Enrique Gabandé Rodríguez

📢 Open position: Lab technician 📢 within the project PID2024-156818NB-I00 led by Dr. Rafael Medina & Dr. Elisa Carrasco, funded by @ageinves.bsky.social . Spread the word! Applications welcome

PhD students’ taste for risk mirrors their supervisors’ Learned risk-taking behaviours can persist for years after leaving the lab — and even after taking on a new research topic.

A researchers’ propensity for risky projects is passed down to their doctoral students — and stays with trainees after they leave the laboratory

go.nature.com/4sHq58H

Molecular Mechanisms of Childhood Leukemia Development - Centro de Biología Molecular Severo Ochoa Job Description We are seeking a highly motivated postdoctoral researcher to join our laboratory to study the early steps of development of childhood B-cell Acute Lymphoblastic Leukemia (B-ALL). The p...

📢¡Oferta de trabajo en el CBM!
El grupo de César Cobaleda busca postdoc para estudiar cómo se origina la leucemia infantil (B-ALL).
💡 Proyecto “la Caixa” Research Health 2025
🧬 Modelos murinos, epigenética, célula única
📅 Deadline: 5 dic 2025
www.cbm.uam.es/index.php/jo...
@cjchcm.bsky.social

🌟 Barcelona scientists, don’t miss out!
Tomorrow we host Dr. María Mittelbrunn for our plenary seminar. It is going to be a great one! @irbbarcelona.org

mmittelbrunnlab.cbm.uam.es

Nobel Laureate Professor Sir John Gurdon dies aged 92 It is with great sadness that the University shares the news of the death of Professor Sir John Gurdon, founder of the Gurdon Institute.

Sad to hear about the passing of John Gurdon, a titan and pioneer of developmental biology and much more. Winner of the Nobel Prize in Medicine or Physiology, shared with Shinya Yamanaka, who actually was inspired by his work
www.cam.ac.uk/research/new...

Review @sciimmunology.bsky.social @platten-lab.bsky.social
@dkfz.bsky.social
The immunology of brain tumors
www.science.org/doi/10.1126/...

Diabetes-induced senescence of endothelial cells shown to promote pancreatic cancer progression doi.org/10.1038/s414...

O M G

Cincuentenario del Centro Biología Molecular Severo Ochoa - Decoding life YouTube video by Centro de Biología Molecular Severo Ochoa

🎥🔬 50 años descodificando la vida.
Descubre en este video cómo el CBM ha marcado la biomedicina en España y el mundo, formando talento y generando ciencia de impacto.
#CincuentenarioCBM #DecodingLife youtu.be/7bzJOIW5kyM

Rewiring of cortical glucose metabolism fuels human brain cancer growth - Nature The cortex fuels essential physiological processes with glucose-derived carbon, while gliomas fuel their aggressiveness by rerouting glucose carbon pathways and scavenging alternative carbon sources such as environmental amino acids, providing a potential therapeutic target.

Nature research paper: Rewiring of cortical glucose metabolism fuels human brain cancer growth

go.nature.com/4lZtawb

José Antonio Marina (86 años), catedrático de filosofía: “Un amigo de verdad es el que te hace mejor. Y si no te hace mejor, no es un amigo, es otra cosa” ¿Qué significa tener un buen amigo? ¿Cuál es el verdadero valor de la amistad? ¿Y cómo deberíamos cultivar nuestras relaciones de amistad para hacerlas verdaderamente significativas? El filósofo José ...

José Antonio Marina (86 años), catedrático de filosofía: “Un amigo de verdad es el que te hace mejor. Y si no te hace mejor, no es un amigo, es otra cosa”

www.cuerpomente.com/psicologia/j...

Hematopoietic loss of Y chromosome leads to immune inhibitory receptor up-regulation, impairing senescent cell clearance
www.science.org/doi/10.1126/...

🔬Un estudio del CSIC demuestra que el deterioro asociado a la edad de los linfocitos T CD4 debilita la barrera intestinal y favorece la inflamación crónica y el envejecimiento celular

💉 El trabajo también presenta una posible terapia

➡️ https://tinyurl.com/97ssrv74

@cbm-csic-uam.bsky.social

Excessive glycosylation drives thoracic aortic aneurysm formation through integrated stress response AbstractBackground and Aims. Thoracic aortic aneurysms and dissections (TAADs) are depicted by aortic medial degeneration characterized by glycan-rich matr

Our paper is here online! EHJ . Excessive glycosylation drives thoracic aortic aneurysm formation through integrated stress response url: academic.oup.com/eurheartj/ar...

