Frank Arnold

Heterocellular crosstalk and architecture of the pancreatic tumour microenvironment Nature Reviews Cancer, Published online: 16 January 2026; doi:10.1038/s41568-025-00905-9Pancreatic ductal adenocarcinoma is defined by a fibroinflammatory microenvironment, which influences both disease progression and therapy response. In this Review, Arnold et al. outline our current understanding of the complex interplay between the stromal elements of the tumour microenvironment in pancreatic ductal adenocarcinoma and present ways we might use this knowledge to develop better therapeutic strategies for patients with pancreatic cancer.

Last week, I had the incredible chance to attend Richard Strauss’s „Die Frau ohne Schatten” #MetOpera. Special thanks to #MSKEducation and #MSKKathrynAndersonOperaFund for this amazing and unforgettable evening.