why genome sequence nudibranchs? 🌈🧬
Because these vibrant sea slugs hide some of the ocean’s most extraordinary biological tricks.
From toxin evolution and chemical defenses 🧪 to symbioses, pigmentation, and extreme metabolic adaptations, nudibranch genomes reveal how life innovates in the sea. 🌊

Excited to share our final accepted version of the CiFi method out today: www.nature.com/articles/s41...

One month later and those 30 billion base pairs are crammed into just about 14 chromosomes. HOT DANG! This seemed impossible 4-5 years ago.

Just over a month left to apply for scholarships on this project. We will run internal pre-selection interviews end of November, so if you consider applying, please reach out now. I can guarantee amazing scientific and intellectual environment at the Institute for Eco Evo @edinburghup.bsky.social

I am thrilled to share this paper outlining some ideas I’ve been thinking about for a little while on a simple but powerful approach for predicting risk of inbreeding depression from long runs of homozygosity and non-ROH heterozygosity. 1/n @klohmueller.bsky.social doi.org/10.1016/j.tr...

Genome engineering in biodiversity conservation and restoration - Nature Reviews Biodiversity This Perspective argues for the use of genome engineering for restoring species genetic diversity and increase species resilience to environmental change. Genome engineering could be combined with tra...

Happy to share that our Perspective on how genome editing could restore lost diversity and help species adapt to climate or disease is out in @natrevbiodiv.nature.com
We discuss potential, unknowns and risks
tinyurl.com/33nm48vd
Free access here: rdcu.be/ewMBq
#consgen #popgen #Biodiversity

Super excited for this chance to share our @biorxivpreprint.bsky.social #preprint, in wihch we ask a simple question – what were the genomic of gorillas evolving polygyny?

www.biorxiv.org/content/10.1...

(1/2) 🦋 The Atlas Blue butterfly has a staggering 229 chromosomes—far beyond the usual 31–32 in most moths and butterflies! 🧬
Join EBP trailblazer Mark Blaxter and the @sangerinstitute.bsky.social team as they tackle the challenge of assembling them all.
👉learn more: bit.ly/3TIXLSU
📸 M. Harzallah

Biodiversity Genomics Research Practices Require Harmonising to Meet Stakeholder Needs in Conservation Biodiversity resilience relies on genetic diversity, which sustains the evolutionary potential of organisms in dynamic ecosystems. Genomics is a powerful tool for accurately estimating genetic divers...

📢 It’s time to harmonise practices for assessing genome-wide genetic diversity 🧬 Standardisation is key to meet the needs of stakeholders in biodiversity #conservation.
🔗 New publication by #ERGA
@biogeneurope.bsky.social out now in #MolecularEcology
onlinelibrary.wiley.com/doi/10.1111/...

Only two more days to apply!! Put your name in the hat, even if you feel like you don't match all criteria listed. Happy to chat regardless!

Cell Press: STAR Protocols STAR Protocols is an open access, peer-reviewed journal from Cell Press. We offer structured, transparent, accessible, and repeatable step-by-step experimental and computational protocols from all are...

Interested in measuring genetic load? We have a new paper out providing a modified version of GERP which is more user friendly in wildlife species and with scripts to automate making input files and pulling out derived alleles in your species #consgen #popgen star-protocols.cell.com/protocols/4202

Repeatability of evolution and genomic predictions of temperature adaptation in seed beetles - Nature Ecology & Evolution The authors compare genomic and phenotypic changes between genetic backgrounds of seed beetles evolved at hot or cold temperatures. Despite phenotypic changes being more rapid and predictable at hot t...

Finally out: Predicting adaptation to climate warming www.nature.com/articles/s41...

We find that there are many genomic routes to heat-adaptation, but this can also make genomic data of limited value for prediction. A tour de force by @denovorego.bsky.social , with @stelkens.bsky.social.

How to clone a Dire Wolf? | EMBO reports EMBO Press is an editorially independent publishing platform for the development of EMBO scientific publications.

www.embopress.org/doi/full/10....

Struggling to find the tiny microchromosomes in draft bird genome assemblies?

Our new #preprint introducing MicroFinder can help: www.biorxiv.org/content/10.1...

🧵 below

(1/n)

@sangerinstitute.bsky.social

Ngorongoro Crater Lion. Photo: I. Jansson

demography

pop. gen. indices

Great to see our latest paper on Ngorongoro Crater lion genomics out @commsbio.bsky.social

Even after a rapid post-epizootic recovery in the 1970s, habitat fragmentation and continued isolation led to an increase in genetic load and to a reduction in overall genetic variation.

