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Johannes Kappel

@johanneskappel

Neuroscientist, working on connectomics & cognition. EMBO Postdoctoral Fellow @ FMI Basel πŸ‡¨πŸ‡­

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16.11.2024
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Latest posts by Johannes Kappel @johanneskappel

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First whole-brain recording of social sound processing in a vertebrate. Surprises start in the hindbrain; thalamus gates conspecific calls; male and female brains diverge downstream. Work by @joerghenninger.bsky.social, @mh123.bsky.social sky.social and team. www.biorxiv.org/content/10.6...

05.03.2026 09:47 πŸ‘ 116 πŸ” 46 πŸ’¬ 7 πŸ“Œ 4

Exciting! Looking forward to reading πŸ™‚

05.03.2026 20:02 πŸ‘ 1 πŸ” 0 πŸ’¬ 0 πŸ“Œ 0

This is a very important story. Thank you @science.org for covering it.

Two critical points: 1. SIMPLE INVESTIGATION! 2. Notice how not being desperate for money leads people to use good judgement? This is why philanthropy isn't going to fix what Trump has done to our scientific ecosystem.

03.03.2026 16:45 πŸ‘ 48 πŸ” 21 πŸ’¬ 0 πŸ“Œ 1

I have a male friend who spent some time in Axel's lab. About the 3rd conversation he had with Axel, Axel broke the ice with "So, have you fucked [a female postdoc in the lab] yet?"

My friend was horrified...

26.02.2026 12:43 πŸ‘ 200 πŸ” 70 πŸ’¬ 12 πŸ“Œ 8
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Leader of Columbia Brain Institute Quits Over Friendship With Epstein

Breaking:

Richard Axel, a Nobel Prize-winning scientist and professor, just announced that he was resigning as a co-director of a flagship neuroscience institute at Columbia University because of his friendship with Jeffery Epstein.
www.nytimes.com/2026/02/25/n...

25.02.2026 06:30 πŸ‘ 2954 πŸ” 1066 πŸ’¬ 153 πŸ“Œ 109
The political effects of X's feed algorithm
https://doi.org/10.1038/s41586-026-10098-2
Received: 16 December 2024
Accepted: 4 January 2026
Published online: 18 February 2026
Open access
β€’ Check for updates
Germain Gauthier,5, Roland Hodler?5, Philine Widmer35 & Ekaterina Zhuravskaya3,4,5 m
Feed algorithms are widely suspected to influence political attitudes. However, previous evidence from switching off the algorithm on Meta platforms found no political effects'. Here we present results from a 2023 field experiment on Elon Musk's platform X shedding light on this puzzle. We assigned active US-based users randomly to either an algorithmic or a chronological feed for 7 weeks, measuring political attitudes and online behaviour. Switching from a chronological to an algorithmic feed increased engagement and shifted political opinion towards more conservative positions, particularly regarding policy priorities, perceptions of criminal investigations into Donald Trump and views on the war in Ukraine. In contrast, switching from the algorithmic to the chronological feed had no comparable effects.
Neither switching the algorithm on nor switching it off significantly affected affective polarization or self-reported partisanship. To investigate the mechanism, we analysed users' feed content and behaviour. We found that the algorithm promotes conservative content and demotes posts by traditional media. Exposure to algorithmic content leads users to follow conservative political activist accounts, which they continue to follow even after switching off the algorithm, helping explain the asymmetry in effects. These results suggest that initial exposure to X's algorithm has persistent effects on users' current political attitudes and account-following behaviour, even in the absence of a detectable effect on partisanship.

The political effects of X's feed algorithm https://doi.org/10.1038/s41586-026-10098-2 Received: 16 December 2024 Accepted: 4 January 2026 Published online: 18 February 2026 Open access β€’ Check for updates Germain Gauthier,5, Roland Hodler?5, Philine Widmer35 & Ekaterina Zhuravskaya3,4,5 m Feed algorithms are widely suspected to influence political attitudes. However, previous evidence from switching off the algorithm on Meta platforms found no political effects'. Here we present results from a 2023 field experiment on Elon Musk's platform X shedding light on this puzzle. We assigned active US-based users randomly to either an algorithmic or a chronological feed for 7 weeks, measuring political attitudes and online behaviour. Switching from a chronological to an algorithmic feed increased engagement and shifted political opinion towards more conservative positions, particularly regarding policy priorities, perceptions of criminal investigations into Donald Trump and views on the war in Ukraine. In contrast, switching from the algorithmic to the chronological feed had no comparable effects. Neither switching the algorithm on nor switching it off significantly affected affective polarization or self-reported partisanship. To investigate the mechanism, we analysed users' feed content and behaviour. We found that the algorithm promotes conservative content and demotes posts by traditional media. Exposure to algorithmic content leads users to follow conservative political activist accounts, which they continue to follow even after switching off the algorithm, helping explain the asymmetry in effects. These results suggest that initial exposure to X's algorithm has persistent effects on users' current political attitudes and account-following behaviour, even in the absence of a detectable effect on partisanship.

