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Therapeutic Advances in Neurological Disorders

@taneuroldisord

A leading gold #OpenAccess journal in clinical neurology | IF 4.1 CiteScore 8.5 | 🧠 Follow us for neurological research and news.

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27.03.2025
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Latest posts by Therapeutic Advances in Neurological Disorders @taneuroldisord

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New research online!

Tremor monitoring by a tri-axis accelerometer can help assess the efficacy of magnetic resonance-guided focused ultrasound (MRgFUS) thalamotomy in patients with #EssentialTremor:
journals.sagepub.com/doi/full/10....

13.03.2026 12:09 πŸ‘ 0 πŸ” 1 πŸ’¬ 0 πŸ“Œ 0
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Platelet inhibition strategies in rescue stenting after failed thrombectomy for #stroke: results from a large retrospective cohort study involving 34 international centers:
journals.sagepub.com/doi/10.1177/...

12.03.2026 15:57 πŸ‘ 0 πŸ” 0 πŸ’¬ 0 πŸ“Œ 0
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Aspiration, stent retriever, or combined approach for basilar artery occlusion?
Check out this three-way comparative analysis of prospective data from 500+ patients with #stroke:
journals.sagepub.com/doi/full/10....

12.03.2026 13:54 πŸ‘ 3 πŸ” 1 πŸ’¬ 1 πŸ“Œ 0
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New Review online!

What are the modifiable risk factors for #MultipleSclerosis comorbidities?

Find out more here:
journals.sagepub.com/doi/full/10....

11.03.2026 16:01 πŸ‘ 1 πŸ” 1 πŸ’¬ 0 πŸ“Œ 0
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Does resting heart rate have prognostic significance for endovascular treatment outcomes in acute ischemic #stroke with large vessel occlusion?
πŸ«€Lu Zhang and colleagues investigated:
journals.sagepub.com/doi/full/10....

10.03.2026 10:27 πŸ‘ 1 πŸ” 1 πŸ’¬ 0 πŸ“Œ 0
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Drug breakthrough for children with rare form of extreme epilepsy Families say the groundbreaking medicine is transforming the lives of children with Dravet syndrome.

Promising results of reduced #seizure frequency from early-phase trials of the antisense oligonucleotide #zorevunersen, administered via a spinal infusion in children with #Dravet syndrome:
www.bbc.co.uk/news/article...

05.03.2026 17:40 πŸ‘ 2 πŸ” 1 πŸ’¬ 0 πŸ“Œ 0
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How does #cladribine treatment affect disease activity in people with highly active #MultipleSclerosis?

Klaus Schmierer and colleagues provide the 2-year results from the MAGNIFY-MS Study:
journals.sagepub.com/doi/10.1177/...

05.03.2026 17:33 πŸ‘ 1 πŸ” 0 πŸ’¬ 0 πŸ“Œ 0
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πŸ“°New Review online on Hereditary Spastic Paraplegia:

🧬Understanding the specific genetic changes and advances in medical technology have enabled targeted and personalized treatments, including #GeneTherapy, repurposed drugs, and digital health tools:
journals.sagepub.com/doi/full/10....

04.03.2026 11:59 πŸ‘ 1 πŸ” 1 πŸ’¬ 0 πŸ“Œ 0
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New Plain Language Summary of a Publication online!
This #accessibleresearch summary explains the results from a Phase2b RCT and its open-label extension that looked at the safety and effects of #ecopipam in children and adolescents with #Tourette syndrome:
journals.sagepub.com/doi/epdf/10....
#PLSP

03.03.2026 11:14 πŸ‘ 1 πŸ” 1 πŸ’¬ 0 πŸ“Œ 0
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πŸ“ New Review online in our Special Collection on CAR T-cells in Autoimmune Neurological Disorders:

What is the role of neuroimaging in diagnosis and management of neurotoxicity in patients treated by CAR T-cell therapy?

Arian Lasocki and colleagues discuss:
journals.sagepub.com/doi/full/10....

