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Nadia Nikulin

@nadianikulin

PhD Candidate, DΓΆrr Lab at Cornell Microbiology, studying microbial responses to antimicrobial compounds and the host innate immune system πŸ§«πŸπŸ”¬πŸ§¬ πŸ‡ΊπŸ‡¦ by birth, currently in πŸ‡ΊπŸ‡Έ

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11.11.2024
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Latest posts by Nadia Nikulin @nadianikulin

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Antibiotics accumulate in Klebsiella pneumoniae liver abscesses but fail to eliminate antibiotic-tolerant populations | PNAS Liver abscesses caused by hypervirulent Klebsiella pneumoniae (hvKp) can lead to severe metastatic complications, with mortality rates ranging from...

Thrilled to share our latest paper on antibiotic treatment failure of Klebsiella pneumoniae liver abscesses

www.pnas.org/doi/full/10....

@drwalkermsbanta.bsky.social

01.12.2025 12:49 πŸ‘ 7 πŸ” 4 πŸ’¬ 0 πŸ“Œ 1
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Prevalence and mechanisms of high-level carbapenem antibiotic tolerance in clinical isolates of Klebsiella pneumoniae Author summary Bacteria can survive exposure to antibiotics by constantly repairing cellular damage induced by the drug. This β€œantibiotic tolerance” enables diverse bacteria to survive long enough to ...

First paper of my PhD @doerrlab.bsky.social is up! We characterized meropenem tolerance in Enterobacterales species, and then further dissected tolerance mechanisms in Klebsiella pneumoniae. journals.plos.org/plospathogen...

03.02.2026 18:07 πŸ‘ 35 πŸ” 17 πŸ’¬ 0 πŸ“Œ 0

Tn7 family bacterial transposons known for tightly controlled target site selection are distributed across Asgard and archaeal groups https://www.biorxiv.org/content/10.1101/2025.07.27.667033v1

28.07.2025 04:17 πŸ‘ 9 πŸ” 4 πŸ’¬ 0 πŸ“Œ 3
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[Μ…Μ²P][Μ…Μ²A][Μ…Μ²R][Μ…Μ²A][Μ…Μ²D][Μ…Μ²I][Μ…Μ²G][Μ…Μ²M]

[Μ…Μ²S][Μ…Μ²H][Μ…Μ²I][Μ…Μ²F][Μ…Μ²T]

𝘏𝘺π˜₯𝘳𝘰𝘨𝘦𝘯𝘰𝘣𝘒𝘀𝘡𝘦𝘳 isolated from Yellowstone hot springs use both oxygen (aerobic) and elemental sulfur (anaerobic) respiration AT THE SAME TIME. Until now, cells were thought to toggle between the twoβ€”not do both simultaneously

www.nature.com/articles/s41...

09.03.2025 19:49 πŸ‘ 68 πŸ” 15 πŸ’¬ 3 πŸ“Œ 5
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Applications are open for the Weill Institute Emerging Scholars Symposium @ Cornell! Senior PhD students and, now, postdocs interested in networking & presenting their work in cell & molecular biology should apply by April 14, 2025. Please repost! wicmb.cornell.edu/emerging-sch...

04.03.2025 22:34 πŸ‘ 7 πŸ” 5 πŸ’¬ 0 πŸ“Œ 0
NOT-OD-25-068: Supplemental Guidance to the 2024 NIH Grants Policy Statement: Indirect Cost Rates NIH Funding Opportunities and Notices in the NIH Guide for Grants and Contracts: Supplemental Guidance to the 2024 NIH Grants Policy Statement: Indirect Cost Rates NOT-OD-25-068. OD

1. Today the NIH director issued a new directive slashing overhead rates to 15%.

I want to provide some context on what that means and why it matters.

grants.nih.gov/grants/guide...

08.02.2025 00:18 πŸ‘ 7033 πŸ” 4102 πŸ’¬ 257 πŸ“Œ 902
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Warren: "He can stand there, smile at you and say, 'anybody can vaccinate their kids who wants to,' but he literally could bankrupt the vaccines manufacturers with the power he will have. And since he's got a financial incentive to do that, we cannot trust him in that job."

