Gene Center Munich @LMU Munich

Blinatumomab in Combined Immune Thrombocytopenia and Antiphospholipid Syndrome | NEJM A CD19-targeted therapy induced remission in a woman with refractory immune thrombocytopenia and antiphospholipid syndrome by stabilizing platelet counts, eliminating pathogenic antibodies, and ena...

📣Excited to share breakthrough work🚀 from @msubklewe.bsky.social and the LMU Hospital team: their bispecific antibody therapy targets disease-causing B cells, offering new hope for treatment-resistant ITP and APS—all without chemotherapy🤩
➡️New England Journal of Medicine www.nejm.org/doi/full/10....

The Bavarian State Minister for Science, Markus Blume, symbolically presents Prof. Marion Subklewe with a check for €3 million. The funding will support ERASE-ML, the first clinical trial financed by the Bavarian Cancer Research Center (BZKF).

📣 @msubklewe.bsky.social and Veit Bücklein lead EASE-AML, a novel cell therapy for aggressive leukemia👏
Funded with €3 million, ERASE-AML is one of the two newly launched clinical trials supported by the Bavarian Cancer Research Center (BZKF). Congratulations, Marion!🥂🥳

👏👏👏🥂🥳

🥳Big shout out to the @hopfnerlab.bsky.social, amazing paper!🤩

Xenotransplantation: Wann können Organe von Tieren Menschen retten? Nach erfolgreichen Transplantationen von Schweineherzen, -nieren und -lungen gibt es neue Hoffnung für Patienten. Genetische Modifikationen und Forschung lösen alte Probleme.

➡️In a recent interview with Süddeutsche Zeitung, our PI Eckhard Wolf discusses the remarkable progress made in xenotransplantation.
sz.de/li.3385188

🏛️ 200 Years of LMU in Munich 🎓 Founded in 1472, relocated from Landshut to Munich in 1826 — today LMU celebrates 200 years in Munich and inaugurates Prof. Dr. Matthias H. Tschöp as President.

🥳And here’s the next publication from the Bohlen Lab — congratulations!👏

Cancer therapy made to measure Marion Subklewe and Sebastian Kobold are getting the immune system to target tumors and opening up new perspectives for patient-specific treatments.

🌟Don' t miss this article about personalized cancer therapy featuring our PI, Marion Subklewe
www.lmu.de/en/about-lmu...
@msubklewe.bsky.social

Congratulations to the whole team on this great publication!👏🥂🥳

Big news this week: results of a very competitive @erc.europa.eu CoG call are in, and I’m happy that our project mitoSCALES (scales of mitochondrial stress response) is among the ~11% funded. Recruiting will begin soon—get in touch if you want to hop on board for the ride!
#ERCCoG #Mitochondria #GCM

🥳🥂Huge congratulations to Jonathan Bohlen on being awarded an Emmy Noether Grant by @dfg.de 😊🤩
His project addresses a central open question in immunology: how mRNA translation governs the function of T cells.
www.genzentrum.uni-muenchen.de/news-events/...
@jonathanbohlen.bsky.social

Heterogeneous template-dependent transcription dynamics of T7 RNAP revealed by single-molecule imaging | PNAS Bacteriophage T7 RNA polymerase (T7 RNAP) is commonly used for large-scale RNA synthesis in science and industry. Although T7 RNAP exhibits high pr...

📣Publication alert!
The Stigler lab deciphers why T7 RNA polymerase experiences premature stalls during RNA synthesis and identifies two distinct pausing mechanisms.👏👍
| PNAS www.pnas.org/doi/10.1073/...

🤩What a year! Two of our PIs have already secured ERC grants — and today comes the third: Lucas Jae has been awarded an ERC Consolidator Grant! Congratulations!🥂🎆
@jaelab.bsky.social @lmumuenchen.bsky.social @erc.europa.eu
www.genzentrum.uni-muenchen.de/news-events/...
www.lmu.de/en/newsroom/...

How to get science back into policymaking Misunderstanding and hubris have broken public trust in governments’ use of science, but it can be restored.

