Christophe Lachance-Brais

A sad development for all of the world, as the American scientific enterprise yielded so many great advances of the modern age.

U.S. government has lost more than 10,000 STEM Ph.D.s since Trump took office A Science analysis reveals how many were fired, retired, or quit across 14 agencies

Incredible self own for the US. The damage being done to the US scientific enterprise is generational. We will look back on this as a tipping point where the US chose all on its own to stop leading the world in science.

www.science.org/content/arti...

This is a wild story

Proud to be Canadian 🇨🇦 When the world closes, we reach out. When war looms, we rise for peace. When our friends need us, we answer the call. Join us, and together we can create an international order of respect and mutual interests rather than intimidation and subordination.

Extraordinaire discours. Je suis fier que vous nous représentez avec force, valeur et sagesse. #canadastrong 🇨🇦

Pour un comptable, Mr. Legault à été rapide à perdre le surplus budgétaire du PLQ de Mr. Couillard. En identité, son approche bâton plutôt que carotte a éloigné le Québec des idéaux de la révolution tranquille pour le rapprocher plutôt de la période de la grande noirceur. Merci, mais au prochain(e).

I wish the opinion piece described more in detail the potential flaws and logical errors of the initial studies and how they could be mitigate or followed up on.

Programmable Aptamer-Controlled Fibrinogenesis Using Dynamic DNA Networks and Synthetic Transcription Machineries ConspectusFibrinogenesis─the transformation of fibrinogen to fibrin─is one of the most significant physiological pathways regulating hemostasis by promoting clot formation at vascular injury sites. Th...

A very nice account from the Willner lab : Programmable Aptamer-Controlled Fibrinogenesis Using Dynamic DNA Networks and Synthetic Transcription Machineries | Accounts of Chemical Research pubs.acs.org/doi/abs/10.1...

This may be biased and a little selfish, but I don't think AI will be doing all scientific research in 2050. I think all research will be assisted by AI, but they will complement the strengths and weaknesses of human researchers.

The story of this set has been excellent. With the 11 episodes, the podcast and the complexe character interactions, it feels like a level up from the previous storylines. I enjoyed it, and I'm pumped for it's release!

I'd like to see a head-to-head with DNA Bricks, as it seems the more similar tech

Martin Kulldorff & @MartinKu...•9/10/23 S.•• "One of the most disturbing images of the Covid-19 pandemic was when a teacher .. forced a mask on a crying toddler .. In some ways, the U.S. government.. treated all of us like toddlers, compelling us to endure draconian Covid measures" - @HRaleighspeaks

RFK Jr’s ACIP pick, Martin Kulldorff, said one of the most disturbing images from the pandemic was a toddler crying about having to wear a mask. I see toddlers cry about everything all the time, and I found it far more disturbing to see refrigerator trucks full of body bags outside of the hospitals…

"God's detox" where is our world going...

@mark-carney.bsky.social J'espère que vous êtes sûre de ce que vous faites... On semble donner une victoire à Trump quand il continue à ouvertement bafoué notre pays, nous menacer d'une invasion. Est-ce déjà le temps pour un deal? On ne vous a pas élu pour vous plier aux américains après tout...

Misha Lukin is now talking about doing quantum computing and error correction with arrays of neutral Rydberg atoms. I wrote about that here. #Helgoland2025
www.quantamagazine.org/the-best-qub...

An overlooked bonding motif appears in many more proteins than was previously realised Covalent nitrogen-oxygen-sulfur linkages could be a new target for potential drugs

Despite huge protein databanks and the use of AI tools like AlphaFold, a new previously overlooked covalent bonding motif has been revealed. #ChemSky #BioSky

Ah I see , I apologize I misunderstood your point

I don't know, it seems like a good idea and something that machine learning can excel at (recognizing patterns). Of course human final verification is advised but I think for those who aren't experts it is a great way to learn about the species we encounter in the wild.

Definitely important to share, but hardly an insight. That man has always been antivax and he was put there specifically by antivaxxers for antivaxxers.

We have two new positions, a PhD and a Post doc at #InstituteofBiologyLeiden within our @microclockerc.bsky.social #ERCSyG project to discover interaction of #circadianclocks between Bacillus subtilis and Arabidopsis

please share these with your network! 🙏

links below👇
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Thank you for taking the initiative and tackling the critical dangers AI development. We all want to have a future where AIs and humans work harmoniously together, rather than a dystopia pitting humans against machines.

AI RNA Design: Generating Functional Molecules with Machine Learning! AI RNA design: Advanced machine learning techniques create functional RNA molecules, from CRISPR guides to innovative toehold switches.

Is it possible to leverage AI to create functional RNAs? Well, from now yes! 🧪 Subscribe to get more like this 👉 plentyofroom.beehiiv.com/p/ai-rna-des... #AI #biotech

Thérapie génique : première mondiale au CHU Sainte-Justine La nouvelle technique permet de corriger pratiquement n'importe quelle mutation génétique et a essentiellement « guéri » un jeune homme de 18 ans.

Another successful treatment in the rapidly expanding field of nucleic acid therapeutics! Glad to see this one coming from close to home, following intense collaboration between Canadian 🇨🇦and American 🇺🇸 doctors and scientists. 🧪🧬

ici.radio-canada.ca/nouvelle/216...

A prescient article that goes beyond a single scandal to make a general "état de fait" of AI slop seeping through every aspect of society. On AI slop, "(AI tools) are not deployed by people trying to supplement or enrich their work and potential, but by those looking to automate it away entirely."

Trump’s NIH And NSF Cuts Estimated To Cost The U.S. Economy $10 Billion Annually Economists find public R&D drives U.S. productivity growth — and pays for itself

Thorough economic analysis of the impact of funding basic research. The US🇺🇸 had high basic science investment levels before and reaped the rewards, other countries, like Canada🇨🇦, should learn from that. 🧪 www.forbes.com/sites/johndr...

Baby Is Healed With World’s First Personalized Gene-Editing Treatment

What a hearthwarming story of a revolutionary gene-editing breakthrough! Hopefully little KJ will be the first of many patients with a rare genetic diseases to be cured with base-editing. 🧪🧬 www.nytimes.com/2025/05/15/h...

I applaud #OpenAI 's decision to keep the company non-profit. As a frequent ChatGPT user, I feel more comfortable knowing the AI is not geared to maximize shareholder income.

Architectural RNAs: A class of long noncoding RNAs functioning as scaffolds for membraneless organelles Architectural RNAs (arcRNAs) are long noncoding RNAs that serve as structural scaffolds for membraneless organelles (MLOs), facilitating cellular orga…

Having a great time reading this review on architectural RNA (arcRNA). Do some common structural pattern used in nucleic acid nanotechnology, like DX junctions, could also be found in cells? 🧪🧬 www.sciencedirect.com/science/arti...

Mes félicitations à Mark Carney pour sa victoire électorale! J'espère qu'il fera bon sur sa parole et travaillera avec tout les autres partis, néo-democrate, conservateurs et bloquiste, pour présenter un front unis Canadien 🇨🇦 Elbows up

Quite a witty way to approach a sad situation. Best of luck to you and your research