30.01.2025 01:38 πŸ‘ 46067 πŸ” 10820 πŸ’¬ 606 πŸ“Œ 346
An image showing buildings with snow on the ground and trees with no leaves. The sky is filled with purple and grey and blue along with some light clouds shining in dark orange-pink. The sun looks like a beam of light

An image showing buildings with snow on the ground and trees with no leaves. The sky is filled with purple and grey and blue along with some light clouds shining in dark orange-pink. The sun looks like a beam of light

The prettiest sunset tonight πŸŒ…

09.01.2025 22:13 πŸ‘ 4 πŸ” 0 πŸ’¬ 0 πŸ“Œ 0

Does anyone have any experience using Halo in Gran-negative bacteria for live cell imaging? I am having mixed results

07.01.2025 23:35 πŸ‘ 0 πŸ” 0 πŸ’¬ 0 πŸ“Œ 0
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More vaccines exist today than 40 years ago. That's a good thing. Every new vaccine means fewer deadly diseases and more lives savedβ€”that's the ultimate goal of scientific progress.

Are these health interventions evil too, according to anti-vaccine activists?

Scientific progress doesn’t stand still. And it definitely isn’t a conspiracy.

Read more about this at ImmunoLogic ⬇️⬇️

news.immunologic.org/p/more-vacci...

21.12.2024 21:54 πŸ‘ 1101 πŸ” 148 πŸ’¬ 17 πŸ“Œ 8
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Just a reminder that in 2019, RFK Jr.'s anti-vaccine misinformation campaign helped cause a measles outbreak in Samoa that killed 83 people, mostly kids.

Do you really want him to lead the Department of Health and Human Services?

17.12.2024 22:14 πŸ‘ 45691 πŸ” 13484 πŸ’¬ 2116 πŸ“Œ 731
A clear gel illuminated by UV light so it is a purple-pink color with bright pink-orange single bands of DNA and standard visible.

A clear gel illuminated by UV light so it is a purple-pink color with bright pink-orange single bands of DNA and standard visible.

I had a rich GC region I was trying to amplify. Q5 and Phusion failed repeatedly. OneTaq FTW! πŸ₯³πŸ§¬

14.12.2024 22:57 πŸ‘ 3 πŸ” 0 πŸ’¬ 0 πŸ“Œ 0

Really informative. Like a Bluesky version of a review article! Thank you for sharing

07.12.2024 15:42 πŸ‘ 3 πŸ” 0 πŸ’¬ 0 πŸ“Œ 0
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OmpA controls order in the outer membrane and shares the mechanical load | PNAS OmpA, a predominant outer membrane (OM) protein in Escherichia coli, affects virulence, adhesion, and bacterial OM integrity. However, despite more...

Beautiful study-
Making it stronger, permeable and more compressive:

www.pnas.org/doi/10.1073/...

05.12.2024 11:03 πŸ‘ 17 πŸ” 6 πŸ’¬ 0 πŸ“Œ 1
Backside of a petri dish containing pink colored agar, with 4 roundish big colonies growing

Backside of a petri dish containing pink colored agar, with 4 roundish big colonies growing

Side view of a Petri dish showing round fluffy white colonies growing

Side view of a Petri dish showing round fluffy white colonies growing

Top view of a Petri dish showing big fluffy white colonies growing on the surface of agar colored pink

Top view of a Petri dish showing big fluffy white colonies growing on the surface of agar colored pink

Found the cutest contaminant today! The agar was LB so the pink is from whatever this microorganism is secreting #microbiology #contaminant

03.12.2024 21:41 πŸ‘ 6 πŸ” 0 πŸ’¬ 0 πŸ“Œ 0

Wing Hall is spectacular! I have always loved the exterior. Hopefully the interior improves soon

03.12.2024 01:34 πŸ‘ 0 πŸ” 0 πŸ’¬ 0 πŸ“Œ 0

Another great explanation! This time about the importance of Vitamin K. Vitamin K injections after birth have reduced the incidences of devastating brain bleeds in newborns