02.03.2026 12:30 πŸ‘ 1 πŸ” 1 πŸ’¬ 0 πŸ“Œ 0
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Comprehensive versus thrombectomy-capable stroke centers: a web-based model to predict outcomes after mechanical thrombectomy - Shujuan Gan, Weifeng Huang, Tingyu Yi, Wenli Zhang, Xiongwei Lu, Zhiting... Background: The quality and clinical outcomes of mechanical thrombectomy (MT) performed at thrombectomy-capable stroke centers (TSCs) versus comprehensive strok...

New research online!
When patients undergo mechanical thrombectomy, does being treated in a thrombectomy-capable versus comprehensive #stroke center affect the outcomes?
Find out more here: journals.sagepub.com/doi/full/10....

27.02.2026 11:22 πŸ‘ 1 πŸ” 1 πŸ’¬ 0 πŸ“Œ 0
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What kind of clinical factors affect the short- and long-term prognosis in late-onset #MyastheniaGravis?
journals.sagepub.com/doi/10.1177/...

26.02.2026 09:26 πŸ‘ 0 πŸ” 0 πŸ’¬ 0 πŸ“Œ 0
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πŸ“„New research online!

πŸ’ŠWhat is the real-world effectiveness of #cladribine tablets in people with #MultipleSclerosis?

πŸ‘¨β€βš•οΈMatteo Lucchini and colleagues analyzed data from multiple centers in Italy:
journals.sagepub.com/doi/full/10....

26.02.2026 09:16 πŸ‘ 2 πŸ” 1 πŸ’¬ 0 πŸ“Œ 0
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New online!
Here, Bhupendra Khatri and colleagues discuss their experiences in therapeutic plasma exchange in autoimmune neurological disorders: journals.sagepub.com/doi/full/10....

24.02.2026 11:57 πŸ‘ 2 πŸ” 1 πŸ’¬ 0 πŸ“Œ 0
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New research online! πŸ“°
Is horizontal switching a valid #MultipleSclerosis treatment strategy?

Enrique Gomez-Figueroa and colleagues analyzed the MSBase Registry to find out the real-world effectiveness of horizontal switching between disease-modifying therapies:
journals.sagepub.com/doi/full/10....

23.02.2026 12:01 πŸ‘ 1 πŸ” 1 πŸ’¬ 0 πŸ“Œ 0
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This #SystematicReview and Meta-analysis compared efficacy and safety of combining #bevacizumab with re-irradiation versus bevacizumab alone in recurrent high-grade #glioma:
journals.sagepub.com/doi/full/10....

20.02.2026 10:59 πŸ‘ 0 πŸ” 0 πŸ’¬ 0 πŸ“Œ 0
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Sage Journals: Discover world-class research Subscription and open access journals from Sage, the world's leading independent academic publisher.

New online!
This large (>20000 patients) cohort study on secondary #stroke prevention describes the challenges in adherence to secondary stroke prevention medication in China:
journals.sagepub.com/doi/full/10....
#MedSky #NeuroSky

20.02.2026 10:19 πŸ‘ 1 πŸ” 1 πŸ’¬ 0 πŸ“Œ 0
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πŸ“ New #SystematicReview & Meta-Analysis online!

🧠 What is the safety and efficacy of initiating oral anticoagulants versus avoiding anticoagulation in adults with #AFib after spontaneous intracranial hemorrhage?

πŸ—‚οΈ This article draws evidence from #stroke RCTs:
journals.sagepub.com/doi/full/10....

17.02.2026 13:44 πŸ‘ 1 πŸ” 1 πŸ’¬ 0 πŸ“Œ 0
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Regional perfusion parameters as potential indicators of parenchymal hematoma risk following reperfusion therapy for acute ischemic stroke in the extended time window - Xinyu Liu, Lan Hong, Guangjian ... Background: Parenchymal hematoma (PH) is a common complication of acute ischemic stroke, particularly following reperfusion therapy. Objective: This study aime...

New article out in our Special Collection on Acute Reperfusion Therapies for Acute Ischemic Stroke:

Is there a relationship between regional perfusion parameters and parenchymal hematoma outcomes in #stroke patients treated in the extended time window?
journals.sagepub.com/doi/full/10....

16.02.2026 10:55 πŸ‘ 1 πŸ” 2 πŸ’¬ 0 πŸ“Œ 0
Preview
Sage Journals: Discover world-class research Subscription and open access journals from Sage, the world's leading independent academic publisher.

