Rosa Uribe, PhD

Call for Papers! Submit to the Splicing in Development and Disease special issue

Deadline extended: Submit your research on splicing in development and disease to the Differentiation special issue led by Guest Editors Natoya Peart and Karine Choquet by June 30, 2026. Learn more: https://www.sciencedirect.com/special-issue/322731/splicing-in-development-and-disease

a picture of a woman covering her mouth with her hand and a quote that says may the odds be ever in your favor . ALT: a picture of a woman covering her mouth with her hand and a quote that says may the odds be ever in your favor .

Wishing everyone luck as we collectively get through the next week. May the odds be ever in your favor!

Please check out our new preprint! Using single cell analysis paired with HCR to visualize transcript localization we have identified cell and tissue-specific expression of various genes encoding tubulins, kifs, and dyneins during neural crest development!

Awesome! Congrats!

Oh wow. Ok, good to know!

😂

a clown is sitting at a desk with a computer Alt: a clown is sitting at a desk with a computer looking emotionless

So I asked my capstone undergrad class today if anyone had heard of or knew what microarrays were...

Graphic with scientific image and text: The image features a dark, high-resolution microscopy view of a small organism shown from above, with green and red fluorescent signals highlighting internal structures against a black background. The scientific image is placed at the top and framed by a wide light blue background. Below the image, bold white sans-serif text appears inside dark magenta rectangular boxes reading, “HOW GUT MICROBES INFLUENCE THE HEART.” In the lower right corner is a dark blue “MAX DELBRÜCK CENTER” logo.

Some gut bacteria talk to the heart – through the brain.

Researchers at the #mdcBerlin identified a gut–brain–heart pathway in zebrafish. A microbial metabolite (IAA) influenced specific neurons and heart function.

🔗 Full story: www.mdc-berlin.de/news/news/gu...

#CardiovascularResearch

idk that seems to be the understatement of the week. this is actually happening, postdocs and RAs are being let go, and projects falter. 'could face funding gaps'? this is actually happening at a large scale. 'Worry' doesnt reflect the existential crisis that many of my colleagues are in.

Thanks for clarifying that.

Hi Coleen, that is a fact? Do you have a source for that?

Placing an update here for those who want to read more about the SGA Github www.uribelabrice.com/single-cell-...

Did you teach out to Richard Behringer?

We used a confocal laser scanning microscope.

Thank you!!

Whole‐Gut Spatial Genomic Analysis Reveals Molecular Regionalization of the Differentiating Zebrafish Enteric Nervous System Spatial genomic analysis of the developing enteric nervous system in zebrafish through multiplex whole mount HCR in slide identified genes that have temporal and spatial expression patterns during de...

We are leveraging this systems-level SGA to uncover unappreciated mechanistic insight at the cell and tissue levels into #ENS construction. Stay tuned for our work that exploits this pipeline within various mutant and perturbation conditions. Please reach out! 3/3 doi.org/10.1096/fj.2...

rounds of sequential #HCR and 3D imaging in zebrafish larvae to reveal spatial expression of numerous mRNAs in the same specimen. Data from these imaging data sets are then computationally analyzed for spatial cell groups, spatially variable genes, and differentially expressed genes along 3D 2/3

A sneak peak of a complex and technically challenging experiment that my lab developed: doi.org/10.1096/fj.2.... Super proud of PhD candidate Hannah Johnson for showcasing our Whole-gut spatial genomic analysis in #zebrafish. This video illustrates one landmark in the protocol after multiple 1/3

FYI: The switch to requiring the new NIH Biosketch format via SciENcv has been delayed until May. grants.nih.gov/grants/guide...

One of my favorite songs! 💕

Two ways to move together: Force coordination in collective chemotaxis Pacheco and Hutchins preview a new study from Diaz and Mayor, which reveals the distinct force-generating mechanisms used by epithelial and mesenchymal cel

Two ways to move together: Force coordination in collective chemotaxis url: rupress.org/jcb/article/...

Enhance your timeline on #InternationalDayOfWomenAndGirlsInScience by following our two(!) Starter Packs of outstanding Group Leaders and Senior Scientists from the #zebrafish community! 🐟 🧪

#WomenInScience Volume 1: go.bsky.app/4BegEjv
#WomenInScience Volume 2: go.bsky.app/VoebYrt

I will never understand how this is allowed to happen. There has to be a way to address this in a real way from NIH's end?

That's a great idea, Rachel.

That's interesting. What types of things are they doing to achieve those goals?

I know this may be played out by now, but I wanted to start a post (and hopefully get some real ideas) about what non-PI options there are out there for trainees considering careers after their PhDs. Especially now in 2026, after the hurricane we called 2025. They are anguished. Thanks, Everyone!

Building consensus: construction of a juvenile and adult scRNA-seq meta-atlas for dataset comparisons and harmonizing transcriptomic definitions of enteric neuron subtypes - BMC Genomics BMC Genomics - The enteric nervous system (ENS) is a complex network of interconnected ganglia within the gastrointestinal (GI) tract. Among its diverse functions, the ENS detects bowel luminal...

A new resource for the ENS community: link.springer.com/article/10.1...

Great news!

bsky.app/profile/klab...

I'm thrilled to see this beautiful work by recent Prince lab members Theresa Christiansen and Vish Venkataraman now in print! onlinelibrary.wiley.com/doi/epdf/10....