A new paper shows that less than 2 months of exposure to Twitter’s algorithmic feed significantly shifts people’s political views to the right.

Moving from chronological feed to the algorithmic feed also increases engagement.

This is one of the most concerning papers I’ve read in awhile.

19.02.2026 18:57 πŸ‘ 6451 πŸ” 3222 πŸ’¬ 158 πŸ“Œ 405
Mia Valentina Paz Faria
A 7-year-old from Venezuela who was living in Austin, Texas 
Detained for 70 days

β€œI don’t want to be in this place I want to go to my school.”

Mia Valentina Paz Faria A 7-year-old from Venezuela who was living in Austin, Texas Detained for 70 days β€œI don’t want to be in this place I want to go to my school.”

UPDATE: Staff at the ICE concentration camp in Dilley, Texas have begun raiding the dormitories of kids and their parents to confiscate and destroy letters from the children. This is in response to the ace reporting by 
@micarosenberg
 et al for ProPublica:

UPDATE: Staff at the ICE concentration camp in Dilley, Texas have begun raiding the dormitories of kids and their parents to confiscate and destroy letters from the children. This is in response to the ace reporting by @micarosenberg et al for ProPublica:

β€œI don’t want to be in this place I want to go to my school.”

- 7 year old imprisoned by ICE for 70 days in a concentration camp in Texas.

Today, after @propublica.org published this story, the camp was raided to confiscate letters from the children.

www.propublica.org/article/ice-...

17.02.2026 19:31 πŸ‘ 12165 πŸ” 6996 πŸ’¬ 324 πŸ“Œ 831

Excited to launch Principia, a nonprofit research organisation at the intersection of deep learning theory and AI safety.

Our goal is to develop theory for modern machine learning systems that can help us understand complex network behaviors, including those critical for AI safety and alignment.

1

16.02.2026 09:27 πŸ‘ 91 πŸ” 26 πŸ’¬ 1 πŸ“Œ 1
"Moderna's CEO announced the company will no longer invest in new Phase 3 vaccine trials for infectious diseases: 'You cannot make a return on investment if you don't have access to the U.S. market. Vaccines for Epstein-Barr virus, herpes, and shingles have been shelved.”
9:12 AM
Feb 12, 2026
604.8K Views

"Moderna's CEO announced the company will no longer invest in new Phase 3 vaccine trials for infectious diseases: 'You cannot make a return on investment if you don't have access to the U.S. market. Vaccines for Epstein-Barr virus, herpes, and shingles have been shelved.” 9:12 AM Feb 12, 2026 604.8K Views

In terms of what cures are being lost:

- Epstein-Barr virus is perhaps the major trigger for multiple sclerosis
- herpes simplex virus causes cold sores, genital herpes, infections in babies, deadly meningitis
- shingles virus causes an intensely painful disease

13.02.2026 05:44 πŸ‘ 12539 πŸ” 6207 πŸ’¬ 443 πŸ“Œ 783
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Astrocytes enable amygdala neural representations supporting memory - Nature Astrocytes in the basolateral amygdala dynamically track fear state and support fear memory retrieval and extinction.

Really nice work from the Holmes lab looking at amygdala astrocytes in fear memory and extinction!

www.nature.com/articles/s41...

11.02.2026 22:18 πŸ‘ 35 πŸ” 14 πŸ’¬ 0 πŸ“Œ 2
Comments contextualizing the Goodwin Procter report – MIT Media Lab I am writing this statement to clarify my interactions with Jeffrey Epstein as noted in the Goodwin Procter report, with the hope of providing additional conte…

To be fair, Ed Boyden wrote this in 2020: www.media.mit.edu/posts/commen...

Still curious what he discussed with zuck, elon etc at this meeting: www.justice.gov/epstein/file...

07.02.2026 22:06 πŸ‘ 1 πŸ” 1 πŸ’¬ 1 πŸ“Œ 0
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Gladys Mae West obituary: mathematician who pioneered GPS technology She made key contributions to US cold-war science despite facing huge barriers as a Black woman.

No joke: I got angry hate mail today for writing an obituary of a Black woman scientistβ€”because the person felt she did didn’t deserve the recognition.

Which just makes me want to share it again: www.nature.com/articles/d41...

06.02.2026 09:09 πŸ‘ 47157 πŸ” 19330 πŸ’¬ 1352 πŸ“Œ 795

β€œThe human body is an obstacle to efficiency β€” the limited head, the distracted heart, the tired limbs. Taking things inside saps energy and time, retaining them takes up space; and all for occasional use, if at all.”

06.02.2026 08:36 πŸ‘ 1 πŸ” 0 πŸ’¬ 0 πŸ“Œ 0

The only surprise is they admit it

04.02.2026 08:01 πŸ‘ 197 πŸ” 71 πŸ’¬ 11 πŸ“Œ 3
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hahahaha what

31.01.2026 16:42 πŸ‘ 8 πŸ” 5 πŸ’¬ 0 πŸ“Œ 1
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Save the date for the annual "Neural Circuits and Behaviour" satellite conference at the Canadian Association for Neuroscience annual meeting, cohosted by @franklandlab.bsky.social and myself on May 18, 2026. We have a great speaker lineup and will be selecting 4 trainees talks from our registrants!

