Amelia Eisch πŸ§ͺπŸ§ πŸ‘©β€πŸ”¬ 🐁's Avatar

Amelia Eisch πŸ§ͺπŸ§ πŸ‘©β€πŸ”¬ 🐁

@eisch

Philadelphia Neuroscience Professor obsessed w/dentate gyrus, mentoring, unsweet soymilk. Opinions & bad jokes are mine not my employer’s. She/her/cat. https://sites.google.com/view/eischlab Pics: 75% my smiling face, desk, laptop, blue sky with clouds

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Latest posts by Amelia Eisch πŸ§ͺπŸ§ πŸ‘©β€πŸ”¬ 🐁 @eisch

Tomorrow at @sfn.org Meet-the-Expert webinar seriesπŸ‘‡πŸΌ

10.03.2026 07:34 πŸ‘ 8 πŸ” 1 πŸ’¬ 0 πŸ“Œ 0

i was gonna joke "a hero to most, but he never meant shit to me" but then i realized a bunch of those kids might not know who Public Enemy is either

10.03.2026 00:02 πŸ‘ 278 πŸ” 35 πŸ’¬ 19 πŸ“Œ 0
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Why Missouri Prisons Can Be Deadly for People With Opioid Addictions In a prison system rife with drugs, a new civil rights lawsuit accuses the Missouri DOC of punishing people for addiction, rather than treating it.

There is no excuse for denying people lifesaving care and punishing them for addiction.

It's not just horrific β€” it's unconstitutional and discriminatory.

09.03.2026 20:49 πŸ‘ 168 πŸ” 53 πŸ’¬ 3 πŸ“Œ 2
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NASA administrator talks to Science about studying the Moon, Marsβ€”and Earth Jared Isaacman says agency may accelerate lunar science program and could tackle a new Mars mission in 2028

My latest: in an interview with @science.org, new NASA administrator Jared Isaacman promises a big uptick in lunar robotic missions, another potential Mars 2028 mission beyond comms, and continued support for earth science observation.

(Sorry astro and helio folks, time went fast.)

09.03.2026 20:21 πŸ‘ 20 πŸ” 10 πŸ’¬ 3 πŸ“Œ 2

Check out our latest research drop! We show BLA dopamine signaling encodes the emotional weight of sensory transitions, but not the associative strength or value of stimuli. These signals dynamically rescale when the learning context changes: "this matters most!" www.biorxiv.org/content/10.1...

09.03.2026 15:06 πŸ‘ 58 πŸ” 25 πŸ’¬ 3 πŸ“Œ 0
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a cartoon says hey everybody an old man 's talking while bart simpson looks on ALT: a cartoon says hey everybody an old man 's talking while bart simpson looks on

A short Bluetorial on plots of NIH application success rates as a function of percentile.

1/20

09.03.2026 14:56 πŸ‘ 110 πŸ” 52 πŸ’¬ 1 πŸ“Œ 4
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Dissertation Defense Tomorrow Morning at 9 AM.
Characterizing the neurobiology of cocaine choice in rats: behavioral, pharmacological, and cellular contributions #mcwpharmtox #pharmlife2026

09.03.2026 15:04 πŸ‘ 2 πŸ” 2 πŸ’¬ 0 πŸ“Œ 0

Temporally-precise sensory encoding of predicted content, entraining motor oscillations to derive time. @akalt.bsky.social's first study out @currentbiology.bsky.social, testing parts of this idea (tinyurl.com/TiCSKaltenma...). Huge thanks @leverhulme.ac.uk ac.uk @erc.europa.eu, great work Aaron!

09.03.2026 10:19 πŸ‘ 34 πŸ” 13 πŸ’¬ 0 πŸ“Œ 0
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Even Philly’s crosswalks have hoagiemouth. We found out why for youse. β€œIt feels like one of those many only-in-Philly things, of course even our crosswalks have a thick Philly accent.”

ICYMI over the weekend, I looked into why some of Philadelphia's Audible Pedestrian Signal systems at city crosswalks come wit the Philly accent.

www.inquirer.com/columnists/i...

09.03.2026 14:07 πŸ‘ 17 πŸ” 4 πŸ’¬ 1 πŸ“Œ 1
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NIH FY2025 funding data finally emerges on RePORT The FY2025 funding picture was disrupted significantly by the mandate for Multi-Year Funding of about half of the budget for extramural awards. This produced a mid-year declaration by NCI that thei…

NIH FY2025 funding data finally emerges on RePORT drugmonkey.wordpress.com/2026/03/06/n...