Manu got the cover on our lab latest publication. Congratulations @mmgomezheras.bsky.social . So much deserved!

Especially excited to share this research led by @mmgomezheras.bsky.social ! 🤩 We show that a competent CD4+ T cell compartment is key to fostering host-microbiota mutualism and maintaining intestinal barrier integrity, becoming crucial to prevent inflammaging www.science.org/doi/10.1126/...

The August issue of #Science #Immunology is out! This week: T peripheral helper cells expressing IGFL2 contribute to rheumatoid #arthritis; vagal TRPV1+ sensory #neurons protect against #influenza virus infection; & transfer of #Tregs alleviates #inflammaging in mice!

wwwscience.org/toc/sciimmun...

CD4 T cell therapy counteracts inflammaging and senescence by preserving gut barrier integrity Treg cells safeguard the intestinal barrier to prevent inflammaging and senescence in a mouse model of premature aging.

This week's cover, illustrated by the amazing Ashley Mastin, highlights work by @mmgomezheras.bsky.social & al.!

Neutrophils drive vascular occlusion, tumour necrosis and metastasis - Nature Neutrophils actively induce tumour necrosis, driving vascular occlusion, pleomorphic necrosis and metastasis.

I’m happy to share our latest work on tumour necrosis! During my time in the @megeblad.bsky.social lab, we found that tumour necrosis is not a passive phenomenon secondary to tumour growth, but an active phenomenon driven by neutrophils and NETs! Thread below: (1/13)
www.nature.com/articles/s41...

Hoy nos ha visitado Nina Cabezas-Wallscheid (ETH Zurich) para dar un seminario organizado por nuestro comité de Predocs & Postdocs. Nos ha hablado de cómo los componentes de la dieta influyen en la regulación metabólica y epigenética de las células madre hematopoyéticas en estado latente.

Descubren porqué aumenta el riesgo de padecer un grupo de enfermedades hematológicas crónicas. - Centro de Biología Molecular Severo Ochoa Una investigación liderada por el Hospital público 12 de Octubre de la Comunidad de Madrid en colaboración con el Centro de Biología Molecular Severo Ochoa (CBM-CSIC-UAM), ha descubierto el motivo […]

Investigadores del Hospital 12 de Octubre y del CBM, junto a otros colaboradores, descubren porqué aumenta el riesgo de padecer un grupo de enfermedades hematológicas crónicas como las leucemias. www.cbm.uam.es/index.php/20...

KLRG1 identifies regulatory T cells with mitochondrial alterations that accumulate with aging - Nature Aging T cells undergo age-related changes that impair their organismal functions. Here Soto-Heredero et al. show that regulatory T cells characterized by the expression of KLRG1 accumulate with age in both ...

Check out the most recent publication of our team at @cbm-csic-uam.bsky.social. Thanks to #GonzaloSoto-Heredero @enriquegab.bsky.social and all the team! www.nature.com/articles/s43...

Identificado un mecanismo que podría potenciar la inmunoterapia frente al cáncer - Centro de Biología Molecular Severo Ochoa Un equipo del Centro de Biología Molecular Severo Ochoa (CBM-CSIC-UAM) ha hallado un mecanismo celular que podría potenciar la respuesta inmune del organismo frente al cáncer. La investigación, que ap...

Investigadores del grupo de Felipe X. Pimentel han identificado un mecanismo que podría potenciar la inmunoterapia frente al cáncer. Han hallado conexiones inesperadas entre la muerte celular programada y la autofagia o ‘autocanibalismo’ celular.
www.cbm.uam.es/index.php/20...
@csic.es @uam.es

Amazing talk on “New insights into the anatomy of ‘brainwashing’” by Jonathan Kipnis @jonykipnis.bsky.social from @washumedicinebsky.social at #CNIC today 🙇🏼‍♀️🙇🏼‍♀️👏🏻👏🏻👏🏻👏🏻

The scientific community must take a strong and active stand against vaccine revisionism — the false narrative that there is insufficient evidence to support the safety and efficacy of vaccines www.nature.com/articles/s41... #vaccines #immunology #virology

NKG2D-mediated cytotoxicity of CD4 cytotoxic T cells in multiple myeloma Key Points. CD4 CTLs are significantly increased and clonally expanded in the bone marrow of patients with multiple myeloma.CD4 CTLs directly kill myeloma

NKG2D-mediated cytotoxicity of CD4 cytotoxic T cells in multiple myeloma @bloodjournal.bsky.social
doi.org/10.1182/bloo...