Phoebe Oldach

does anyone have recommendations for super quick TAT high accuracy short read NGS data (ILL or very open to disruptors!) in Boston? Thank you!

Thank you, totally with you on that it should show distortion / error enough for a preliminary process check. I’ll let you know if there’s anything exciting to report :)

Thank you thank you!!! Did you have enough data to check for signal change from the biotin at all? (Trying to do a process check just on position of biotin incorp, so hoping I could be lazy use a pre-existing basecalling alg to call them as modified instead of having to generate training data!)

A computer screen with a display showing output from an xray diffraction spectrometer.

Close up view showing fraction of metals. Fun stuff.

Just had a sample of the Eaton Fire ash that is in my driveway run on the department XRF. Is there titanium (new house paint)? Yup. Lead (old house paint)? You betcha. Heavy metals? Check. Treat that ash like it's toxic folks (because it is)

🗻 Basecamp Research's Oliver Vince is headed to #Davos2025. This year’s #WEF theme, "Collaboration for the Intelligent Age," aligns with our mission to build a global network of biodiversity partnerships to train next-gen AI.

📅 Want to connect in Davos? Reach out at explore@basecamp-research.com.

Wow, very early! Thank you for sharing that

Detection of base analogs incorporated during DNA replication by nanopore sequencing Abstract. DNA synthesis is a fundamental requirement for cell proliferation and DNA repair, but no single method can identify the location, direction and s

has anyone run nanopore sequencing on biotinylated DNA? I have seen it in this paper but not since - would love to have a chat with anyone with experience! academic.oup.com/nar/article/...

🧬We're excited to share a series of announcements: John Finn has joined Basecamp Research as CSO, we've opened a US office and lab & we built one of Europe's largest industrial supercomputers with NVIDIA Accelerated Computing. Read Fierce Biotech's story here: www.fiercebiotech.com/research/com...
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The ribotoxic stress response drives acute inflammation, cell death, and epidermal thickening in UV-irradiated skin in vivo Solar UVB light causes damage to the outermost layer of skin. This insult induces rapid local responses, such as dermal inflammation, keratinocyte cel…

sunburn is from ribosomes stalled by UV damage to RNA? super cool www.sciencedirect.com/science/arti...

Advancement of openness requires consideration and integration with indigenous data sovereignty. See the Science piece and my conversation yesterday with Keolu Fox for advancements in this critical area for open science. www.youtube.com/watch?v=41Xa...

Basecamp Research Partners with Cameroon to Share Benefits from Genetic Data Use in Landmark Agreement

▶️ Basecamp Research’s new access and benefit-sharing partnership with the government of Cameroon includes a model for sharing data and resources to further research and protect local biodiversity: www.biopharmatrend.com/post/904-bas...

Though our work differs from Netflix, Basecamp Research shares one similarity: Our data is growing by an order of magnitude every year. As we build a digital twin of the natural world, our data expands exponentially. Read our CTO Phil Lorenz's insights in the FT's Sifted: sifted.eu/intelligence...

Leveraging genomes to support conservation and bioeconomy policies in a megadiverse country Vilaça et al. described a unique private-public initiative, the Genomics of the Brazilian Biodiversity (GBB) consortium. They outline the goals and challenges faced so far and discuss the gaps concern...

Leveraging genomes to support conservation and bioeconomy policies in a megadiverse country. #Genomics #BiodiversityConservation #GenomicsBrazilianBiodiversity #CellGenomics 🧬
www.cell.com/cell-genomic...

Sequence modeling and design from molecular to genome scale with Evo The genome is a sequence that encodes the DNA, RNA, and proteins that orchestrate an organism’s function. We present Evo, a long-context genomic foundation model with a frontier architecture trained o...

Real genotype-to-phenotype is now much closer in this beautiful work on a genomic foundation model from @brianhie.bsky.social. www.science.org/doi/10.1126/...

A groundbreaking new plan to get Big Pharma to pay for wildlife conservation Big companies use DNA from wild organisms to make money. This new plan aims to make them pay for it.

Thanks to vox for highlighting some of the COP16 discussions on how biotech valorizarion of digital sequence information can be shared back to biodiversity stakeholders - this is central to what we do at Basecamp.
www.vox.com/down-to-eart...

Microbial solutions must be deployed against climate catastrophe The climate crisis is escalating. A multitude of microbe-based solutions have been proposed (Table 1), and these technologies hold great promise and could

Some thoughts on this call to action:

I am very optimistic on future applications of industrial and environmental microbiology for environmental remediation and sustainable bioproduction - it's a big interest of mine! - but some caveats to be realistic about:
1/n

academic.oup.com/ismej/articl...

Bluesky for Science Bluesky starter packs for genomics, bioinformatics, R, and Nextflow

Bluesky for Science

Starter packs for genomics, bioinformatics, #Rstats, Nextflow. Moderation lists. Feeds. Let's rebuild the old scitwitter community and keep this place nice

blog.stephenturner.us/p/bluesky-fo... 🧬🖥️🧪