09.03.2026 14:12 πŸ‘ 1 πŸ” 1 πŸ’¬ 0 πŸ“Œ 0

In animals with large genomes, finding cis-regulatory elements can be very challenging. Enhancers can be located tens/hundreds of kb away from their target promoters. We face this challenge in Parhyale, with >3 Gbp genome.
We just published a preprint describing how we are tackling this problem. /1

09.03.2026 09:38 πŸ‘ 42 πŸ” 19 πŸ’¬ 4 πŸ“Œ 0

Longer dive into the data, meaning, and consequences

substack.com/home/post/p-...

08.03.2026 21:11 πŸ‘ 20 πŸ” 10 πŸ’¬ 0 πŸ“Œ 2
Vivid pink sky from second floor window looking west

Vivid pink sky from second floor window looking west

Lookin good West Philly sunset

08.03.2026 23:18 πŸ‘ 28 πŸ” 1 πŸ’¬ 0 πŸ“Œ 1
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Painted in 2015, you can find β€œStart From Here” by Isaac Lin on Race Street between 13th and Broad!

(References: To be as accurate about this artwork as possible, some portions of this script were written using copy from this muralβ€˜s project page.)

08.03.2026 23:34 πŸ‘ 60 πŸ” 10 πŸ’¬ 3 πŸ“Œ 0

🌿 Postdoc opportunity in plant evolutionary ecology/genetics!

My lab in the Dept. of Ecology & Evolutionary Biology at the University of Michigan is recruiting a postdoctoral researcher to start Fall 2026.

We study plant adaptation, using weeds as model systems.

#Postdoc #EcoEvo

Pls RT!

08.03.2026 21:27 πŸ‘ 110 πŸ” 150 πŸ’¬ 2 πŸ“Œ 0
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I just reviewed an unbelievably cool grant proposal, like, to the point that I was practically reaching for my wallet and mailing them cash

next time you write a grant, consider making it unbelievably cool

09.10.2023 02:09 πŸ‘ 63 πŸ” 5 πŸ’¬ 0 πŸ“Œ 3
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Collective dynamical regimes predict invasion success and impacts in microbial communities - Nature Ecology & Evolution Predicting invasion outcomes in microbial communities is challenging. Here the authors demonstrate that these outcomes in both theoretical and experimental microbial communities can be predicted based...

Incredible! The ultimate experiment. If we could only do something like this for brains, it would go *so far* toward understanding brain and mental conditions.

www.nature.com/articles/s41...

08.03.2026 13:15 πŸ‘ 27 πŸ” 8 πŸ’¬ 2 πŸ“Œ 0
A Day in the Life of an Ensh*ttificator
A Day in the Life of an Ensh*ttificator YouTube video by ForbrukerrΓ₯det - Norwegian Consumer Council

The Norwegian Consumer Council with an amazing video on enshittification and how to resist it.

www.youtube.com/watch?v=T4Up...

08.03.2026 10:27 πŸ‘ 106 πŸ” 47 πŸ’¬ 3 πŸ“Œ 13
A detailed digital composite image based on the 1947 historical photograph of geneticist Barbara McClintock. McClintock, with her characteristic short hair and round glasses, is seated at a microscope, using tweezers in a Petri dish. While based on the original photo distributed for her AAUW award, this image presents a significantly expanded and fictionalized laboratory environment. The simple wooden workbench is now densely populated with a vast, colorized collection of complex glassware, numerous amber-colored reagent bottles, intricate distillation columns, and botanical specimens relevant to maize cytogenetics, creating a rich, illustrative narrative of her "jumping gene" research context that was not present in the original photo. The expanded background shows complex vintage laboratory cabinetry. This image explicitly states it is a composite: a digital recreation where Seriously Scientific has taken the historical figure and placed them into an augmented, complex fictionalized environment. Based on original source from Smithsonian Institution Archives. Digital composite by Seriously Scientific.

A detailed digital composite image based on the 1947 historical photograph of geneticist Barbara McClintock. McClintock, with her characteristic short hair and round glasses, is seated at a microscope, using tweezers in a Petri dish. While based on the original photo distributed for her AAUW award, this image presents a significantly expanded and fictionalized laboratory environment. The simple wooden workbench is now densely populated with a vast, colorized collection of complex glassware, numerous amber-colored reagent bottles, intricate distillation columns, and botanical specimens relevant to maize cytogenetics, creating a rich, illustrative narrative of her "jumping gene" research context that was not present in the original photo. The expanded background shows complex vintage laboratory cabinetry. This image explicitly states it is a composite: a digital recreation where Seriously Scientific has taken the historical figure and placed them into an augmented, complex fictionalized environment. Based on original source from Smithsonian Institution Archives. Digital composite by Seriously Scientific.