Misunderstanding and hubris have broken public trust in governments’ use of science, but it can be restored

go.nature.com/3YkIXfu

📣Publication alert!
Collaboration between Bartholomew lab and @hopfnerlab.bsky.social shows that INO80 positions nucleosomes at specific genomic sites by sensing intranucleosomal DNA shape and stalling at rigid DNA via its Arp5 subunit.
authors.elsevier.com/c/1m9kd3vVUP...
@mdanderson.bsky.social

Colliding ribosomes signal cellular stress LMU researchers uncover the mechanism by which ribosomes raise alarms in the cell.

📣Publication alert!
A team led by Roland Beckmann shows: Ribosome collisions activate the kinase ZAK and thus trigger the ribotoxic stress response — a key mechanism of the cellular stress defense. More about it here👇
www.lmu.de/en/newsroom/...

🧐Curious about what has happened at the Gene Center over the past 5 years? Take a look at our hot-off-the-press report.🤩
www.genzentrum.uni-muenchen.de/institute/ab...

17 LMU scholars make Highly Cited Researchers list from Clarivate The latest international publication analysis recognizes 17 LMU scholars as among the most successful in their field.

www.lmu.de/en/newsroom/...

🥳 Veit Hornung, Marion Subklewe and Christoph Klein are again among the most influential researchers. Congratulations! 🤩
@v-hornung.bsky.social @msubklewe.bsky.social
@lmumuenchen.bsky.social

😀More details on the ERC Synergy Grant winners @lmumuenchen.bsky.social 👇
youtu.be/xAnePmLGjEA

🥳 Huge congratulations to Roland Beckmann and his team on being awarded an ERC Synergy Grant! We are very proud of you! 👏🏻 🥂
@beckmannlab.bsky.social

📣Join us for a guest seminar by Atlanta Cook from the University of Edinburgh
🕐TODAY at 13:00
▶️Lynen Lecture Hall.
Title: “Seeing Double: Integrative structural approaches to unravel nuclear dsRNA recognition by the NF45-NF90 complex.”
We're looking forward to seeing you🤗
@edinburgh-uni.bsky.social

🧬 From 14–16 Nov, join us at the #DeutschesMuseum for “Stem Cell Stories” — an interactive exhibition on stem cells, identity & epigenetics.
🎙️ Roundtable discussion on #AI in stem cell research & its ethical challenges on 📅14 Nov ⏲️18:30.
#StemCells #Epigenetics #AIinBiomedicine #HelmholtzMunich

Alumnus Stephan Kothrade: from chemistry student to CTO at BASF The chemistry PhD describes his journey from the lecture halls of LMU to the boardroom of BASF and the current challenges facing the chemical industry.

🎓 Great to see LMU highlighting alumnus Stephan Kotrade in an alumni portrait! He fondly recalls the inspiring lectures of Prof. Ernst-Ludwig Winnacker, founding director of the Gene Center Munich — where innovation and curiosity still drive research today🚀
www.lmu.de/en/newsroom/...

📣Don't miss this amazing publication from the Hopfner lab👇

🤩Congratulations to Lukas Milles on being awarded an ERC Starting Grant – we’re proud to have you at the Gene Center! 👏🥂
@lfmilles.bsky.social @erc.europa.eu @lmumuenchen.bsky.social

Marleen Bérouti (@marleenberouti.bsky.social) from the lab of Veit Hornung, Ludwig-Maximilians-Universität München. 👏🏾 2/

🥳Congratulations, Marleen!👏

LMU remains the best German university In the latest Academic Ranking of World Universities, LMU ranks among the world’s top 50 research-intensive universities.

LMU remains the best German university www.lmu.de/en/newsroom/...

Nanomachines made to measure: protein design with artificial intelligence Biophysicist Lukas Milles is a researcher at LMU’s Gene Center Munich. He investigates how to design completely new proteins with the help of deep learning.

Check out this LMU article on Lukas Milles’ research — one of our rising talents!😉
Nanomachines made to measure: protein design with artificial intelligence www.lmu.de/en/newsroom/...
@lfmilles.bsky.social