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Lucie Berkovitch

@lucieberko

MD. PhD. Psychiatrist and researcher at GHU Paris psychiatrie & neurosciences - Psychedelics, consciousness and psychiatry https://lucie-berkovitch.fr https://scholar.google.com/citations?user=7ShQ

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Latest posts by Lucie Berkovitch @lucieberko

Lucie Berkovitch Site personnel de Lucie Berkovitch, psychiatre et chercheuse spécialisée dans l'utilisation des psychédéliques pour le traitement de la santé mentale

Mon site internet personnel est en ligne !

lucie-berkovitch.fr/fr

Il rassemble mes publications, interventions en congrès ou dans les médias, et les éléments principaux de mon parcours🎢

🌈 Vous verrez, je me suis fait plaisir avec les liens cliquables qui ont une petite touche #psychédélique !

19.01.2026 14:39 👍 0 🔁 0 💬 0 📌 0
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My personal website is now live!

lucie-berkovitch.fr/en

It showcases my publications, talks, and media interviews, as well as the key milestones of my career 🎢

🌈 You'll see that I had fun with the clickable links, which have a slightly #psychedelic touch!

19.01.2026 14:39 👍 4 🔁 1 💬 1 📌 0

Et au passage je vous souhaite à toutes et à tous une très belle année 2026 ✨

🎧 Bonne écoute !

03.01.2026 15:31 👍 0 🔁 0 💬 0 📌 0

L'occasion d'aborder les contrevérités circulant sur ces substances et de souligner leur potentiel thérapeutique 💊

Un grand merci à @quentinlafay.bsky.social, @juliettemouellic.bsky.social et à toute l'équipe !

03.01.2026 15:31 👍 2 🔁 0 💬 2 📌 0
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Champignons, LSD : un espoir pour la psychiatrie ? Les recherches sur les psychédéliques avancent et interrogent. Ces substances, longtemps interdites, sont de nouveau utilisées pour traiter les souffrances de patients touchés par une dépression, ou e...

🌚 Questions du soir, bonjour ! @questionsdusoir.bsky.social

🎙️ Emission de rentrée consacrée aux #psychédéliques en direct hier sur @franceculture.fr en compagnie de @vincent-verroust.bsky.social de la Société psychédélique française @psychedelique-fr.bsky.social
www.radiofrance.fr/francecultur...

03.01.2026 15:31 👍 8 🔁 2 💬 3 📌 0

💊 We conclude that ketamine may induce psychotic-like symptoms by disrupting consciousness.

📣 Please enjoy, share, and give feedback!

Many thanks to my colleagues who supported me in this epic tale!
Raphaël Gaillard, @standehaene.bsky.social, @thomasandrillon.bsky.social and Alexandre Salvador

13.11.2025 19:18 👍 1 🔁 0 💬 0 📌 0
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👀 We used a visual masking paradigm and found that healthy volunteers under ketamine were less able to perceive a digit.

🧠 These effects were related to a decreased early brain activity in EEG (N1) and to the intensity of experienced psychotic-like symptoms.

13.11.2025 19:18 👍 0 🔁 0 💬 1 📌 0
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Ketamine disrupts consciousness in healthy participants in relation with psychotic-like symptoms Ketamine is an NMDA-receptor antagonist, which alters the state of wakeful consciousness at high doses. At lower doses, it induces reversible psychotic-like symptoms and has been used as a pharmacolog...

" #Ketamine disrupts #consciousness in healthy participants in relation with #psychotic-like symptoms"

🥸 This is the title of our last preprint @biorxiv-neursci.bsky.social giving some insights on how ketamine at subanesthetic doses mimicks psychosis symptoms!

www.biorxiv.org/content/10.1...

13.11.2025 19:18 👍 7 🔁 4 💬 1 📌 1

Thank you so much @haunted.audio, it is an amazing series!

12.09.2025 15:29 👍 1 🔁 0 💬 1 📌 0

This amazing series by Tim Hayward and Richard Ward @haunted.audio (🙏🙏🙏) also featured renowned neuroscientists such as @christimmermann.bsky.social, @katrinpreller.bsky.social, Gul Dölen, as well as nurses, historians, philosophers, sociologists, etc.

Enjoy! 🎧

12.09.2025 15:29 👍 2 🔁 2 💬 0 📌 0
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BBC Radio 4 - Understand, The Trip, 10. Unknown unknowns What more is there to learn about psychedelics? Tim Hayward makes a case for curiosity.

In the first episode, I explain what is specific about psychedelics as treatment in psychiatry.
In last episode, dealing about the future of psychedelics, I talk about the possible dissociation between the psychedelic experience and the therapeutic effects:

www.bbc.co.uk/programmes/m...

12.09.2025 15:29 👍 2 🔁 1 💬 1 📌 0

🎙️ I am very proud to have participated (with a very strong French accent) to the BBC Radio 4 program Understand entitled "The Trip", about the science, culture, history and future of psychedelics 🌈

www.bbc.co.uk/programmes/m...

12.09.2025 15:29 👍 6 🔁 4 💬 1 📌 0
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A few moments from our ongoing MESEC 2025 Workshop (‘Centering Experience in Mental Health: Uniting Psychiatry and Consciousness Science’) at the beautiful Lago di Bolsena!

