Proud of the work accomplished as part of my PhD project and deeply grateful for the incredible collaboration behind it. This wouldn’t have been possible without the amazing team — huge thanks to everyone involved!
#WorldSickleCellDay #Gratitude #PhDJourney #SickleCellAwareness
What do long-range enhancers need to regulate genes? Researchers from the De Laat group have found that long-range enhancers require optimal regulatory protein levels, in addition to the specific protein complex cohesin, to switch on genes.
Read more here: www.hubrecht.eu/long-range-e...
Forced linear enhancer proximity can reactivate developmentally silenced globin genes in the β-globin and α-globin locus. This work assigns function to non-regulatory sequences in our genome and highlights the relevance of enhancer promoter distance. Del2Rec might offer therapeutic potential.
🚨 Preprint finally out! 🚨
Excited to share our latest work showing that linear enhancer-promoter distance matters! 🧬
Big thank you to all the co-authors and everyone who contributed! 🙌
Check it out here: www.biorxiv.org/content/10.1...
#Enhancers #GeneRegulation #Preprint