Remembering Barbara McClintock on International Women's Day!
She discovered that genes aren't static, they can actually "jump" around on a chromosome.

Her discovery of transposons ("jumping genes") fundamentally changed how we understand evolution and the complexity of DNA! 🧬🌽

#WomenInScience

08.03.2026 12:24 πŸ‘ 563 πŸ” 162 πŸ’¬ 6 πŸ“Œ 3
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Stand Up for Science at Philadelphia, the original American city of science. #standupforscience # Philadelphia

08.03.2026 13:39 πŸ‘ 152 πŸ” 24 πŸ’¬ 1 πŸ“Œ 0
Dr. Jeremy Berg speaking in front of a crowd at Pittsburgh Stand Up for Science.

Dr. Jeremy Berg speaking in front of a crowd at Pittsburgh Stand Up for Science.

It’s @jeremymberg.bsky.social talking at Pittsburgh Stand Up For Science. #StandUpforScience

07.03.2026 19:01 πŸ‘ 73 πŸ” 11 πŸ’¬ 4 πŸ“Œ 0
Graph of award probability of R35 and R01 from NIH factbook as a function of review rank percentile. As is apparent, 2025 is a significant departure, with lower award probabilities at all scores <40 and significant departures from norm, where even being in the top 10% is no longer a nearly certain indicator of success.

Data source: https://report.nih.gov/nihdatabook/report/302

Graph of award probability of R35 and R01 from NIH factbook as a function of review rank percentile. As is apparent, 2025 is a significant departure, with lower award probabilities at all scores <40 and significant departures from norm, where even being in the top 10% is no longer a nearly certain indicator of success. Data source: https://report.nih.gov/nihdatabook/report/302

The data is in: the NIH goalposts have shifted.

What were once almost certain fundable scores have become coin flips and what used to be likely grants have become aspirational, leading to fewer awards.

Another manifestation of how HHS policies have led to fewer awards and less science.

07.03.2026 01:59 πŸ‘ 680 πŸ” 415 πŸ’¬ 19 πŸ“Œ 61
Job Opening: Data Scientist – Grant Witness Grant Witness seeks a data scientist for a full-time position on our team tracking changes to U.S. federal grantmaking. We are also hiring for part-time/contract positions. Join us!

Grant Witness is hiring! We're seeking a full-time data scientist to join our team building data resources to support journalism, litigation, and activism protecting science, public health, and the rule of law. grant-witness.us/apply.html #rstats

06.03.2026 21:14 πŸ‘ 115 πŸ” 82 πŸ’¬ 1 πŸ“Œ 7
STAND UP FOR SCIENCE ANNOUNCES MRS. FRAZZLED, INFLUENCER AND PUBLIC EDUCATION ADVOCATE AS A SPEAKER AT THE VIRTUAL NATIONAL DAY OF ACTION RALLY (tr.ee/virtual-rally)
MARCH 7TH, 2026 NATIONWIDE
*Stand Up for Science* logo
Join the fight at standupforscience.net

STAND UP FOR SCIENCE ANNOUNCES MRS. FRAZZLED, INFLUENCER AND PUBLIC EDUCATION ADVOCATE AS A SPEAKER AT THE VIRTUAL NATIONAL DAY OF ACTION RALLY (tr.ee/virtual-rally) MARCH 7TH, 2026 NATIONWIDE *Stand Up for Science* logo Join the fight at standupforscience.net

Stand Up For Science announces Mrs. Frazzled (@mrs-frazzled.bsky.social) as a speaker at the Virtual National Day of Action rally on Saturday, March 7th!

(tr.ee/virtual-rally)

Visit standupforscience.net/march7 to find local rally!

#standupforscience
#March7Virtual
#science
#rally
#savescience

07.03.2026 01:16 πŸ‘ 74 πŸ” 16 πŸ’¬ 0 πŸ“Œ 0
On the right side of the photo in white text reads: "STAND UP FOR SCIENCE ANNOUNCES DR. AKILAH CADET, HUMAN RIGHTS ACTIVIST AS A SPEAKER AT THE VIRTUAL NATIONAL DAY OF ACTION RALLY (tr.ee/virtual-rally) MARCH 7TH, 2026 NATIONWIDE". Below that is the "STAND UP FOR SCIENCE" logo. Below that in white text reads: "Join the fight at standupforscience.net". To the left side of that is a photo of Dr. Akilah Cadet wearing a shirt that says "KEEP BEING AMAZING".

