Ando Lab

Happy Holidays from @andolab.bsky.social 🥳! In 2025, we were excited to welcome both new and familiar faces to the lab: Steve, Gio, Jon, Katie, Alex, and Kelly supporting lab operations, with Richard joining us as a mad scientist consultant.🌟✨ Wishing everyone a restful holiday season~✨🌟

@andolab.bsky.social undergrads at the beamline! Here are Marcus, Katie, Sarah, and Shaheer collecting data for @diffuseproject.bsky.social with @meisborg.bsky.social and @xiaokunpei.bsky.social 😎💥

Fall beamtime begins! Here is Sarah @andolab.bsky.social ! 😎⚡️

@diffuseproject.bsky.social

#schmidtpolymaths | Schmidt Sciences Announcing the 2025 Schmidt Polymaths: Eight exceptional scientists who embody the future of interdisciplinary research. Selected from universities worldwide, each Schmidt Polymath receives up to $2....

We are elated to *finally* announce that our PI @nozomi-ando.bsky.social has been selected as a 2025 Schmidt Polymath!

Combining geology, evolutionary biology, and biochemistry, we will take our understanding of how life evolved with our planet to the next level!
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www.linkedin.com/posts/schmid...

Marcus @andolab.bsky.social getting ready for fall beamtime for the @diffuseproject.bsky.social 🔥

The Diffuse Project The Diffuse Project

What’s the next PDB? Maybe it’s …the PDB.

We just launched @diffuseproject.bsky.social a structural biology initiative exploring protein motion & rethinking how we generate and use experimental data. Quick 🧵👇

www.diffuse.science

Thanks to generous funding from the Astera Institute and collaborators across the country, we are equipped to tackle a great challenge facing structural biologists today!

Keep up with the Diffuse Project on the official website and follow @diffuseproject.bsky.social

diffuse.science

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We are proud to announce our newest adventure!

Introducing the Diffuse Project, a community-driven effort to predict protein dynamics using the subtle diffuse scattering signal from protein crystals. This collaboration marks a new era for the Ando lab!

as.cornell.edu/news/philant...

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Happy 11th birthday to @andolab.bsky.social ! 🎂 🥳 Also happy to share that I'm a full prof as of July 1 -- thanks to my awesome group, past and present.

We're now looking to grow the team! Looking for someone with amazing protein skills and postdocs excited about evolutionary questions!

After CSHL, Haoyue also visited @chloamphenicol.bsky.social, currently at Rutgers IQB, to talk more #cryoEM ❄️✌️

Woo! It’s Haoyue and her teammates! 🎉 Looks like they had a fabulous time!

Congratulations to everyone who contributed to this amazing work! 🎉
If you want to see how enzymes move during catalytic turnover, check out our latest paper! 🧪🧶

Cornell Chemistry welcomed prospective graduate students with karaoke night! If you've never heard our department chair Tristan Lambert rap, you are missing out! 🎵🎤 #SingingChemists

Congratulations! This is a monumental review 🎉

Happy Holidays from @andolab.bsky.social ! Wishing you all a wonderful 2025 🥳

Happy holidays! This year the Ando Lab celebrates three new PhDs and three new PhD candidates! Congratulations! 🧪

And visit our new lab website at ando.chem.cornell.edu

Thank you so much!

Finally, we are a lab that loves good food, good music, and stable beams. We hope to create a great network of structural biologists, biophysicists, and chemists on Bluesky! 🧪🦋 5/5

Mechanism of Nucleotide-Dependent Allosteric Regulation in Escherichia coli Aspartate Transcarbamoylase Discovered nearly 70 years ago, the allosteric regulation of Escherichia coli aspartate transcarbamoylase (ATCase) is discussed in every biochemistry textbook. ATCase catalyzes the first step in pyrim...

Here is our most recent work on a textbook example of protein allostery, a conclusion to a story 70 years in the making! 🧬🧶 4/5 www.biorxiv.org/content/10.1...

Introduction to diffuse scattering and data collection A long-standing goal in X-ray crystallography has been to extract information about the collective motions of proteins from diffuse scattering: the we…

We also aim to capture correlated motions of proteins using #synchrotron x-ray diffuse scattering. ⚛️ 3/5 www.sciencedirect.com/science/arti...

Conformational Landscapes of a Class I Ribonucleotide Reductase Complex during Turnover Reveal Intrinsic Dynamics and Asymmetry Understanding the structural dynamics associated with enzymatic catalysis has been a long-standing goal of structural biology. A wide range of motions, from small side-chain fluctuations to large doma...

We are interested in the #dynamics and #evolution of enzyme allostery and catalysis. We use #SAXS, #cryoEM, crystallography, and bioinformatics. We apply this to complex enzymes. 2/5 www.biorxiv.org/content/10.1...

Hello Bluesky! 🧪 We are the students in the Ando Lab at Cornell. We study the structure and dynamics of enzymes using biochemical and biophysical tools such as x-rays and cryoEM. 🧬🧶 Here is a brief introduction to our recent work! ⬇️ 1/5