A Systematic Review & Meta-Analysis:
Risk of #stroke in patients with #MultipleSclerosis who receive disease-modifying treatments:
journals.sagepub.com/doi/10.1177/...

10.02.2026 19:37 πŸ‘ 0 πŸ” 0 πŸ’¬ 0 πŸ“Œ 0
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Is intravenous immunoglobulin (IVIG) therapy effective in chronic inflammatory demyelinating polyradiculoneuropathy (CIDP) patients with #diabetes mellitus?

Check out this new prospective study by Samir Macwan and colleagues to find out more:
journals.sagepub.com/doi/full/10....

10.02.2026 11:12 πŸ‘ 2 πŸ” 1 πŸ’¬ 0 πŸ“Œ 0
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New research online!
What is the real-world effectiveness and tolerability of #lasmiditan in the acute treatment of #migraine?

journals.sagepub.com/doi/full/10....

09.02.2026 15:01 πŸ‘ 1 πŸ” 1 πŸ’¬ 0 πŸ“Œ 0
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New Case Report online!
Spinocerebellar ataxia type 3 (SCA3) masquerading as atypical parkinsonism?
πŸ”ŽThe findings underscore the importance of genetic testing in atypical parkinsonism and the need for personalized deep-brain stimulation strategies in SCA3.
journals.sagepub.com/doi/full/10....

06.02.2026 13:38 πŸ‘ 1 πŸ” 1 πŸ’¬ 0 πŸ“Œ 0
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New international Delphi consensus clarifies best practices for steroid use in generalized #MyastheniaGravis:

Key takeaways:
πŸ‘‰Aim ≀5 mg/day long‑term
πŸ‘‰Prioritize biologics to reduce OCS burden
πŸ‘‰Individualize tapering strategies
journals.sagepub.com/doi/full/10....

05.02.2026 10:00 πŸ‘ 2 πŸ” 1 πŸ’¬ 0 πŸ“Œ 0
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Novel data on interplay between dimethyl fumarate, gut microbiota and clinical response to treatment in #MultipleSclerosis:
journals.sagepub.com/doi/10.1177/...

05.02.2026 09:51 πŸ‘ 1 πŸ” 0 πŸ’¬ 0 πŸ“Œ 0
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Rethinking the gut-brain axis in #MultipleSclerosis:
πŸ‘‰ Short-chain fatty acid decline could reflect disease progression, not the initial demyelinating event
πŸ”ŽData needed to track microbiome changes across MS trajectories and under different immunotherapies
journals.sagepub.com/doi/full/10....

04.02.2026 11:11 πŸ‘ 2 πŸ” 2 πŸ’¬ 1 πŸ“Œ 0
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Important German consensus paper on vaccination strategies in people with autoimmune neurological disorders:

Recommendations are provided on types and timing of vaccinations and ways to optimize immunization in people on different immunotherapies.
journals.sagepub.com/doi/full/10....

03.02.2026 10:29 πŸ‘ 1 πŸ” 1 πŸ’¬ 0 πŸ“Œ 0
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New important data for managing rare post-transplant neuropathies in TAND:
Patisiran shows promise for acquired amyloid polyneuropathy in domino liver transplant recipientsβ€”improved NIS scores over 22 months with no major renal, cardiac, or immunologic adverse effects.
πŸ”— doi.org/10.1177/1756...

02.02.2026 17:40 πŸ‘ 1 πŸ” 1 πŸ’¬ 0 πŸ“Œ 0
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Another new article in our Special Collection on CAR T-cells in Autoimmune Neurological Disorders!

This Review discusses the scientific rationale for repurposing CAR T-cells for neurological disorders, and provides an update on therapies in the pipeline:
journals.sagepub.com/doi/full/10....

30.01.2026 16:18 πŸ‘ 2 πŸ” 1 πŸ’¬ 0 πŸ“Œ 1
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Massimo Cesareo and colleagues used OCT imaging to evaluate the impact of anti-CGRP monoclonal antibodies on retinal features in patients with #migraine: journals.sagepub.com/doi/10.1177/...

29.01.2026 14:31 πŸ‘ 0 πŸ” 0 πŸ’¬ 0 πŸ“Œ 0