26.01.2026 18:15 πŸ‘ 29 πŸ” 14 πŸ’¬ 2 πŸ“Œ 1

Fair enough. So we teleost people get beatings from up and down the evolutionary tree.

12.01.2026 21:08 πŸ‘ 3 πŸ” 0 πŸ’¬ 0 πŸ“Œ 1

HD system is in the zebrafish DTN & IPN, habenula gives visual input

12.01.2026 19:40 πŸ‘ 1 πŸ” 0 πŸ’¬ 1 πŸ“Œ 0
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Defending PhD student, looking over their thesis: β€œIf I knew then what I know now, I could’ve done all of this in like 9 months.”

A thread about my favorite pioneering cave explorers and why I don’t think AI will ever β€œsolve” biology.

11.01.2026 21:27 πŸ‘ 89 πŸ” 31 πŸ’¬ 3 πŸ“Œ 9
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How does the brain control locomotion? In our new preprint, we uncover a brain circuit in Drosophila that controls forward walking independently of turning. This dedicated locomotor circuit enables flexible motor control and might reflect a shared principle across species. doi.org/10.64898/202...

05.01.2026 16:24 πŸ‘ 78 πŸ” 26 πŸ’¬ 3 πŸ“Œ 3
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What in the Gestapo is going on in Grand Rapids?

Watch this activist get arrested *mid-interview* for speaking out against U.S. action in Venezuela.

05.01.2026 16:12 πŸ‘ 28538 πŸ” 14042 πŸ’¬ 1512 πŸ“Œ 1947
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Re-exposure to reward re-evaluates related memories To adapt behavior in changing environments, animals must continuously re-evaluate previously learned associations. This flexibility of memory systems …

Carolin Warnecke together with Hanna, Dennis, Bene & Kerstin from my lab show that re-exposure to reward diminishes multiple associated olfactory memories.

We’re hiring 2 postdocsβ€”DM/email me for details. #Postdoc #Hiring

www.sciencedirect.com/science/arti...

20.12.2025 18:49 πŸ‘ 21 πŸ” 9 πŸ’¬ 0 πŸ“Œ 1
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πŸ“’ Please help spread the word: We’re hiring a Head of Student & Postdoc Affairs to coordinate our international PhD program, provide guidance & career counseling, lead training programs, collaborate on EDI initiatives, and manage alumni relations. Apply at www.fmi.ch/education-ca...

04.12.2025 07:23 πŸ‘ 9 πŸ” 13 πŸ’¬ 0 πŸ“Œ 2
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1/n: A new collaborative preprint from the lab to start the year: "A multi-ring shifter network computes head direction in zebrafish" together with Siyuan Mei, Martin Stemmler and Andreas Herz from the LMU, Munich.

02.01.2026 17:52 πŸ‘ 58 πŸ” 26 πŸ’¬ 1 πŸ“Œ 3

That’s quite the pivot from LeCun who disagreed vigorously (let us say) with @garymarcus.bsky.social on this issue for quite some time…

02.01.2026 13:36 πŸ‘ 24 πŸ” 3 πŸ’¬ 0 πŸ“Œ 1
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40 percent of MRI signals misinterpreted Interpretation of numerous MRI data may be incorrect: blood flow is not a reliable indicator of brain activity.

"40 percent of MRI signals do not correspond to actual brain activity"; "Since tens of thousands of fMRI studies worldwide are based on this assumption, our results could lead to opposite interpretations in many of them.”
www.tum.de/en/news-and-...

28.12.2025 08:40 πŸ‘ 170 πŸ” 67 πŸ’¬ 5 πŸ“Œ 28

If the Romans had simply deported woke baby Jesus to South Sudan, a lot of trouble could have been avoided

24.12.2025 20:45 πŸ‘ 774 πŸ” 112 πŸ’¬ 13 πŸ“Œ 3

This is exactly why people claiming "it came up with a new set of experiments/ideas/concepts" are carrying water for the weasels trying to put genAI on everything. This is how we get science defunded. This is how your colleagues lose their jobs πŸ§ͺ

23.12.2025 14:55 πŸ‘ 31 πŸ” 10 πŸ’¬ 0 πŸ“Œ 0

I wouldn't describe Jay as "man in the middle" unless I were making sort of human centipede analogy.

23.12.2025 05:44 πŸ‘ 433 πŸ” 60 πŸ’¬ 17 πŸ“Œ 6
Landing and takeoff sensorimotor pathways illustrated alongside fly drawings showing behavioral responses.

Landing and takeoff sensorimotor pathways illustrated alongside fly drawings showing behavioral responses.

How do animals channel sensory information into motor pathways to generate flexible behavioral output? Excited to share a new preprint addressing this question by leveraging the new #maleCNS connectome, behavioral experiments, and in-vivo recordings: doi.org/10.64898/202.... A long🧡...

19.12.2025 07:02 πŸ‘ 70 πŸ” 29 πŸ’¬ 3 πŸ“Œ 1