02.12.2024 21:29 πŸ‘ 7 πŸ” 4 πŸ’¬ 1 πŸ“Œ 0
A grassy field is pictured with a parking lot on the top left corner. The bottom half of the field is covered in dirt along with excavators and other large construction vehicles/equipment. There is a slight reflection on the photo because it was taken from inside of a well-lit building

A grassy field is pictured with a parking lot on the top left corner. The bottom half of the field is covered in dirt along with excavators and other large construction vehicles/equipment. There is a slight reflection on the photo because it was taken from inside of a well-lit building

We no longer have a beautiful view 😩

02.12.2024 21:26 πŸ‘ 0 πŸ” 0 πŸ’¬ 1 πŸ“Œ 0
A grey and light orange speckled cat laying on her side with her front paws curled and her head is turned up so that her orange chin is visible

A grey and light orange speckled cat laying on her side with her front paws curled and her head is turned up so that her orange chin is visible

Floofy paws for #Caturday

30.11.2024 16:48 πŸ‘ 10 πŸ” 1 πŸ’¬ 0 πŸ“Œ 0

Another reason to get the HPV vaccines

18.11.2024 15:38 πŸ‘ 1 πŸ” 0 πŸ’¬ 0 πŸ“Œ 0

@scientistswanda.bsky.social is an amazing scientific communicator. Check out his video on all things polio

18.11.2024 15:19 πŸ‘ 1 πŸ” 0 πŸ’¬ 1 πŸ“Œ 0

Please add me @nadianikulin.bsky.social

18.11.2024 05:20 πŸ‘ 0 πŸ” 0 πŸ’¬ 0 πŸ“Œ 0

I’d love to be added!

17.11.2024 04:04 πŸ‘ 1 πŸ” 0 πŸ’¬ 1 πŸ“Œ 0
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Report: Every dollar of NIH research funding doubles in economic returns Research funded by the National Institutes of Health (NIH) generated $2.46 in economic activity for every $1 of funding in 2023, a total of $92.9 billion, according to an

NIH research funding supported 412,000 jobs in 2023 & doubled economic returns www.fiercebiotech.com/research/rep... #NIH #research #funding

16.11.2024 16:22 πŸ‘ 207 πŸ” 82 πŸ’¬ 1 πŸ“Œ 7
Cartoon depicting an orange dog in a lab coat sitting by a microscope, surrounded by flames

Cartoon depicting an orange dog in a lab coat sitting by a microscope, surrounded by flames

My introductory post: I am a PhD Candidate and will be on the job market for a postdoc or research scientist position sometime in 2025. I currently study Gram-negative ESKAPE pathogens and their responses to antibiotics and the host innate immune system. Glad to be here!

16.11.2024 22:39 πŸ‘ 11 πŸ” 0 πŸ’¬ 0 πŸ“Œ 0

Come work at Cornell! We have an amazing interdisciplinary environment

14.11.2024 05:51 πŸ‘ 6 πŸ” 5 πŸ’¬ 0 πŸ“Œ 0
Antibiotic discovery in Streptomyces bacteria | Doctoral Training Partnership HUTCHINGS_J25DTP1

Another fully funded 4 year PhD in our group. Understanding the role of the conserved WblA protein in coordinating antibiotic production with sporulation in Streptomyces bacteria. Please RB.
biodtp.norwichresearchpark.ac.uk/projects/ant...

12.11.2024 09:35 πŸ‘ 15 πŸ” 23 πŸ’¬ 0 πŸ“Œ 0

I really liked this paper! Check it out if you have any interest in AMR ESKAPE pathogen infection biology and utilizing alternatives to animal models

12.11.2024 14:07 πŸ‘ 1 πŸ” 0 πŸ’¬ 0 πŸ“Œ 0

I loved this paper! Beautiful work. I am also interested in studying the lesser-known opportunistic AMR pathogens. And I appreciated the use of engineering to study pathogenesis without the use of mice. Well done!

12.11.2024 14:05 πŸ‘ 1 πŸ” 0 πŸ’¬ 1 πŸ“Œ 0
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First bluesky post needs to be a cat 🐱. This is Whiskers, ironically named since hers blend into her fur

11.11.2024 14:10 πŸ‘ 4 πŸ” 0 πŸ’¬ 0 πŸ“Œ 0