@lucieberko.bsky.social
@tehseennoorani.bsky.social

04.09.2025 08:31 👍 11 🔁 3 💬 0 📌 0
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Disruption of consciousness depends on insight in obsessive-compulsive disorder and on positive symptoms in schizophrenia Abstract. Disruption of conscious access contributes to the advent of psychotic symptoms in schizophrenia and could also explain lack of insight in other p

🚨 New article in #NCONSC

Disruption of consciousness depends on insight in obsessive-compulsive disorder and on positive symptoms in schizophrenia
academic.oup.com/nc/article/2...

@lucieberko.bsky.social

#consciousness
🧠🧪

26.08.2025 22:05 👍 3 🔁 3 💬 0 📌 0

🙏 A huge thanks to my co-authors Selim Tümkaya, Bengü Yücens, Mohamed Gunduz and Maxime Maheu @maheump.bsky.social

03.09.2025 10:04 👍 2 🔁 0 💬 0 📌 0

In sum :
✅ Consciousness disruption translates into various symptomatic expressions according to the psychiatric disorder
✅ In patients with OCD, consciousness disruption delineates two distinct subgroups in terms of cognitive deficits and clinical features

03.09.2025 10:04 👍 3 🔁 0 💬 1 📌 0

‼️ Patients with SCZ have consciousness disruption in relation with positive symptoms
‼️ Patients with OCD who have a poor insight exhibit similar consciousness deficits as patients with schizophrenia
‼️ Patients with OCD and good insight performed similarly to controls ⤵️

03.09.2025 10:04 👍 1 🔁 0 💬 1 📌 0

We compared consciousness measures in patients with #OCD and with #schizophrenia as a function of symptom relevant dimensions.

😮 We found pretty surprising results: ⤵️

03.09.2025 10:04 👍 1 🔁 0 💬 1 📌 0
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Disruption of consciousness depends on insight in obsessive-compulsive disorder and on positive symptoms in schizophrenia Abstract. Disruption of conscious access contributes to the advent of psychotic symptoms in schizophrenia and could also explain lack of insight in other p

🗞️ First article as #lastauthor published in Neuroscience of Consciousness @nconsc.bsky.social 🥳 🥳 🥳

academic.oup.com/nc/article/d...

🔍 In this study, we examine how #consciousness disruption translates into clinical manifestations in different #psychiatric disorders. 🧶⤵️

03.09.2025 10:04 👍 11 🔁 4 💬 3 📌 1
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Les substances hallucinogènes peuvent-elles soigner l’alcoolisme et la dépression ? La dépendance à l’alcool serait, selon le ministère de la Santé, responsable chaque année de 49 000 décès. Mais selon une étude menée par le CHU de de Nîmes, les champignons hallucinogènes pourraient ...

Berko on air de bon matin sur @franceculture.fr

www.radiofrance.fr/francecultur...

16.08.2025 10:44 👍 2 🔁 1 💬 0 📌 0

Thanks to all my collaborators!!

16.08.2025 10:43 👍 1 🔁 0 💬 0 📌 0

Overall, our results underscore that a univariate data-driven symptom improvement measure can be more sensitive to detect antidepressant action and is specifically associated with baseline neurobehavioral features.

16.08.2025 10:43 👍 1 🔁 0 💬 1 📌 0
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Moreover, improvement was more robustly predicted by baseline neural and clinical features under antidepressant compared to placebo.

16.08.2025 10:43 👍 1 🔁 0 💬 1 📌 0
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However, the intensity of antidepressant and placebo response significantly differs (in previous papers on this dataset, scale level measures of improvement could not distinguish between the two).

16.08.2025 10:43 👍 1 🔁 0 💬 1 📌 0
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We applied principal component analysis (PCA) on the variations of items from multiple clinical scales and strikingly observed a similar pattern of clinical improvement across antidepressant and placebo arms.

16.08.2025 10:43 👍 2 🔁 0 💬 1 📌 0
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We explored clinical response in patients with major depressive disorder from the EMBARC dataset.

16.08.2025 10:43 👍 1 🔁 0 💬 1 📌 0
A common symptom geometry of mood improvement under sertraline and placebo associated with distinct neural patterns | Psychological Medicine | Cambridge Core A common symptom geometry of mood improvement under sertraline and placebo associated with distinct neural patterns - Volume 55

New paper out in Psychological Medicine where we found that #sertraline and #placebo strikingly induce a similar clinical improvement predicted by distinct neural configurations!

doi.org/10.1017/S003...

16.08.2025 10:43 👍 4 🔁 1 💬 1 📌 0

A big thank to my colleagues Baptiste Fauvel, @katrinpreller.bsky.social and Raphaël Gaillard

Please find here the link for free access until 27th of July:
authors.elsevier.com/a/1lE1NY3M3l...

Enjoy!!

08.06.2025 19:22 👍 5 🔁 0 💬 0 📌 0

🧠 No fewer than 81 articles are described in depth and put together to provide an overview of the neurocognitive effects of psilocybin in healthy volunteers and people with medical conditions.

😅 Believe me, it was quite a long journey before it was published in Neuroscience & Biobehavioral Reviews!

08.06.2025 19:22 👍 3 🔁 0 💬 1 📌 0
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Neurocognitive effects of psilocybin: A systematic and comprehensive review of neuroimaging studies in humans Psilocybin is a psychedelic serotonergic compound that is renowned for its potent psychoactive effects. Over the past 15 years, an increasing number o…

📚 Just another #review about #psychedelics? Maybe... but in this paper we systematically reviewed ALL neuroimaging articles involving #psilocybin intake in humans.
www.sciencedirect.com/science/arti...

08.06.2025 19:22 👍 21 🔁 6 💬 1 📌 0