Vince Luca, PhD

The 2025-2026 BME TT Faculty jobs list has 125 positions. #FacultySearch #BME #BMEJobsList

Add a job: forms.gle/bwEzwHAEehBj...
Jobs list: ericaprattlab.com/bme_jobs_list/

2026 has been a remarkable year for me so far (despite the current world events): opening my lab at the University of Zurich, assembling an amazing group of people in the group, and celebrating it with a fantastic lab warming party. Figured it's also time for a small profile refresh.

Congrats!

Highly mutagenic continuous evolution in E. coli using a Φ29-based orthogonal replication system - Nature Biotechnology Mutational rates of bacterial evolution are increased using an error-prone orthogonal system.

Highly mutagenic continuous evolution in E. coli using a Φ29-based orthogonal replication system - @mrclmb.bsky.social go.nature.com/46rLLvX

Life Science Research Professional 1 in School of Medicine, Stanford, California, United States The Brunet lab in the Department of Genetics at Stanford University (https://web.stanford.edu/group/brunet/) is seeking an independent and motivated.....

Interested in the mechanisms of aging and 'rejuvenation'?

Our lab at Stanford has a Research Assistant/Lab manager position open!!

Apply and join our awesome team! 😎 (please share)

careersearch.stanford.edu/jobs/life-sc...

I am recruiting postdoctoral fellows to develop new research directions in the lab. We study transcriptional regulation through biomolecular condensates in development and disease, with an emphasis on first-principles and mechanistic discovery. Please repost or share with colleagues.

Thanks for sharing - I learned a lot from this!

I am looking for two postdocs to join our lab
- One (bio)image analyst
- One cell biologist interested to work on lymphatics!

The positions will open soon, be in touch!

Antibody-lectin chimeras for glyco-immune checkpoint blockade - Nature Biotechnology Cancer immunotherapy benefits from antibody-lectin chimeras that block glyco-immune checkpoints.

Antibody-lectin chimeras for glyco-immune checkpoint blockade - @jcstark.bsky.social @carolynbertozzi.bskyverified.social go.nature.com/4aRDpk8

I believe that we are about to see a major scientific conflict play out here on BlueSky, for better or for worse. I'll weigh in on this on the blog once I'm sure that I understand everyone's positions:

As I spent more and more of my life under the care of doctors, nurses, and researchers striving to improve the lives of others, I watched as Bobby cut nearly a half billion dollars for research into mRNA vaccines, technology that could be used against certain cancers; slashed billions in funding from the National Institutes of Health, the world's largest sponsor of medical research; and threatened to oust the panel of medical experts charged with recommending preventive cancer screenings. Hundreds of N.I.H. grants and clinical trials were cancelled, affecting thousands of patients. I worried about funding for leukemia and bone-marrow research at Memorial Sloan Kettering. I worried about the trials that were my only shot at remission. Early in my illness, when I

Just an absolutely gutting essay by Tatiana Schlossberg, a writer, mother of two young children, and cousin of RFK Jr who is dying of leukemia.

www.newyorker.com/culture/the-...

Scientific journals: we don’t want you using generative AI because it makes shit up.

Same journal: here is an AI summary or evaluation of this paper. This might be more useful than the actual abstract or paper that the authors freaking wrote

Same journal: AI cover art which makes no sense? Oooh!

This is a great idea!

Proteome-wide in silico screening for human protein-protein interactions Protein-protein interactions (PPIs) drive virtually all biological processes, yet most PPIs have not been identified and even more remain structurally unresolved. We developed a two-step computational...

Thrilled to share that the final piece of my PhD work is now on bioRxiv! biorxiv.org/content/10.1... With support from @nvidia and the @NSF, we used AlphaFold to screen 1.6M+ protein pairs, revealing thousands of potential novel PPIs. All data can be viewed at predictomes.org/hp

Biological Chemistry's position is still taking applications. UM is a great place to be a PI, I'd love to see a new membrane biology or lipids expert join our community.

This is open for new and established investigators.

@tombrettlab.bsky.social

Computrs usd a rstrictd alphabt to dsign protins that fold & “mak sns.”

Excited to share our new review on our current understanding of small cell lung cancer (SCLC) heterogeneity and plasticity, led by Gina Duronio in the lab: www.tandfonline.com/doi/full/10....

We are hiring an immunologist. This is a hard money position. We have a very robust research infrastructure. Rowan is rapidly growing, with 20,000+ undergrads, two med schools, and a vet school. Contact me for more details. jobs.rowan.edu/en-us/job/50...

This seems super relevant for TCR mimetic antibodies and pMHC minibinders…

A CRISPR activation screen reveals a cilia disassembly pathway mutated in focal cortical dysplasia A gain-of-function screen uncovers a cilia disassembly pathway linked to genes somatically mutated in neurodevelopmental disease.

Excited to share our latest work on a new cilia disassembly pathway and a link between this pathway and the neurological disorder focal cortical dysplasia: www.science.org/doi/10.1126/...
Brief summary: we used a genome-wide CRISPRa GOF screen to identify negative regulators of ciliary signaling...

ATTN: Two faculty positions are available in my department (neuroscience) at the University of Minnesota. This is a general search with no topic focus. November 20th application deadline.

Apply here: hr.umn.edu/jobs/Find-Job
Assistant Prof job code: 364920
Associate/Full Prof job code: 364921

This year’s Merck-Banyu Lectureship Award winner is Professor Koji Kubota from Hokkaido University. We are thrilled to welcome him to Stanford Chemistry on Thursday, October 23rd where he will give an exciting lecture on "Exploring Synthetic Mechanochemistry." chemistry.stanford.edu/events/merck...

Same here - maybe they are holding out hope for the shutdown to end so they can keep the panel on schedule. It doesn’t seem likely they could pull it off with this short notice, though.

For the #lovers of #TCRs -we are looking for #postdocs with interest in #functional and #mutational studies -dare to express 700 #self #antigen #specific #TCRs and #study them in #depth!!!!

Why does the naked mole rat have the longest lifespan of any rodent, nearly 40 years?
A 30-year long mystery unraveled @ScienceMagazine today!
Its cGAS enzyme in cells has 4 missense mutations that upends its function, promoting DNA repair and suppressing inflammation
www.science.org/doi/10.1126/...

If you’re around at the #NotchMeetingXIII poster session today, come by to check out Poster #9! 🧬✨
@anna_frontino will be there presenting our shared work on how Jagged1 variants shape liver vascular and biliary development.
Stop by to say hi and chat Notch!

CAR T therapy has seen great effectiveness in liquid tumors, but little in solid tumors (e.g. ovarian cancer).

Here we developed hyper-migratory CAR TV cells to infiltrate en masse ovarian tumors. (Left: control CAR T cells; right CAR TV cells).

Read this here: www.biorxiv.org/content/10.1...

Good luck - ridiculous situation!

I've been watching as NIGMS works their tails off to get R35 awards out the door before the end of the FY on 30 Sept. They all look great but this one really grabbed my attention.

It's about long "noncoding" (lnc) RNA's. Only, this one *does* encode peptides…

reporter.nih.gov/project-deta...