On the right side of the photo in white text reads: "STAND UP FOR SCIENCE ANNOUNCES DR. AKILAH CADET, HUMAN RIGHTS ACTIVIST AS A SPEAKER AT THE VIRTUAL NATIONAL DAY OF ACTION RALLY (tr.ee/virtual-rally) MARCH 7TH, 2026 NATIONWIDE". Below that is the "STAND UP FOR SCIENCE" logo. Below that in white text reads: "Join the fight at standupforscience.net". To the left side of that is a photo of Dr. Akilah Cadet wearing a shirt that says "KEEP BEING AMAZING".

Stand Up for Science announces Dr. Akilah Cadet, Human Rights Activist as a speaker at the VIRTUAL National Day of Action Rally (tr.ee/virtual-rally), on March 7th 2026, Nationwide.

Join the fight at standupforscience.net/march7

#March7
#standupforscience
#science
#savescience
#rally

07.03.2026 01:30 πŸ‘ 35 πŸ” 13 πŸ’¬ 0 πŸ“Œ 0
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Undergraduate students from the #Jadavjilab presented today at the @genetics-gsa.bsky.social #Dros26. I am a #proudPI!

07.03.2026 01:30 πŸ‘ 6 πŸ” 2 πŸ’¬ 0 πŸ“Œ 0
A 1944 map by geologist Harold Fisk charts a 40-mile stretch of the Mississippi River from Friars Point to Gunnison, Mississippi. Fisk used aerial photos and maps to estimate the past and then-present channels. Source: https://www.nationalgeographic.com/science/article/mississippi-rivers-hidden-history-uncovered-by-lidar?fbclid=IwY2xjawQYXkdleHRuA2FlbQIxMABicmlkETFCZ2JBT2tWdVlXMmEzNU5Uc3J0YwZhcHBfaWQQMjIyMDM5MTc4ODIwMDg5MgABHsbjW-Yuubr_o_Kfeh0Elzc94geDwfXIZmeNL7NyljEBAOEjH53m2QLSo1NF_aem__4NkCIJ_D8J6mI1e8eMByg

A 1944 map by geologist Harold Fisk charts a 40-mile stretch of the Mississippi River from Friars Point to Gunnison, Mississippi. Fisk used aerial photos and maps to estimate the past and then-present channels. Source: https://www.nationalgeographic.com/science/article/mississippi-rivers-hidden-history-uncovered-by-lidar?fbclid=IwY2xjawQYXkdleHRuA2FlbQIxMABicmlkETFCZ2JBT2tWdVlXMmEzNU5Uc3J0YwZhcHBfaWQQMjIyMDM5MTc4ODIwMDg5MgABHsbjW-Yuubr_o_Kfeh0Elzc94geDwfXIZmeNL7NyljEBAOEjH53m2QLSo1NF_aem__4NkCIJ_D8J6mI1e8eMByg

Rivers are living beings.

07.03.2026 01:31 πŸ‘ 2400 πŸ” 605 πŸ’¬ 40 πŸ“Œ 73

Wow this visual is so striking… in a bad wayπŸ™ƒ

07.03.2026 01:36 πŸ‘ 1 πŸ” 1 πŸ’¬ 1 πŸ“Œ 0
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Habit and hard hat: the unconventional practice of Sister Nesta Fitzgerald-Lombard at St Leonards Mayfield, 1954–1994 This article analyses the career of the nun and architect Nesta Fitzgerald-Lombard (1916–2006) to argue for greater recognition of the unconventional career paths of women architects. Among the fir...

πŸŽ‰ Just published: my article on nun-architect Sister Nesta Fitzgerald-Lombard and the need to expand perceptions of architectural labour to include women who have followed unconventional paths to practice. Open Access in @thejoa.bsky.social doi.org/10.1080/1360...

21.01.2026 16:16 πŸ‘ 20 πŸ” 4 πŸ’¬ 1 πŸ“Œ 1

The Grosshans lab and their collaborators are using DNA-paint to visualize the protein complexes that mediate cell adhesion during embryonic morphogenesis at unprecedented resolution--check it out! πŸ§ͺ

06.03.2026 11:36 πŸ‘ 12 πŸ” 1 πŸ’¬ 0 πŸ“Œ 0