🚨 New preprint!
We analyzed 39 bird genomes—including 3 Mauritian species that bounced back from the brink of extinction—to explore genomic erosion in a comparative framework.
🧬🦜🧩
📄 www.biorxiv.org/content/10.1...
#consgen #popgen
@claudiafontsere.bsky.social

Cover: Northern brown argus (Aricia artaxerxes) mating in the wild in Uppland, Sweden. These individuals (female-left, male-right) and forty of their offspring were later whole-genome resequenced to make a linkage map. Boman J., Nolan, Z.J. And Backström, N. On the origin of an insular hybrid butterfly lineage. Evolution 79 (4)

I feel honored that our work: "On the origin of an insular hybrid butterfly lineage" was picked as "Editor's choice" and that my picture of a mating couple (🧡🤎) covers the latest issue of Evolution @journal-evo.bsky.social. Link to paper: academic.oup.com/evolut/artic... (1/8)

📢 NEW GENOME ALERT

In #G3journal, Rödin-Mörch et al. generated a high-quality reference genome of the European green toad to understand the evolutionary genomics of the amphibian.

Read more: buff.ly/XnaKB29

PhD Student in Evolution of Seasonal Camouflage The Department of Zoology at Stockholm University includes about 80 employeese, including Researchers, PhD students and administrative staff. Research and education at the department occurs in an inte

PhD position on Evolution of Seasonal Camouflage in my group. Fully funded 4 year position in Stockholm University and SciLifeLab! :-)

su.varbi.com/en/what:job/...

The orange-bellied parrot is predicted to go extinct by 2038. We tracked >200 years of genomic erosion. Here’s what we found 🧬🦜 #ConservationGenomics #consgen #popgen
onlinelibrary.wiley.com/doi/10.1111/...
pic by Marc Gardner

🧬🌍 Happy to see our latest paper out at @royalsocietypublishing.org
We show how genetic risks in endangered species can stay hidden due to a time-lag between demographic collapse and genetic loss. Work led by amazing MSc students Xufen Liu and Ester Milesi #ConservationGenomics
Pic by David Stowe

Dental calculus, the preserved oral microbiome, is an absolute treasure trove of information that can be interrogated across thousands of years. But how to make it work? In a new preprint, @markella-morait.bsky.social asks this questions using >30 mammalian species:
doi.org/10.1101/2025...

Accessible, realistic genome simulation with selection using stdpopsim Selection is a fundamental evolutionary force that shapes patterns of genetic variation across species. However, simulations incorporating realistic selection along heterogeneous genomes in complex de...

stdpopsim v0.3.0 is out! You can now mix and match your simulations of different demographic histories with published distributions of fitness effects along with gene annotations, and you can even throw in sweeps for good measure. Check out the new manuscript for more info: doi.org/10.1101/2025...

BWA-0.7.19 released with a fix to the internal HD-line bug introduced in 0.7.18

Substitution load revisited: a high proportion of deaths can be selective Abstract. Haldane's Dilemma refers to the concern that the need for many “selective deaths” to complete a substitution (i.e. selective sweep) creates a spe

Our latest paper revisits Haldane 1957 on speed limits to adaptation, the paper that triggered neutral theory. We clarify and then significantly extend the theory, and apply the resulting model to @mexpositoalonso.bsky.social's data doi.org/10.1093/gene... 1/14

A chromosome-level genome assembly of the European green toad (Bufotes viridis)
Published yesterday in G3
@GeneticsGSA

A chromosome-level genome assembly of the European green toad (Bufotes viridis) Abstract. The European green toad (Bufotes viridis) is geographically widely distributed. While the species global conservation status is labeled as of lea

Here is the link:

academic.oup.com/g3journal/ar...

Postdoctoral Research Fellow in Evolutionary and Comparative Genomics (277333) | University of Oslo Job title: Postdoctoral Research Fellow in Evolutionary and Comparative Genomics (277333), Employer: University of Oslo, Deadline: Wednesday, April 9, 2025

[Please share widely]
Come work at the U. of Oslo. We are advertising a 3-year postdoc in Evolutionary and Comparative Genomics. If working with plant evolution in the Galápagos, pangenome and structural variants sounds exciting for you - this may be your chance!

www.jobbnorge.no/en/available...

UppTalk: What can primates teach us about adaptation and survival? YouTube video by Uppsala universitet

I was recently interviewed by Maia Garde for #UppTalk, the @uu.se outreach program. We talked about the spectacular work of @axeljensen.bsky.social on guenons, the true Rebel #Monkeys, and a bit about tracking mountain gorillas. Listen in if you like #primates & #genomics youtu.be/91zFERdT3oQ?...