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sarthylab.bsky.social

@sarthylab

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Latest posts by sarthylab.bsky.social @sarthylab

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Given this is a Director's award, I'd be remiss to ignore the broader context of what the current NIH Director is presiding over right now at the NIH. These were my full thoughts when asked for a quote for this piece on what this means to me and our lab.

10.10.2025 18:15 👍 9 🔁 2 💬 0 📌 0

This work was spearheaded by Brittany Johnson, the very first Meers Lab member who has now moved on to a PhD at @ibisatnu.bsky.social, with big assists from Gabe Boyle and @sarthylab.bsky.social at Seattle Children's and David Spencer here at WashU. Hoping this is the first of many for the lab! 3/3

22.09.2025 16:38 👍 1 🔁 1 💬 2 📌 0

Congrats Meers Lab! Very important to develop an affordable, high-throughput version of CUT&Tag and have interesting findings in AML!

23.09.2025 02:01 👍 1 🔁 0 💬 0 📌 0
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Why does the government fund research at universities? : Planet Money American universities are where people go to learn and teach. They're also where research and development happens. Over the past eight decades, universities have received billions in federal dollars t...

Thank you @erikaberas.bsky.social for including me in this in depth @planetmoney.bsky.social piece on the mechanics of research funding at universities—I give it a 👍🏻👌👏👨‍🔬 emoji 🙃 www.npr.org/2025/05/28/1...

29.05.2025 01:05 👍 9 🔁 2 💬 0 📌 0

Please read our preprint: "G1 length dictates heterochromatin landscape"
www.biorxiv.org/content/10.1...

07.12.2023 18:27 👍 17 🔁 9 💬 0 📌 1
The cell-cycle choreography of H3 variants shapes the genome While the canonical core histones comprise typical nucleosomes, histone variants provide unique features linked to a variety of chromatin and DNA transactions. Delaney, Weiss, and Almouzni review the ...

Fantastic (& open access!) review by Delaney, Weiss, & Almouzni out this week in Mol Cell: www.cell.com/molecular-ce...; a timely synthesis covering everything you might want to know about dynamic H3 variant deposition and recycling, but were too afraid to ask 😄

21.09.2023 16:11 👍 1 🔁 1 💬 0 📌 0
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Chromatin Profiling of CBFA2T3-GLIS2 AMLs Identifies Key Transcription Factor Dependencies and BRG1 ... bioRxiv - the preprint server for biology, operated by Cold Spring Harbor Laboratory, a research and educational institution

Really excited to have contributed (in minor part) to this study from the
@SarthyLab
on chromatin vulnerabilities in CBFA2T3-GLIS2 AMLs. A clever synthesis of chromatin profiling, single-cell RNA, and DepMap data to uncover both mechanism and target 1/6 www.biorxiv.org/content/10.1...

06.09.2023 18:11 👍 5 🔁 3 💬 1 📌 0